Hui Li

Central South University, Ch’ang-sha-shih, Hunan, China

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Publications (287)865.18 Total impact

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    ABSTRACT: Reduced gray matter volume in left superior temporal gyrus (STG) is considered to be associated with auditory P300 amplitude in schizophrenia. Little is known about possible pathological circuits regarding sub-regions of STG that contribute to auditory P300 abnormality in schizophrenia. The current study investigated gray matter volume in STG and functional connectivity of Heschl's gyrus in first-episode schizophrenia (FESZ), as well as their correlations with P300 amplitude.
    Schizophrenia Research 10/2014; · 4.59 Impact Factor
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    ABSTRACT: In this paper, we develop a simple vesicle-assisted chemical reduction approach for synthesizing hollow Ni-Co-B nanospheres. With various characterizations, the resulting Ni-Co-B nanospheres are identified to be amorphous alloys with a hollow chamber. Coexistence of NiII and CoII species play a significant role in fabricating hollow nanospheric structures, because only solid nanoparticles can be obtained in the presence of mono-metallic precursor. During liquid-phase hydrogenation of 2-ethyl-2-hexenaldehyde, hollow Ni-Co-B catalyst displays significant bi-site catalysis from bimetals and delivers much greater activity as well as better selectivity than those associated with the dense Ni-Co-B catalyst. Additionally, this catalyst is also easily handled in liquid phase reaction due to its lower density and magnetic property. The material design concept present in this work opens a new avenue for the development of hollow non-noble metallic nanospheres and will draw more attention in the foreseeable future.
    J. Mater. Chem. A. 09/2014;
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    ABSTRACT: Panic disorder (PD) is a common type of anxiety disorder, characterized by unexpected and repeated panic attacks or fear of future panic attacks, or both. Individuals with PD are often resistant to pharmacological or psychological treatments and this can lead to the disorder becoming a chronic and disabling illness. Repetitive transcranial magnetic stimulation (rTMS) can deliver sustained and spatially selective current to suppress or induce cortical excitability, and its therapeutic effect on pathological neuronal activity in people with PD has already been examined in case studies and clinical trials. However, a systematic review is necessary to assess the efficacy and safety of rTMS for PD.
    Cochrane database of systematic reviews (Online) 09/2014; 9:CD009083. · 5.70 Impact Factor
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    ABSTRACT: 1. Pathogens can affect their hosts and change community composition and structure. Pathogens may be key determinants of biological invasions. However, few empirical studies exist examining how non-native plants drive their invasions through indirect effects involved with pathogens. Here, indirect effects refer to how one species alters the effect that another species has on a third.2. Fusarium palustre was associated with the dieback of Spartina alterniflora in its native North American salt marshes. Native plant Phragmites australis was also found to die back in the Dongtan wetland of the Chinese Yangtze River estuary invaded by non-native Spartina alterniflora. This phenomenon suggests that Spartina might not escape from its pathogen when being introduced from its native North America, and has indirectly caused the dieback of Phragmites in China.3. To investigate the indirect effect of Spartina involving Fusarium, we sampled plants and soils in dieback patches to isolate the pathogen. Next, we used an artificial inoculation study to determine the virulence of Fusarium to both Phragmites and Spartina. Finally, the spatial distribution of Fusarium was studied through examining its incidence in salt marshes along the east coast of China.4. The endophytic fungus F. palustre was found to be closely associated with Phragmites dieback in the Dongtan wetland and it is likely that it was transported by non-native Spartina from their native North American salt marshes to the Chinese salt marshes. The spillover of F. palustre from non-native Spartina to native Phragmites might subsequently facilitate Spartina invasion.5. Synthesis. Invasive plants do not only directly compete with native plants, but also indirectly cause pathogen infection on the latter, by acting as vectors and reservoirs for pathogens shared with native plants. Our findings highlight the significance of indirect effects involving pathogens in biological invasions. It is necessary to consider these pathogen-mediated indirect effects of non-native plant species in multi-host-pathogen systems for management and restoration purposes.This article is protected by copyright. All rights reserved.
    Journal of Ecology 06/2014; · 5.43 Impact Factor
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    ABSTRACT: Neuronal oscillations reflect the activity of neuronal ensembles engaged in integrative cognition, and may serve as a functional measure for the cognitive impairment in schizophrenia. This study aims to reveal the abnormal amplitude dynamics of electroencephalogram (EEG) oscillations in schizophrenia patients on multiple time scales. EEGs were recorded from schizophrenia patients ( n = 19) and healthy controls ( n = 16) while they were at resting state with eyes closed, at resting state with eyes open, and at watching video. Detrended fluctuation analysis and measures of life-time and waiting-time were used to characterize the abnormal dynamics of EEG oscillations on both long (1-20 s) and short (≤1 s) time scales. Abnormal dynamics of EEG oscillations in alpha and beta bands were observed. In particular, compared with healthy controls, schizophrenia patients have smaller DFA exponent (implying weaker long-range temporal correlation) in the left fronto-temporal area and smaller DFA exponent, smaller life-time (indicating shorter oscillation burst), and smaller waiting-time in the occipital area in beta band at resting state with eyes open. In addition, schizophrenia patients have larger DFA exponent, larger life-time, and larger waiting-time at some clustered channels in the temporo-parietal area in alpha band at watching video. The present results provide new insights for cognitive deficits and the underlying neuronal dysfunction in schizophrenia.
    IEEE transactions on bio-medical engineering 06/2014; 61(6):1756-64. · 2.15 Impact Factor
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    ABSTRACT: A new type of magnetic halloysite nanotubes molecularly imprinted polymer (MHNTs@MIP) based on halloysite nanotubes (HNTs) with embedded magnetic nanoparticles was introduced in this study. MHNTs@MIP was prepared through surface imprinting technology, using 2,4-dichlorophenoxyacetic acid (2,4-D) as a template, 4-vinylpyridine as the monomer, divinylbenzene as cross-linking agents, and 2,2-azodiisobutyronitrile as initiator. MHNTs@MIP was characterized by Fourier Transform Infrared Spectrometer, transmission electron microscopy, X-ray diffraction, and vibrating sample magnetometer. MHNTs@MIP exhibited rapid and reliable analysis with supermagnetic properties, as well as repeated use and template-specific recognition. The adsorption capacity of magnetic halloysite nanotubes non-imprinted polymer (MHNTs@NIP) and MHNTs@MIP was 10.3mg/g and 35.2mg/g, respectively. In the detailed discussion on specific selectivity, MHNTs@MIP can be applied as an adsorbent for sample pretreatment extraction and obtain high recoveries of about 85-94%. After extraction, high-performance liquid chromatography was used to detect 2,4-D residue in water.
    Journal of hazardous materials. 05/2014; 276C:58-65.
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    ABSTRACT: A combined quantum mechanical/molecular mechanical/continuum (QM/MM/C) style second order Møller-Plesset perturbation theory (MP2) method that incorporates induced dipole polarizable force field and induced surface charge continuum solvation model is established. The Z-vector method is modified to include induced dipoles and induced surface charges to determine the MP2 response density matrix, which can be used to evaluate MP2 properties. In particular, analytic nuclear gradient is derived and implemented for this method. Using the Assisted Model Building with Energy Refinement induced dipole polarizable protein force field, the QM/MM/C style MP2 method is used to study the hydrogen bonding distances and strengths of the photoactive yellow protein chromopore in the wild type and the Glu46Gln mutant.
    The Journal of Chemical Physics 05/2014; 140(17):174115. · 3.12 Impact Factor
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    ABSTRACT: This paper presents the influence of graphene on the vulcanization kinetics of styrene butadiene rubber (SBR) with dicumyl peroxide. A curemeter and a differential scanning calorimeter were used to investigate the cure kinetics, from which the kinetic parameters and apparent activation energy were obtained. It turns out that with increasing graphene loading, the induction period of the vulcanization process of SBR is remarkably reduced at low graphene loading and then levels off; on the other hand, the optimum cure time shows a monotonous decrease. As a result, the vulcanization rate is suppressed at first and then accelerated, and the corresponding activation energy increases slightly at first and then decreases. Upon adding graphene, the crosslinking density of the nanocomposites increases, because graphene takes part in the vulcanization process.
    Chinese Journal of Polymer Science 05/2014; 32(5). · 1.27 Impact Factor
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    ABSTRACT: Ensuring high quality of service (QoS) of multicast video stream over next generation network is a challenging issue, and how to implement the wire-speed multicast with hardware logical support in the network nodes of every hierarchy is a key solution to achieve high QoS multicast. Currently, the multicast packets are processed in this way, in which they are copied and then scheduled by ports, lastly, sent respectively. But this approach cannot ensure high QoS in real-time applications. Moreover, the traditional hardware solutions do not possess excellent large-scale scalability owning to their own bottlenecks. In this project, we have constructed a wire-speed multicast switching structure based on Multipath Self-routing Switching Structure, and implemented it on a Stratix IV FPGA chip. Additionally, we have designed the signaling system and control mechanism to support the process of self-routing and wire-speed fan-out copy of multicast packets.
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    ABSTRACT: In this work, we reported a scanometric assay system based on the aptamer-functionalized silver nanoparticles (apt-AgNPs) for detection of platelet-derived growth factor-BB (PDGF-BB) protein. The aptamer and ssDNA were bound with silver nanoparticles by self-assembly of sulfhydryl group at 5' end to form the apt-AgNPs probe. The apt-AgNPs probe can catalyze the reduction of metallic ions in color agent to generate metal deposition that can be captured both by human eyes and a flatbed scanner. Two different color agents, silver enhancer solution and color agent 1 (10mM HAuCl4+2mM hydroquinone) were used to develop silver and gold shell on the surface of AgNPs separately. The results demonstrated that the formation of Ag core-Au shell structure had some advantages especially in the low concentrations. The apt-AgNPs probe coupled with color agent 1 showed remarkable superiority in both sensitivity and detection limit compared to the apt-AuNPs system. The apt-AgNPs system also produced a wider linear range from 1.56ngmL(-1) to 100ngmL(-1) for PDGF-BB with the detection limit lower than 1.56ngmL(-1). The present strategy was applied to the determination of PDGF-BB in 10% serum, and the results showed that it had good specificity in complex biological media.
    Analytica chimica acta 02/2014; 812:152-60. · 4.31 Impact Factor
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    ABSTRACT: Electroconvulsive therapy (ECT) is the most effective treatment of depression. During the last decades Repetitive Transcranial magnetic stimulation (rTMS), an alternative method using electric stimulation of the brain, has revealed possible alternative to ECT in the treatment of depression. There are some clinical trials comparing their efficacies and safeties but without clear conclusions, mainly due to their small sample sizes. In the present study, a meta-analysis had been carried out to gain statistical power. Outcomes were response, remission, acceptability and cognitive effects in depression. Following a comprehensive literature search that included both English and Chinese language databases, we identified all randomized controlled trials that directly compared rTMS and ECT for major depression. 10 articles (9 trials) with a total of 425 patients were identified. Methodological quality, heterogeneity, sensitivity and publication bias were systematically evaluated. ECT was superior to high frequency rTMS in terms of response (64.4% vs. 48.7%, RR=1.41, p=0.03), remission (52.9% vs. 33.6%, RR=1.38, p=0.006) while discontinuation was not significantly different between the two treatments (8.3% vs. 9.4%, RR=1.11, p=0.80). According to the subgroup analysis, the superiority of ECT was more apparent in those with psychotic depression, whilst high frequency rTMS was as effective as ECT in those with non-psychotic depression. The same results were gained in the comparison of ECT with low frequency rTMS. ECT had a non-significant advantage over high frequency rTMS on the overall improvement in HAMD scores (p=0.11). There was insufficient data on medium or long term efficacy. Both rTMS and ECT were well tolerated with only minor side effects reported. Results based on 3 studies suggested that specific cognitive domains such as visual memory and verbal fluency were more impaired in patients receiving ECT. In conclusion, ECT seemed more effective than and at least as acceptable as rTMS in the short term, especially in the presence of psychotic depression. This review identified the lack of good quality trials comparing the long-term outcome and cognitive effects of rTMS and ECT, especially using approaches to optimize stimulus delivery and reduce clinical heterogeneity.
    Progress in Neuro-Psychopharmacology and Biological Psychiatry 02/2014; · 3.55 Impact Factor
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    ABSTRACT: This paper presents an ultrasensitive fluorescent detection method through fabricating a silver microarray substrate. Silver nanoparticles (AgNPs) and Ag@Au core-shell nanoparticles with different sizes were first synthesized by a seed-mediated growth method and the metal-enhanced fluorescence of these nanoparticles on different fluorescent dyes was investigated. The results indicated that AgNPs could act as a versatile and effective metal-enhanced fluorescence material for various fluorophores, whereas the enhanced fluorescence from Ag@Au was limited only to certain fluorophores. When the AgNPs were functionalized with aptamers and fluorescent dyes, a good analytical performance for simultaneous detection of human IgE and platelet-derived growth factor-BB (PDGF-BB) could be obtained. AgNPs were not only used as detection tags but also used to fabricate the plasmonic microarray substrate to further enhance the sensitivity of fluorescent detection. As a result, a linear response to PDGF-BB concentration was obtained in the concentration range of 16 pg mL(-1) to 50 ng mL(-1), and the detection limit was 3.2 pg mL(-1). In addition, the AgNP modified plasmonic microarrays showed remarkable recovery and no significant interference from human serum when applied to 2 ng mL(-1) PDGF-BB concentration. The plasmonic microarray substrate demonstrated both high specificity and sensitivity for protein microarray detection and this novel approach has great potential for ultrasensitive detection of protein biomarkers in the bio-medical field.
    The Analyst 02/2014; · 4.23 Impact Factor
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    ABSTRACT: Nanomaterials as tracing tags have been widely used in biosensors with high sensitivity and selectivity. In this work, a signal amplification electrochemical aptamer sensing strategy for the detection of protein was designed by combining the hybridization inducing aggregate of DNA functionalized silver nanoparticles (AgNPs) and differential pulse stripping voltammetry (DPSV) detection. The multi-probes containing hybridization DNA and the aptamer were anchored onto the silver nanoparticles. The protein assay was prepared through the immobilization of capture aptamer that specifically recognizes platelet-derived growth factor (PDGF-BB) on gold nanoparticles modified screen printed electrode (SPE) array. After a sandwich type reaction, two kinds of DNA-modified AgNPs were simultaneously added on the electrode surface for specifically recognizing PDGF-BB and forming the AgNPs aggregate caused by in-situ hybridization of DNA. Compared to the signal labeled tag, the tracing aggregate tags showed a strong electro-activity for signal amplification through stripping detection of silver after pre-oxidization. By using the hybridization inducing aggregate as electrochemical readouts, the sensor showed wide linear range and low detection limit. The hybridization inducing AgNPs aggregate were further used as tracing tags in multiplied proteins assays for PDGF-BB and Thrombin by using the SPE array chip as sensing platform. The cross-talk between different aptamer modified electrodes on the same array was avoided because of the advantage of labeled AgNPs. The array detection was also applied in the logic gate operation. The proposed method described here is ideal for multi-analytes determination in clinical diagnostics with good analytical performance.
    Analytical Chemistry 02/2014; · 5.70 Impact Factor
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    ABSTRACT: Oleic acid modified iron oxide nanoparticles (IONs) with different sizes were synthesized and mixed with styrene-butadiene-styrene block copolymer (SBS) with a lamellar structure. The octadecene segments on the oleic acid molecules have chemical affinity with the polybutadiene (PB) blocks, which makes IONs tend to be selectively confined the microphase-separated PB domains. However, the dispersion state strongly depends on the ratio of the particle diameter (d) to the lamellar thickness (l) of the PB domains, which further changes the phase separation of SBS. When d/l~0.5, IONs are concentrated in the middle of the PB layers at low particle loading. Upon increasing the particle loading, part of IONs contact with each other to form long strings due to their strong magnetic interactions. Away from the strings, IONs are either selectively dispersed in the middle and at the interfaces of the PB domains, or randomly distributed at some regions in which the phase separation of SBS is suppressed. The phase separation of SBS transforms from the lamellar structure to a cylinder structure when the IONs loading is higher than 16.7 wt%. As d is comparable to l, IONs aggregate to form clusters of 100 to 300 nm in size, but within the clusters IONs are still selectively dispersed in the PB domains instead of forming macroscopic phase separation. It is interpreted in terms of the relatively small conformational entropy of the middle blocks of SBS, thus incorporation of nanoparticles does not lead to a much loss of the conformational entropy. Although incorporation of IONs with d/l~1 significantly increases the interfacial curvature and roughness, it has less influence on the phase separation structure of SBS due to the inhomogeneous dispersion. When d is larger than l, IONs are macroscopically separated from the SBS matrix to form clusters of hundreds of nanometers to several micrometers. More interestingly, the phase separation of SBS transforms from the lamellar structure to a two-phase co-continuous structure, probably due to the rearrangement of SBS molecules to cover the clusters with PB segments and the strong magnetic interaction exerting additional force on the SBS matrix during the evaporation of the solvent and the subsequent thermal annealing process.
    The Journal of Physical Chemistry B 01/2014; · 3.61 Impact Factor
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    ABSTRACT: In this paper, we developed a simple and rapid colorimetric assay for protein detection based on the reduction of dye molecules catalyzed by silver nanoparticles (AgNPs). Aptamer-modified magnetic particles and aptamer-functionalized AgNPs were employed as capture and detection probes, respectively. Introduction of thrombin as target protein could form a sandwich-type complex involving catalytically active AgNPs, whose catalytic activity was monitored on the catalytic reduction of rhodamine B (RhB) by sodium borohydride (NaBH4). The amount of immobilized AgNPs on the complex increased along with the increase of the thrombin concentration, thus the detection of thrombin was achieved via recording the decrease in absorbance corresponding to RhB. This method has adopted several advantages from the key factors involved, i.e., the sandwich binding of affinity aptamers contributed to the increased specificity; magnetic particles could result in rapid capture and separation processes; the conjugation of AgNPs would lead to a clear visual detection. It allows for the detection limit of thrombin down to picomolar level by the naked eye, with remarkable selectivity over other proteins. Moreover, it is possible to apply this method to the other targets with two binding sites as well.
    Analytica chimica acta 01/2014; 807:120-5. · 4.31 Impact Factor
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    ABSTRACT: In order to provide fault-tolerance and guarantee reliability, data redundancy should be introduced in distributed storage systems. The emerging coding techniques for storage such as fractional repetition codes, provide the required redundancy more efficiently than the conventional replication scheme. In this letter, we extend the construction of fractional repetition codes and present a new coding scheme, termed general fractional repetition codes. The proposed codes can be applied to storage systems in which the storage capacities of nodes may be different. Based on a combinatorial structure known as group divisible design, the new code construction is available for a large set of parameters. The performance of the proposed codes is evaluated by a metric called node repair alternativity, which measures the number of different subsets of nodes that enable the repair of a specific failed node.
    IEEE Communications Letters 01/2014; 18(4):660-663. · 1.16 Impact Factor
  • Hui Li, Danke Xu
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    ABSTRACT: Silver nanoparticles (AgNPs) have attracted increasing attention for applications in bioanalytical chemistry because of their unique optical, electrical, chemical and catalytic properties. The review describes the properties of AgNPs and covers recent developments in bioanalytical applications based on the electrochemical, optical and catalytic properties of AgNPs.
    TrAC Trends in Analytical Chemistry 01/2014; · 6.35 Impact Factor
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    ABSTRACT: With a significant advance in ciphertext searchability, public-key encryption with keyword search (PEKS) guarantees both security and convenience for outsourced keyword search over ciphertexts. In this paper, we establish static index (SI) and dynamic index (DI) for PEKS to make search efficient and secure in the state of the art. Suppose there are uu senders to generate nn searchable ciphertexts for ww keywords. The search complexity of PEKS always is O(n)O(n) for each query, even if the keyword has been searched for multiple times. It is obviously inefficient for massive searchable ciphertexts. Fortunately, SI and DI help PEKS lowering the burden respectively in two phases: if the queried keyword is the first time to be searched, apply SI to reduce the complexity from O(n)O(n) to O(u⋅w)O(u⋅w); otherwise, apply DI to reduce the complexity from O(n)O(n) to O(w)O(w). Because DI is invalid for the first time search on any keyword, SI and DI are simultaneously applied with PEKS to complete our work as the secure hybrid indexed search (SHIS) scheme. Since u≪w≪nu≪w≪n in practice, our SHIS scheme is significantly more efficient than PEKS as demonstrated by our analysis. In the end, we show the extension of SHIS to multi-receiver applications, which is absent for pure PEKS.
    Future Generation Computer Systems 01/2014; · 2.64 Impact Factor
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    ABSTRACT: We have performed a benchmark study of molecular O2 binding on Aun (n = 1–3) clusters using density-functional theory and high-level coupled-cluster calculations. Based on the computed structural and energetic properties of O2 binding on anionic, cationic, and neutral Aun (n = 1–3), we find that the hybrid functionals (HSE06, PBE0, and B3LYP) and the M06 functional with large basis sets give much more reasonable binding energy of O2 and O–O bond length compared to GGA functionals (PBE and TPSS). In particular, the HSE06 functional gives the best agreement with CCSD(T)//MP2 method in O2 binding energy on neutral Au3.
    Chemical Physics Letters 01/2014; 592:127–131. · 2.15 Impact Factor
  • Journal of Hazardous Materials. 01/2014; 276:58–65.

Publication Stats

2k Citations
865.18 Total Impact Points


  • 2014
    • Central South University
      • Department of Chemistry Engineering
      Ch’ang-sha-shih, Hunan, China
  • 2008–2014
    • University of Nebraska at Lincoln
      • Department of Chemistry
      Lincoln, Nebraska, United States
    • Nanjing University
      • Department of Chemical Engineering
      Nan-ching, Jiangsu Sheng, China
    • South China Normal University
      Shengcheng, Guangdong, China
  • 2007–2014
    • Peking University
      • Shenzhen Graduate School
      Peping, Beijing, China
    • University of Texas Southwestern Medical Center
      Dallas, Texas, United States
    • China University of Mining Technology
      Wu-hsien, Jiangsu Sheng, China
  • 2006–2014
    • Shanghai Jiao Tong University
      • School of Medicine
      Shanghai, Shanghai Shi, China
    • National Institute of Advanced Industrial Science and Technology
      • Computational Biology Research Center
      Tsukuba, Ibaraki, Japan
  • 1999–2014
    • Fudan University
      • • Institute of Biodiversity Science
      • • Department of Chemistry
      Shanghai, Shanghai Shi, China
  • 2013
    • Sichuan University of Science and Engineering
      Hua-yang, Sichuan, China
    • Beijing University of Technology
      Peping, Beijing, China
  • 2009–2013
    • Northeast Institute of Geography and Agroecology
      • Institute of Physics
      Beijing, Beijing Shi, China
    • Renji Hospital
      Shanghai, Shanghai Shi, China
    • Michigan State University
      East Lansing, Michigan, United States
    • Huazhong University of Science and Technology
      • Department of Electronics and Information Engineering
      Wu-han-shih, Hubei, China
    • China Agricultural University
      • College of Information and Electrical Engineering
      Peping, Beijing, China
  • 2001–2013
    • Chinese Academy of Sciences
      • • Institute of Physics
      • • Institute of Health Sciences
      • • Institute of High Energy Physics
      • • Condensed Matter Physics
      Peping, Beijing, China
  • 2012
    • Southwest Jiaotong University
      • School of Information Science and Technology
      Hua-yang, Sichuan, China
    • Shanxi Normal University
      Saratsi, Shanxi Sheng, China
  • 2006–2012
    • Tsinghua University
      • • Department of Industrial Engineering
      • • Department of Architecture
      Beijing, Beijing Shi, China
    • Shanghai Normal University
      Shanghai, Shanghai Shi, China
  • 2010–2011
    • China Pharmaceutical University
      • Division of Analytical Chemistry
      Nan-ching-hsü, Jiangxi Sheng, China
  • 2008–2009
    • National University of Singapore
      • • Department of Chemistry
      • • Department of Physics
      Singapore, Singapore
  • 2006–2007
    • Iowa State University
      • Department of Chemistry
      Ames, IA, United States
  • 2002–2006
    • University of Iowa
      • Department of Chemistry
      Iowa City, IA, United States
  • 2004–2005
    • Second Military Medical University, Shanghai
      Shanghai, Shanghai Shi, China
    • Shanghai Institutes for Biological Sciences
      Shanghai, Shanghai Shi, China
  • 1998–1999
    • Shanghai Institute of Health Sciences
      Shanghai, Shanghai Shi, China