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ABSTRACT: To assess the short-term efficacy of Semont maneuver for unilateral posterior semicircular canal benign paroxysmal positional vertigo (PC-BPPV).
The short-term efficacy of Semont maneuver was compared with a sham procedure in 128 patients with PC-BPPV by using a double-blinded prospective randomized controlled trial in the setting of a neurologic outpatient clinic in China. Analysis was based on the symptomatic status and the Dix-Hallpike maneuver on the fourth day. At this time, patients in both groups with a still positive Dix-Hallpike test were treated with Semont maneuver, and outcome was again assessed on the seventh day.
On the fourth day, 55 (84.62%) of 65 patients in the treatment group showed complete resolution of symptoms compared with 9 (14.29%) of 63 patients in the control group. (p < 0.001) 59 (90.77%) of 65 and 52 (82.54%) of 63 patients reported resolution of symptoms in the treatment and original sham group, respectively (p = 0.17).
Semont maneuver is shown to resolve PC-BPPV effectively, and patients should receive Semont maneuver once the PC-BPPV diagnosis was confirmed.
Otology & neurotology: official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 09/2012; 33(7):1127-30. · 1.44 Impact Factor
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ABSTRACT: The aim of this study was to investigate the expression profiles of microRNAs (miRNAs) in pediatric asthma and to determine candidate miRNAs responsible for the pathogenesis of this disease. Microarrays were used to detect the differences in the miRNA expression levels between asthmatic children and controls. Airway inflammation was evaluated by cell counting and tissue biopsy in an ovalbumin (OVA)-induced murine asthma model. Real-time polymerase chain reaction (PCR) was used to verify the differentially expressed miRNAs. The targets of the identified miRNAs were analyzed by bioinformatic analysis. The sprouty-related protein with an EVH1 domain-2 (Spred-2) protein content was assessed by western blotting. Differences were observed in the expression of miRNAs between the asthmatic children and controls. Upregulation of miRNA-221 and miRNA-485-3p in pediatric asthmatics and murine asthma models were verified by real-time PCR. Spred-2, a predicted target of miRNA-221 and miRNA-485-3p, was downregulated in murine asthma models. Upregulation of miRNA-221 and miRNA-485-3p may regulate the pathogenesis of asthma.
Molecular Medicine Reports 08/2012; 6(5):1178-82. · 0.42 Impact Factor
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ABSTRACT: A new type of defect-less, layered organo-titanosilicate is synthesized using a simple, template-free, evaporation-induced self-assembly process. The obtained layered material has superhydrophobicity and exhibits promising catalytic activity in the epoxidation of olefins using 30% H(2)O(2) aqueous solution as oxidant at room temperature.
Chemical Communications 06/2012; 48(55):6954-6. · 6.17 Impact Factor
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ABSTRACT: We report on a simple scheme to precisely control carrier-envelope phase of a nonlinear-polarization-rotation mode-locked self-started Yb-fiber laser system with an average output power of ∼7 W and a pulse width of 130 fs. The offset frequency was locked to the repetition rate of ∼64.5 MHz with a relative linewidth of ∼1.4 MHz by using a self-referenced feed-forward scheme based on an acousto-optic frequency shifter. The phase noise and timing jitter were calculated to be 370 mrad and 120 as, respectively.
Optics Letters 05/2012; 37(9):1511-3. · 3.40 Impact Factor
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Qiming Liu,
Xuan He,
Xiujian Zhao,
Feng Ren,
Xiangheng Xiao,
Changzhong Jiang,
Xiong Zhou,
Liping Lu, Hui Zhou,
Shixiong Qian,
B. Poumellec,
M. Lancry
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ABSTRACT: Ag-nanoparticles were embedded in 56GeS2–24Ga2S3–20KBr chalcohalide glass with average size varying from 100 to 300nm. A large femtosecond optical Kerr effect indicated
an enhancement of third-order optical nonlinearity due to Ag-nanoparticles observed by AFM images. Among these Ag-nanoparticles-embedded
chalcohalide glass samples, the sample (c) with the second largest implanting dose 1×1017ions/cm2 showed the largest value of χ(3) 5.34×10−13esu, which was ten times larger than that of the substrate. The nonlinear relation between the implanted dose and third-order
optical nonlinearity is strongly related to the intrinsic local field and Ag-nanoparticles interaction in the glasses.
KeywordsChalocohalide glass–Ag-nanoparticle–Optical Kerr effect–Third-order optical nonlinearity
Journal of Nanoparticle Research 04/2012; 13(9):3693-3697. · 3.29 Impact Factor
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ABSTRACT: This paper aims at a numerical study of coupled thermal, hydrological and mechanical processes in the excavation disturbed
zones (EDZ) around nuclear waste emplacement drifts in fractured crystalline rocks. The study was conducted for two model
domains close to an emplacement tunnel; (1) a near-field domain and (2) a smaller wall-block domain. Goodman element and weak
element were used to represent the fractures in the rock mass and the rock matrix was represented as elasto-visco-plastic
material. Mohr–Coulomb criterion and a non-associated plastic flow rule were adopted to consider the viscoplastic deformation
in the EDZ. A relation between volumetric strain and permeability was established. Using a self-developed EPCA2D code, the elastic, elasto-plastic and creep analyses to study the evolution of stress and deformations, as well as failure
and permeability evolution in the EDZ were conducted. Results indicate a strong impact of fractures, plastic deformation and
time effects on the behavior of EDZ especially the evolution of permeability around the drift.
Environmental Geology 04/2012; 57(6):1299-1311. · 1.13 Impact Factor
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ABSTRACT: To analyze the stroma changes of benign and malignant human prostate tissues.
For the identification of stroma cells phenotype in human prostate cancer and benign prostate hyperplasia tissues, Masson method and immunohistochemical analysis of α-smooth muscle actin (α-SMA), desmin, and vimentin were performed. The relative volume of intratumor stroma (0%, Grade 0; 1% - 33%, Grade 1; 34% - 66%, Grade 2; 67% - 100%, Grade 3) were quantified and analyzed in local and advanced prostate cancer tissues.
Stroma myofibroblasts in prostate cancer were stained green by Masson staining and showed a co-expression of α-SMA and vimentin without an expression of desmin. It was significantly different from smooth muscle cells in benign prostate hyperplasia stained red and co-expressing a-SMA and desmin. Statistical analysis showed that high stroma volume (Grade 2/3) in advanced prostate cancer were significantly higher than that in an early stage of prostate cancer (83% vs 55%, P < 0.05).
Significant phenotypic differences of stroma cells existed in benign and malignant human prostate tissues. A high expression of myofibroblasts in advanced prostate cancer may play an important role in cancer progression. And its clinical significance should raise a high alert.
Zhonghua yi xue za zhi 02/2012; 92(8):516-9.
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M Tony Hollingsworth,
Gerald W Hart,
James C Paulson,
Elizabeth Stansell,
Kevin Canis,
I-Cheuh Huang,
Maria Panico,
Howard Morris,
Stuart Haslam,
Michael Farzan, [......],
Kazunori Hamamura,
Takenosuke Yoshida,
Kaoru Akita,
Tetsuya Okajima,
Keiko Furukawa,
Takeshi Urano,
Koichi Furukawa,
L Renee Ruhaak,
Suzanne Miyamoto,
Carlito B Lebrilla
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ABSTRACT: Cell surface mucins configure the cell surface by presenting extended protein backbones that are heavily O-glycosylated. The glycopeptide structures establish physicochemical properties at the cell surface that enable and block the formation of biologically important molecular complexes. Some mucins, such as MUC1, associate with receptor tyrosine kinases and other cell surface receptors, and engage in signal transduction in order to communicate information regarding conditions at the cell surface to the nucleus. In that context, the MUC1 cytoplasmic tail (MUC1CT) receives phosphorylation signals from receptor tyrosine kinases and serine/threonine kinases, which enables its association with different signaling complexes that conduct these signals to the nucleus and perhaps other subcellular organelles. We have detected the MUC1CT at promoters of over 500 genes, in association with several different transcription factors, and have shown that promoter occupancy can vary under different growth factor conditions. However, the full biochemical nature of the nuclear forms of MUC1 and its function at these promoter regions remain undefined. I will present evidence that nuclear forms of the MUC1CT include extracellular and cytoplasmic tail domains. In addition, I will discuss evidence for a hypothesis that the MUC1CT possesses a novel catalytic function that enables remodeling of the transcription factor occupancy of promoters, and thereby engages in regulation of gene expression.
Glycobiology 11/2011; 21(11):1454-531. · 3.58 Impact Factor
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ABSTRACT: Ag-nanoparticles were embedded in the 56GeS2–24Ga2S3–20KBr chalcohalide glasses with varied doses by ion implantation. Ag-nanoparticles were observed in the AFM images of all implanted samples. The thirdorder optical nonlinearity of Ag-implanted chalcohalide glasses was investigated by the femtosecond Z-scan measurements. The results indicated an enhancement of third-order optical nonlinearity due to the formation of Ag-nanoparticles in glasses. The relation between implanting dose and third-order optical nonlinearity was strongly related to the intrinsic local field and interaction of Ag-nanoparticles.
Journal of Non-Crystalline Solids 01/2011; 357(11-13):2320-2323. · 1.54 Impact Factor
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ABSTRACT: Thirteen triterpenoids, including three new ones, miyoshianols A (1), B (2) and C (3), were isolated from Huperzia miyoshiana. The structures of these new compounds were established as 3-O-dihydroferuloyltohogenol (1), 16-oxo-3β, 21β-dihydroxy-serrat-14-en-24-ferulate (2) and 16-oxo-3, 21β-dihydroxyserrat-14-en-24-ferulate (3), respectively, on the basis of their spectroscopic analysis.
Chinese Journal of Chemistry 08/2010; 21(10):1364 - 1368. · 0.75 Impact Factor
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ABSTRACT: The interaction of fluorocarbon containing hydrophobically modified polyelectrolyte (FMPAANa) with two kinds of non-ionic surfactants (hydrogenated and fluorinated) in a semidilute (0.5 wt%) aqueous solution had been studied by rheological measurements. Association behavior was found in both systems. The hydrophobic interaction of FMPAANa with fluorinated surfactant (FC171) is much stronger than that with hydrogenated surfactant (NP7.5) at low surfactant concentrations. The interaction is strengthened by surfactants being added for the density of active junctions increased. Whereas distinct phenomena for FC171 and NP7.5 start to be found as the surfactants added over their respective certain concentration. The interaction of polyelectrolyte with fluorinated surfactant increases dramatically while that with hydrogenated surfactant decreases.
Chinese Journal of Chemistry 08/2010; 20(5):509 - 513. · 0.75 Impact Factor
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ABSTRACT: The interactions between fluorocarbon-modified poly (sodium acrylate) and various kinds of added surfactants have been studied by means of viscometric measurement. Association behavior was found in both hydrogenated and fluorinated anionic, nonionic and cationic surfactants. Among them, the interactions between fluorocarbon-modified poly (sodium acrylate) and cationic surfactants are the strongest, owing to the cooperation of both electrostatic attractions and hydrophobic associations. The anionic surfactants have the weakest effects on the solution properties because of the existence of unfavorable electrostatic repulsion. The hydrophobic interactions between copolymers and fluorinated surfactants are much stronger than those between copolymers and hydrogenated surfactants.
Chinese Journal of Chemistry 08/2010; 19(8):745 - 750. · 0.75 Impact Factor
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ABSTRACT: The interaction of fluorocarbon- containing hydrophobically modified sodium polyacrylic acid (FMPAANa) (0.5 wt%) with various surfactants (anionic, nonionic and cationic) has been investigated by rheological measurements. Different rheological behaviors are displayed for ionic surfactants and nonionic surfactants. Fluorinated surfactants have stronger affinity with polyelectrolyte hydrophobes comparing with hydrogenated surfactants. The hydrophobic association of FMPAANa with a cationic surfactant (CTAB) and a fluorinated nonionic surfactant (FC171) is much stronger than with a nonionic surfactant (NP7. 5) and an anionic surfactant (FC143). Further investigation of the effects of temperature on solution properties shows that the dissociation energy Em is correlated to the strength of the aggregated junctions.
Chinese Journal of Chemistry 08/2010; 19(12):1198 - 1204. · 0.75 Impact Factor
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ABSTRACT: This paper describes a novel hierarchical framework for automatic identification of plankton images, which is motivated by the semantics description of planktons used in the biology textbooks. The framework discretizes the identification of plankton into the recognition of various high-level shape semantics features. The semantics features are modeled with some manual instructions. Distinct from the previous approaches, such as "PCA+SVM" and "classifier stacking", our algorithm is more similar to the recognition procedure used by the biology experts, and the extracted features are more efficient for identification. The approach is tested on a collection of more than 2000 plankton images. Results demonstrate that the proposed approach has a satisfying classification accuracy and robustness to different number of training samples.
Bioinformatics and Biomedical Engineering, 2008. ICBBE 2008. The 2nd International Conference on; 06/2008
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Annalen der Chemie und Pharmacie 11/2006; 2007(4):639 - 644. · 3.10 Impact Factor
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ABSTRACT: Films of a series of polymers with variable CF2 segments were studied by angle-dependent X-ray photoelectron spectroscopy (ADXPS) and time-of-flight secondary ion mass spectroscopy (ToF-SIMS). The effects of the length of the CF2 segment on the surface composition of the polymers were investigated. ADXPS results indicated that the CF2 segment segregated on the surface of the polymers after thermal annealing at temperatures above their bulk glass transition temperatures when the number of CF2 units was increased to 8. Because of the higher surface sensitivity, ToF-SIMS results showed more CF2 segments at the topmost surface than shown by ADXPS. Copyright © 2006 John Wiley & Sons, Ltd.
Surface and Interface Analysis 06/2006; 38(8):1223 - 1229. · 1.18 Impact Factor
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ABSTRACT: Hemoglobin (Hb) embedded in lactobionic acid (LA) film can give a pair of stable, well-defined, and quasi-reversible cyclic voltammetric peaks, located at the potential characteristic of the heme Fe(III)/Fe(II) redox couple. The formal potential of the protein in LA film was −209 mV. The apparent heterogeneous electron transfer rate constant and the number of protons concomitant per electron during the electron transfer process have been calculated. Hydrogen peroxide could also be catalytically reduced by the protein in LA film. Copyright © 2005 Society of Chemical Industry
Journal of Chemical Technology & Biotechnology 08/2005; 81(1):58 - 61. · 2.17 Impact Factor
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ABSTRACT: Ag-nanoparticles were embedded in the 56GeS2–24Ga2S3–20KBr chalcohalide glasses with varied doses by ion implantation. Ag-nanoparticles were observed in the AFM images of all implanted samples. The third-order optical nonlinearity of Ag-implanted chalcohalide glasses was investigated by the femtosecond Z-scan measurements. The results indicated an enhancement of third-order optical nonlinearity due to the formation of Ag-nanoparticles in glasses. The relation between implanting dose and third-order optical nonlinearity was strongly related to the intrinsic local field and interaction of Ag-nanoparticles.Research Highlights► In this study we prepared Ag-nanoparticle embedded 56GeS2–24Ga2S3–20KBr chalcohalide glasses. ► The influence of Ag nanoparticles on third-order optical nonlinearity was investigated by AFM and Z-Scan method. ► We observed that the larger size with more Ag implanted dose induced the increase of third-order nonlinearity and there was a opium value of ion implanted dose to induce the largest nonlinearity. ► We concluded that the intrinsic local field and interaction of Ag-nanoparticles would decrease the third-order nonlinearity in glass.
Journal of Non-Crystalline Solids 357:2320-2323. · 1.54 Impact Factor
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ABSTRACT: The leakage flow characteristics at the radial clearance between the rotor and the cylinder in a novel synchronal rotary (SR) refrigeration compressor were analyzed, and the oil–refrigerant two-phase leakage flow model was established. The leakage at different temperatures caused by wall velocity and pressure difference was calculated, and their influences on the total leakage were analyzed, respectively. The calculation results indicate that the leakage of the oil–refrigerant mixture decreases firstly and then increases with the increase in the temperature. However, the refrigerant leakage always decreases when the temperature increases. Moreover, the leakage caused by wall velocity has great influence on the total leakage, especially when the radial clearance is small.
International Journal of Refrigeration.
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ABSTRACT: Recent research has thrown considerable light on the history of the domestic sheep, but has not extended to ancient sheep specimens. In the present study, ancient DNA analysis was carried out on eight archaeological sheep remains recovered from Erlitou archaeological site in Henan Province (ca. 2100–1800 B.C.) to explore the genetic structure of ancient sheep and the phylogenetic relationship between ancient and modern sheep. We analyzed the control region sequences and coding regions of mitochondrial DNA from the remains by direct sequencing and restriction fragment length polymorphism analysis, respectively. Our results reveal that all ancient sheep belong to lineage A defined by modern sheep sequences. Phylogenetic analysis shows that neither argali (Ovis ammon) nor urial (Ovis vignei) mtDNA is closely related to Erlitou ancient sheep. In addition, our results suggest that ancient DNA analysis can serve as a powerful tool in tracing prehistoric population movement.
Journal of Archaeological Science.