[show abstract][hide abstract] ABSTRACT: Effectively communicate results from a community exposure study to meet predetermined community priorities, maintaining ethical principles of autonomy, empowerment and justice.
The community established principles for the communications and a plan to inform study participants, community and other stakeholders of results and recommendations in a novel sequence: the "Community-First" communication model.
The communications resulted in positive actions including company sponsored free bottled water, accepted by 77.6% of eligible households. Over 95% of participants in a follow-up survey had made some change to residential water supplies. Serum perfluorooctanoate levels were reduced. Government agencies acted on the results.
The unique communication approach generated workable solutions to the problem investigated, raised community awareness and modified behaviors. Information generated a "free market" of community-level solutions. Each major stakeholder voluntarily adopted a "precautionary principle."
Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine 03/2009; 51(2):146-56. · 1.88 Impact Factor
[show abstract][hide abstract] ABSTRACT: The objective of this study was to determine whether certain biomarkers of toxicity and/or a past diagnosis of liver or thyroid disease were associated with serum perfluorooctanoate concentrations (PFOA) in a community with longstanding environmental exposure to PFOA.
Serum (PFOA), hematologic and biochemical biomarkers, and a questionnaire were administered to 371 residents selected by stratified random sampling and a lottery among volunteers. Median PFOA was 354 ng/mL (interquartile range, 181-571 ng/mL).
No significant positive relationships between serum (PFOA) and liver or renal function tests, cholesterol, thyroid-stimulating hormone, or with red cell indices, white cell, or platelet counts. Mean serum (PFOA) was not increased in those with a history of liver or thyroid disease.
No toxicity from PFOA was demonstrated using the measured end points; other end points need to be addressed.
Journal of Occupational and Environmental Medicine 09/2006; 48(8):771-9. · 1.85 Impact Factor
[show abstract][hide abstract] ABSTRACT: The objective of this study was to determine serum (perfluorooctanoate [PFOA]) in residents near a fluoropolymer production facility: the contributions from air, water, and occupational exposures, personal and dietary habits, and relationships to age and gender.
The authors conducted questionnaire and serum PFOA measurements in a stratified random sample and volunteers residing in locations with the same residential water supply but with higher and lower potential air PFOA exposure.
Serum (PFOA) greatly exceeded general population medians. Occupational exposure from production processes using PFOA and residential water had additive effects; no other occupations contributed. Serum (PFOA) depended on the source of residential drinking water, and not potential air exposure. For public water users, the best-fit model included age, tap water drinks per day, servings of home-grown fruit and vegetables, and carbon filter use.
Residential water source was the primary determinant of serum (PFOA).
Journal of Occupational and Environmental Medicine 09/2006; 48(8):759-70. · 1.85 Impact Factor