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ABSTRACT: Alcoholic men (N = 81) participating in a Veterans Administration inpatient program were classified using four different strategies to describe the extent of familial alcoholism. These classification schemes included: (1) a comparison of alcoholics with no familial alcoholism, parental alcoholism or alcoholism in other relatives, (2) a unilineal-bilineal approach, (3) a multigenerational approach and (4) an approach that quantified the degree of familial alcoholism. Comparisons were made of the performance of the different familial history groups on a series of neuropsychological tests. No differences in cognitive functioning were found using any of the four classification schemes.
Journal of studies on alcohol 10/1987; 48(5):425-9.
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ABSTRACT: This study reports a significantly higher proportion of left-eyedness in patients with remotely acquired right hemisphere brain lesions as compared with patients with recently acquired right hemisphere lesions, as well as patients with left hemisphere lesions, regardless of whether they were recently or remotely acquired. It was determined that this finding could not be attributed to a higher incidence of left-handedness among the patients with remotely acquired right hemisphere lesions. The findings were interpreted in terms of a possible mechanism for adjustment to left field neglect.
International Journal of Neuroscience 01/1986; 28(3-4):285-90. · 0.97 Impact Factor
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ABSTRACT: A series of neuropsychological tests known to be sensitive to the effects of chronic alcoholism was administered to 25 detoxified alcoholic patients with histories of mild head injury and 25 detoxified alcoholics matched for age, race, socioeconomic status, education and drinking history parameters, but without histories of head injury. None of the tests was performed at significantly different levels by the two groups. It was concluded that mild head injury did not compound the effects of chronic alcoholism among these patients, although it was noted that both groups demonstrated the anticipated impairments on the tests. It was also suggested that researchers need not exclude alcoholic subjects with mild head injury histories from studies involving the use of standard neuropsychological tests.
International Journal of Neuroscience 01/1986; 28(3-4):155-62. · 0.97 Impact Factor
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ABSTRACT: A study was conducted of the relationships between psychopathology and neuropsychological deficit in chronic alcoholic patients who had received the Minnesota Multiphasic Personality Inventory (MMPI), the Halstead-Reitan Neuropsychological Test Battery, and the Wechsler Adult Intelligence Scale (WAIS). Classification of the MMPIs by code type resulted in the formation of groups of 10 subjects with normal MMPIs, 19 subjects with MMPI profiles suggestive of depression, and 10 subjects with profiles suggestive of psychosis. Analysis of covariance was performed for various Halstead-Reitan scores; the only significant findings emerged for several of the verbal subtests of the WAIS. The group with psychotic MMPIs did substantially more poorly on these measures than the other groups. It was concluded that depressed alcoholics do not show greater neuropsychological deficit than do individuals with no significant psychopathology other than alcoholism. However, alcoholics with MMPI profiles that suggest psychosis differ from the other groups studied with regard to certain verbal abilities.
Addictive Behaviors 02/1985; 10(4):365-72. · 2.09 Impact Factor
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Journal of Consulting and Clinical Psychology 07/1984; 52(3):383-9. · 4.85 Impact Factor
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ABSTRACT: An investigation was made of whether black alcoholics have a different response to having withdrawal seizures than white alcoholics, in terms of cognitive and other neuropsychological deficits. In a previous study it was found that white alcoholics with histories of withdrawal seizures did not demonstrate neuropsychological differences from white alcoholic patients without such histories. However, the apparently higher incidence of withdrawal seizures among blacks noted during screening of subjects for this study raised the question of whether the consequences of the seizure history might be different among blacks. The Halstead-Reitan Neuropsychological Test Battery was administered to 22 white and 20 black alcoholic inpatients. Half of each group had a history of withdrawal seizures while the other half did not. The results of the study indicated that on several tests, there were significant differences between black patients with and without seizure histories, but that was not the case for the white patients. Various possible causes for this finding are discussed.
Drug and Alcohol Dependence 01/1984; 12(4):349-54. · 3.38 Impact Factor
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Journal of Consulting and Clinical Psychology 11/1982; 50(5):721-6. · 4.85 Impact Factor
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ABSTRACT: The study involved a comparison of the neuropsychological test performance of chronic alcoholic patients with that of patients with localized and nonalcoholic diffuse brain damage. It was hypothesized that if the "right hemisphere" or "frontal lobe" theories of brain localization in alcoholism were correct, the profile obtained by the alcoholic patients would either resemble the profile obtained by the right hemisphere brain damaged patients more than the left hemisphere brain damaged patients. Or alternatively, it would resemble the profile obtained by the patients with frontal lobe brain damage more than the one obtained by the patients with posterior brain damage. In the case of the "right hemisphere" hypothesis, the role of sensory-motor as well as cognitive hemisphere asymmetries was evaluated. The results of the study did not provide strong support for either of the above mentioned hypotheses, but were supportive of the view that brain damage in chronic alcoholism is diffuse, and may reflect premature aging of the brain as a whole.
Addictive Behaviors 02/1982; 7(2):165-75. · 2.09 Impact Factor
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Advances in experimental medicine and biology 02/1980; 126:731-43. · 1.09 Impact Factor
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ABSTRACT: Adolescent sons of alcoholics and nonalcoholics were compared on a battery of intellectual, neuropsychological, personality, and behavioral measures. The former group demonstrated certain neuropsychological deficits in perceptual-motor ability, memory, and language processing. They also had auditory and visual attentional impairments and a lower level of achievement in reading comprehension. In addition, the sons of alcoholics presented a more neurotic personality profile than sons of nonalcoholics. They were, however, less impulsive than the comparison group. More development and familial problems were noted in the alcoholics' offspring as well. The implications of these findings for understanding the causes and consequences of alcoholism are discussed.
Alcoholism Clinical and Experimental Research 8(2):216-22. · 3.34 Impact Factor
