Fasihuddin B. Ahmad

Publications (6)9.59 Total impact

• Article: Organotin(IV) complexes with pyruvic acid phenylhydrazone (HPAPD): Synthesis, spectral characterization and in vitro antibacterial activity

  M. A. Salam, M. A. Affan, Fasihuddin B. Ahmad, Md. Arafath
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  ABSTRACT: The reaction of pyruvic acid phenylhydrazone [HPAPD, (1)] with organotin(IV) chloride(s) leads to the formation of five new organotin(IV) complexes: [MeSnCl2(PAPD)] (2), [BuSnCl2(PAPD)] (3), [PhSnCl2(PAPD)] (4), [Me2SnCl(PAPD)] (5), and [Ph2SnCl(PAPD)] (6). The ligand [HPAPD, (1)] and its organotin(IV) complexes (2–6) have been characterized by CHN analyses, molar conductivity, UV-Vis, FT-IR, 1H, 13C, and 119Sn NMR spectral studies. Spectroscopic data suggested that HPAPD is coordinated to tin(IV) through the carboxylato-O and azomethine-N as a mononegative bidentate chelating agent; the coordination number of tin is five. Compound 1 and its organotin(IV) complexes (2–6) were assayed for in vitro antibacterial activity against Staphylococcus aureus, Bacillus subtilis, Enterobacter aerogenes, Escherichia coli, and Salmonella typhi. The screening results show that 2–6 have better antibacterial activity than 1 and that 6 exhibits significantly better activity than 2–5.
  Journal of Coordination Chemistry 05/2012; 65:1999-2007. · 1.55 Impact Factor
• Article: Synthesis, spectral characterization and crystal structure of a novel trinuclear di-n-butyltin(IV) complex with pyruvic acid-N(4)-cyclohexylthiosemicarbazone (H2PACT).

  M. A. Salam, M. A. Affan, Fasihuddin B. Ahmad, I. Jusoh, Mustaffa B. Shamsuddin, Bohari Yamin, Yang Farina
  Journal of Organometallic Chemistry 01/2012; 696:4202-4206. · 2.38 Impact Factor
• Source

  Available from: Md. Abu Affan

  Article: Synthesis, Characterization and In Vitro Antibacterial Studies of Organotin(IV) Complexes with 2-Hydroxyacetophenone-2-methylphenylthiosemicarbazone (H(2)dampt).

  M A Salam, M A Affan, Ramkrishna Saha, Fasihuddin B Ahmad, Norrihan Sam
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  ABSTRACT: Five new organotin(IV) complexes of 2-hydroxyacetophenone-2-methylphenylthiosemicarbazone [H(2)dampt, (1)] with formula [RSnCl(n-1)(dampt)] (where R = Me, n = 2 (2); R = Bu, n = 2 (3); R = Ph, n = 2 (4); R = Me(2), n = 1 (5); R = Ph(2), n = 1 (6)) have been synthesized by direct reaction of H(2)dampt (1) with organotin(IV) chloride(s) in absolute methanol. The ligand (1) and its organotin(IV) complexes (2-6) were characterized by CHN analyses, molar conductivity, UV-Vis, FT-IR, (1)H, (13)C, and (119)Sn NMR spectral studies. H(2)dampt (1) is newly synthesized and has been structurally characterized by X-ray crystallography. Spectroscopic data suggested that H(2)dampt (1) is coordinated to the tin(IV) atom through the thiolate-S, azomethine-N, and phenoxide-O atoms; the coordination number of tin is five. The in vitro antibacterial activity has been evaluated against Staphylococcus aureus, Enterobacter aerogenes, Escherichia coli, and Salmonella typhi. The screening results have shown that the organotin(IV) complexes (2-6) have better antibacterial activities and have potential as drugs. Furthermore, it has been shown that diphenyltin(IV) derivative (6) exhibits significantly better activity than the other organotin(IV) derivatives (2-5).
  Bioinorganic Chemistry and Applications 01/2012; 2012:698491. · 0.72 Impact Factor
• Article: Synthesis and spectroscopic characterization of organotin(IV) complexes with 2- benzoylpyridine-N(4) cyclohexylthiosemicarbazone (HBPCT): X-ray crystal structure of [PhSnCl2(BPCT)].

  M. A. Affan, M. A. Salam, Fasihuddin B. Ahmad, J. Ismail, Mustaffa B. Shamsuddin, Hapipah M. Ali
  Inorganica Chimica Acta 01/2011; 366:227-232. · 1.85 Impact Factor
• Article: Synthesis and characterization of tin(IV)/organotin(IV) complexes with 2-benzoylpyridine-N(4)-cyclohexylthiosemicarbazone [HBPCT]: X-ray crystal structure of [SnCl3(BPCT)].

  M. A. Salam, M. A. Affan, Fasihuddin B. Ahmad, Ramli B. Hitam, Zoltan Gal, Presly Oliver
  Journal of Coordination Chemistry 01/2011; 64:2409-2418. · 1.55 Impact Factor
• Article: Synthesis, characterization and antibacterial activity of organotin(IV) complexes with 2-hydroxyacetophenone thiocarbohydrazone

  Dayang Norafizan A. Chee, M.A. Affan, Fasihuddin B. Ahmad, M.R. Asaruddin, Norrihan Sam, M.A. Salam, Ahmad Ismail, S.H. Tan
  Journal of Coordination Chemistry 01/2011; 64:4191-4200. · 1.55 Impact Factor