F Essodegui

Publications (2)1.48 Total impact

• Article: [Cushing's syndrome due to a pulmonary carcinoid].

  A Chadli, L Alami, S El Aziz, A Lazghad, H El Ghomari, M Kafih, F Essodegui, L Jabri, A Farouqi, F Marouan
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  ABSTRACT: Cushing paraneoplasic syndrome is a rare cause of hypercorticism. We report a case of 35 year-old man presenting with Cushing's syndrome characterized by severe signs of hypercorticism and hypokalemia. Endocrine investigations were suggestive of an hypercortisolism linked to an ectopic adrenocorticotropic (ACTH) secretion, both at baseline (mean ACTH levels=275 pg/ml, urinary free cortisol excretion=3.898 mmol/24 h) and after pharmacodynamic testing (lack of inhibition of ACTH by dexamethasone). Thoracic tomodensitometric examination revealed a 15 mm tumor corresponding to a neuroendocrine pulmonary carcinoid with positive immunostaining for chromogranin A. Postoperative ACTH measurement was undetectable, plasma cortisol and free urinary cortisol were also decreased after tumor resection suggesting complete tumor removal. This case report illustrates the characteristics of paraneoplasic Cushing syndrome due to ACTH secreting pulmonary neuroendocrine carcinoid.
  Annales d Endocrinologie 07/2006; 67(3):253-8. · 0.74 Impact Factor
• Article: [Primary lymphoma of the thyroid gland].

  N Ibnou Soufyane, A Chadli, H El Ghomari, F Essodegui, F Marouan, A El Farouqi, M R Ababou, M Kafih
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  ABSTRACT: Malignant primary lymphoma of the thyroid gland is a rare disease generally occurring women in the 6(th) or 7(th) decade of life. The principal clinical sign is giant goiter rapidly leading to sings of compression, raising the question of differential diagnosis with anaplastic cancer. The radiological findings in our patient were suggestive of malignancy due to the locoregional invasion. Immunohistochemistry study of the surgical specimen was required to reach the definitive diagnosis of thyroid gland primary lymphoma. Diagnosis of malignant primary lymphoma of the thyroid gland made at the stage of extensive locoregional extension compromises prognosis. Our patient died after one session of chemotherapy.
  Annales d Endocrinologie 07/2002; 63(3):231-4. · 0.74 Impact Factor