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ABSTRACT: The differential diagnosis of ascites is important and is cumbersome .The
present study was conducted to obtain the basic biochemical data in serum and
ascitic fluid of patients with non-malignant ascites; These parameters utilize it for
confirming the underlying causative factors for ascites.The parameters analyzed
were liver enzymes (SGPT, SGOT and ALP), Adenosine deaminase (ADA),
Creatinine, Amylase, Lactate dehydrogenase (LDH), Total proteins and albumin. A
total of 69 patients with non- malignant ascites (55 Males and 14 Females mean
age 49 + 12 years) were studied over a period of one year. Involvement of liver
disease was noted in 47 patients (68%), while the rest of the patients had
peritoneal tuberculosis ( 7 cases – 10% ), nephrotic syndrome ( 9 cases -13% )
and pancreatic ascites ( 6 cases -9%).Biochemical analysis of the results with
Lactate dehydrogenase, proteins and albumin data showed that SAAG (Serum
ascites albumin gradient) is still the best criteria for the differential diagnosis of
ascites.The present study emphasize the SAAG is useful marker for diagnosis of
different ascites , and it will useful for the evaluation and diagnosis of malignant
ascites.
International Journal of Science Innovations and Discoveries. 02/2012; 2(1):72-76.