ABSTRACT: Triumfetta rhomboidea is used ethno medically since ancient times in the treatment of diabetes mellitus. In the present study, the antidiabetic effect of ethanolic extract of Triumfetta rhomboidea was investigated in alloxan induced diabetes rats. Oral administration of ethanolic extract of Triumfetta rhomboidea at the doses of 100, 200, and 400 mg / kg body weight was studied in alloxan induced diabetic rats. The antidiabetic effect of plant extract was increasing with increase in dose. At 400 mg/kg body weight ethanolic extract showed significant decrease in the blood glucose levels. The activity of the plant extracts was comparable with glibenclamide, a well known antidiabetic drug. The result clearly suggests that ethanolic extract of Triumfetta rhomboidea posses’ significant antidiabetic activity.
Research Journal of Pharmaceutical, Biological and Chemical Sciences. 01/2011; 2:721-726.