Publications (16)5.09 Total impact
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Conference Proceeding: Evolving prediction models using genetic algorithm by learning protein sequence data and association rules
30th Pakistan Congress of Zoology (International), Pakistan; 01/2010 -
Article: Developing Protein Structure-Function Relationships in silico
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ABSTRACT: Understanding the biological functions of proteins has been facilitated by the availability of powerful computational tools that greatly help analyzing the complex nature of protein structure-function relationships. The most important challenge faced by functional genomics and proteomics is to elucidate how the three-dimensional structure of a protein may change in vivo, and directly produce a new functional state. The key to understanding functional switches in proteins is to define how post-translational modifications contribute to the structural plasticity of those proteins and how new structures display new functions. Deciphering the protein functional switches regulated by transitory structural and conformational changes will require collaboration between computational scientists and experimentalists. The purpose of this review is to critically discuss the tools presently available in computational biology to approach these questions.Current Organic Chemistry 06/2008; 12(11):957-971. · 3.06 Impact Factor -
Conference Proceeding: Analysis of Phospho.ELM using MAPRes
First International Conference on the Role of Chemistry & Biochemistry in the National Development, University of Balochistan, Quetta, Lahore; 04/2007 -
Conference Proceeding: Rules Required for Phosphorylating Tyrosine Using As A Model Kinase EGFR Utilizing AME
International Symposium on Nano Chemistry: Chemistry, Biochemistry, Molecular Biology & Bioinformatics of Enzymes, The University of Punjab; 09/2006 -
Article: Regulation of apoptosis by histon H2B modifications
Pakistan J. Zool. 03/2006; 38. -
Article: Somatic Cell Cycle Regulation By Histone H3 Modifications: Action of OGT and Kinases
Pakistan J. Zool. 03/2006; 38:137-144. -
Article: Mammalian Epidermal Growth Factor Receptor: Role of Phosphorylation and Glycosylation
Pakistan J. Zool. 03/2006; 38. -
Article: Consensus Sequences as Target for Phosphorylation of Amino Acids in Phosphoproteins: Statistical Computing Analysis
Pakistan J. Zool. 03/2006; 38. -
Article: Regulation of apoptosis by histon H2B modifications
Pakistan journal of zoology 01/2006; 03. · 0.34 Impact Factor -
Article: Mammalian Epidermal Growth Factor Receptor: Role of Phosphorylation and Glycosylation
Pakistan journal of zoology 01/2006; 38:85-92. · 0.34 Impact Factor -
Article: Consensus Sequences as Target for Phosphorylation of Amino Acids in Phosphoproteins: Statistical Computing Analysis
Pakistan journal of zoology 01/2006; 38:55-63. · 0.34 Impact Factor -
Article: Somatic Cell Cycle Regulation By Histone H3 Modifications: Action of OGT and Kinases
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ABSTRACT: Authors: Pakistan J. Zool. 38:137-144, 2006Pakistan journal of zoology 01/2006; 38:137-144. · 0.34 Impact Factor -
Article: Regulation of apoptosis by histon H2B modifications
Pakistan journal of zoology 01/2006; 38:305-312. · 0.34 Impact Factor -
Article: Prediction of Tyr residues involved in autophosphorylation of FLT3 positive leukemias
Pakistan J. Zool. 11/2005; 37. -
Conference Proceeding: Functional Consequences of Phosphorylation and Glycosylation of Oct-2: DNA Binding Transcription Factor
8th Islamic Country Conference on Statistical Sciences at National University of Emerging and Computer Sciences, Lahore, Pakistan; 01/2005 -
Article: Prediction of Tyr residues involved in autophosphorylation of FLT3 positive leukemias
Pakistan journal of zoology 01/2005; 37:289-292. · 0.34 Impact Factor