A M Wang

Boston Children's Hospital, Boston, MA, United States

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Publications (40)119.34 Total impact

  • [Show abstract] [Hide abstract]
    ABSTRACT: The accuracy, rapidity, and reproducibility of color-Doppler-assisted duplex sonography in the diagnosis of significant internal carotid artery stenosis were prospectively evaluated. Only the point of maximal color shift on the color map was used for spectral analysis. When compared with angiography in 60 carotid bifurcations, a measured peak systolic velocity above 1.25 m/sec was 87% accurate in the detection of significant internal carotid artery stenoses greater than 50%. Determination of maximal internal carotid artery velocity was 40% faster with color-Doppler-assisted duplex sonography than with nonassisted duplex ultrasound. The correlation coefficient for interobserver agreement was .90. It increased to .97 when cases of extensive (greater than 1 cm) acoustic shadowing (7% of bifurcations) were excluded. The authors conclude that the color flow map is an accurate and reproducible means of depicting the point of maximal stenosis within the internal carotid artery.
    Radiology 01/1990; 173(3):793-8. · 6.21 Impact Factor
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    ABSTRACT: Osteogenesis imperfecta is a disease of bone formation subdivided into two types, congenita and tarda. It is associated with bony fragility, blue sclerae and abnormality of tooth dentin. Rarely the tarda form is associated with basilar invagination or infolding of the foramen magnum and upper cervical segments into the posterior fossa. This results in hydrocephalus and a spectrum of neurologic dysfunction known as the foramen magnum compression syndrome. Many radiologic methods have been used to evaluate basilar invagination including plain film and CT. We describe a patient with osteogenesis imperfecta tarda examined with CT, with a unique finding of diffuse cerebral atrophy associated with basilar invagination.
    Computerized Medical Imaging and Graphics 07/1989; 13(4):363-7. · 1.50 Impact Factor
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    ABSTRACT: A patient with surgical and neuropathologically confirmed subdural sarcoid granuloma was evaluated using angiography, contrast-enhanced CT and MR. MR images were obtained on a superconducting magnet with T1, intermediate and multi-echo T2 weighted sequences. Review of the 2 prior cases of subdural sarcoid granuloma from the literature evaluated with MR confirm the variable nature of signal intensities of the lesion. MR was most useful in anatomically evaluating the lesion and planning neurosurgical intervention but both CT and MR alone, in this case, did not definitely obviate the other differential diagnosis including meningioma en-plaque, lymphoma, or metastasis.
    Computerized Medical Imaging and Graphics 03/1989; 13(2):199-205. · 1.50 Impact Factor
  • A M Wang, Daniel H. O'Leary
    Journal of Clinical Ultrasound 06/1988; 16(4):262-4. · 0.80 Impact Factor
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    ABSTRACT: A 25-year-old woman presented with a four-year history of progressive right-lower-extremity weakness and atrophy and a left hemisensory deficit was found. Metrizamide-enhanced spinal CT scan showed an intramedullary lesion at the level of T1-T2; this had expanded the cord in fusiform fashion but showed no evidence of a cystic component. Surgical resection was performed and the pathological diagnosis was cavernous hemangioma. Two and one-half years later, her left hemisensory deficit was worsening and a spinal MRI showed high signal intensity mass in the region of the previous surgery consistent with chronic hematoma which was re-evacuated with some improvement in the patient's neurological condition.
    Neuroradiology 02/1988; 30(3):261-4. · 2.37 Impact Factor
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    ABSTRACT: This study was based on 5042 cranial CT examinations in a 2-year period. 19.8% of all cranial CT scans were performed for confirmation or evaluation of clinically suspected stroke. 87% of the clinical diagnoses of stroke were confirmed by CT scan. Intracranial hemorrhage made up a small percentage in this study. The establishment of this diagnosis was a valuable service in the patients' management. Brain tumor may rarely present clinical symptoms mimicking stroke and may have a normal CT initially.
    Neuroradiology 02/1988; 30(1):54-8. · 2.37 Impact Factor
  • Journal of Computer Assisted Tomography 01/1988; 12(3):536-8. · 1.60 Impact Factor
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    ABSTRACT: A technique for CT guided intrathecal contrast material administration via lateral C1-C2 puncture is described as an efficient strategy for evaluation of patients with recent cervical spine injury and quadriplegia.
    Journal of Computer Assisted Tomography 01/1988; 12(4):715-6. · 1.60 Impact Factor
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    ABSTRACT: We present a patient with an intraspinal, high-signal-intensity lesion in the lumbosacral region on T1-weighted magnetic resonance images and a thin line of signal void between this region and the CSF on T2-weighted images. These findings were interpreted initially as representing an extradural spinal lipoma. However, CT revealed an intrathecal collection of iophendylate (Pantopaque), which was subsequently removed via a lumbar puncture. The apparent separation of Pantopaque from the CSF (seen on T2-weighted images and interpreted as the dura) was probably caused by chemical shift artifact, chemical shift contour, and/or CSF motion artifact.
    Journal of Computer Assisted Tomography 01/1988; 12(2):346-8. · 1.60 Impact Factor
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    ABSTRACT: Seven cases of surgically proven intraspinal synovial cysts are reported. Computed tomographic (CT) scans demonstrated a series of low-density masses adjacent to the facet joints; in three cases, a dense rim indicated a calcified wall on the cyst; in one, the wall was partially calcified; and in three the mass appeared to be filled with gas. In all of these cases, there was severe degenerative facet disease at the same level as the synovial cyst. In six patients, the cysts were unilateral, while one was bilateral; seven cysts were located at the level of L4-L5, and one at L3-L4. We conclude from this study that the intraspinal synovial cyst can be identified reliably by the CT scan.
    Computerized Radiology 11/1987; 11(5-6):253-7.
  • Neuroradiology 02/1987; 29(6):590. · 2.37 Impact Factor
  • H A Haykal, A M Wang, A Zamani
    American Journal of Neuroradiology 01/1987; 8(5):911-2. · 3.68 Impact Factor
  • A M Wang, H A Haykal
    American Journal of Neuroradiology 01/1987; 8(2):383-4. · 3.68 Impact Factor
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    ABSTRACT: Listeria monocytogenes is a relatively uncommon pathogen affecting infants or adults with predisposing conditions, such as cirrhosis, diabetes mellitus, autoimmune disease, renal transplants, and solid and lymphoreticular malignancies. Cerebral parenchymal involvement is rare and consists of focal cerebritis, which may progress to abscess formation. This article presents three cases of early Listeria monocytogenes cerebritis, two of which demonstrated ill-defined superficial areas of low attenuation with curvilinear gyral enhancement and one of which demonstrated a deep, low-attenuation lesion with faint surrounding enhancement. Although these findings are nonspecific, their early recognition in the proper clinical setting may help institute early antibiotic therapy, which appears to be successful without surgical intervention.
    American Journal of Neuroradiology 01/1987; 8(2):279-82. · 3.68 Impact Factor
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    ABSTRACT: A carotid-cavernous fistula recurred 16 years after a Hamby procedure. The recurrence was manifested by subarachnoid hemorrhage originating from dilated draining pial veins. The fistula was closed with a balloon catheter introduced through a patent remnant of the cervical carotid artery. Patients who have previously undergone Hamby trapping and embolization should be reassessed for an occult fistula that could predispose them to intracranial bleeding.
    Neurosurgery 11/1986; 19(4):643-8. · 3.03 Impact Factor
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    ABSTRACT: Two cases of surgically proven myxopapillary ependymomas of filum terminale are reported. In both, myelography and metrizamide-enhanced computed tomographic (CT) scans were performed. An intramedullary tumor in the lower thoracic spine, soft-tissue masses in the neural foramina and enlarged bony spinal canal in the lower thoracic and upper lumbar spine were noted in one case and, in the other, an intradural extramedullary tumor at T12-L1 level. Both patients had normal cranial CT scans, and both presented with similar symptoms--low back pain and weakness and paresthesia of leg or legs for up to 3 years' duration. Myelography and metrizamide-enhanced CT scans were performed in order to evaluate disc disease in one patient and spinal stenosis in the other. Ependymoma was an incidental finding, which was then removed by surgical resection. Pathology confirmed the diagnosis.
    Computerized Radiology 09/1986; 10(5):239-43.
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    ABSTRACT: A 28-year-old male was found on CT metrizamide myelography to have an intradural extramedullary tumor at the T8-T9 level. This was seen to compress the spinal cord, and on surgery it was proven to be medulloblastoma. Cranial CT scans disclosed only mild hydrocephalus and minimal anterior displacement of the inferior fourth ventricle on the right. However, magnetic resonance imaging (MRI) which was performed after the spinal surgery demonstrated an inferior cerebellar vermian tumor.
    Computerized Radiology 07/1986; 10(4):161-6.
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    ABSTRACT: A 35-year-old woman developed temporal lobe seizures. Isolated dilatation of the right temporal horn was demonstrated by computed tomography. She was asymptomatic for the next 10 months while on anticonvulsants before severe headaches, vomiting, and mental confusion prompted hospitalization. Both temporal horns were now dilated, there was marked periventricular edema, and cryptococci were cultured from the ventricular fluid. She succumbed after prolonged systemic and intrathecal antifungal therapy, having developed isolation and dilatation of both frontal horns and third and fourth ventricles. Cryptococcal or other fungal meningoencephalitis should be considered in the differential diagnosis of isolated dilatations of the ventricular chambers as noted in the present case.
    Surgical Neurology 04/1986; 25(3):253-60. · 1.67 Impact Factor
  • A M Wang, Amir A. Zamani
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    ABSTRACT: A case of intradural herniation of a thoracic (T12-L1) intervertebral disc is reported. On metrizamide myelography, this lesion resembled an intradural extramedullary tumor with an extradural component. A computed tomographic (CT) scan taken immediately after the myelogram, showed gas in the spinal canal and in the intervertebral disc. In addition, it showed a high-density mass located in the ventral epidural space and also intradurally. The density of this soft-tissue mass was identical to that of the intervertebral disc. CT provided very important information regarding the precise location and probable etiology of the lesion, and the success of surgery.
    Computerized Radiology 03/1986; 10(2-3):115-8.
  • H A Haykal, A M Wang
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    ABSTRACT: Air embolism to the brain occurred several days after insertion of an intraaortic balloon pump. CT demonstrated diffuse hemispheric edema along with two small collections of air in the cerebral hemispheres. Early diagnosis of air embolism to the brain allows early institution of proper therapy in this life-threatening condition.
    Computerized Radiology 01/1986; 10(6):307-9.

Publication Stats

262 Citations
119.34 Total Impact Points


  • 1987–1988
    • Boston Children's Hospital
      • Department of Radiology
      Boston, MA, United States
  • 1986–1988
    • Harvard Medical School
      • Department of Radiology
      Boston, Massachusetts, United States
  • 1985–1988
    • Brigham and Women's Hospital
      • Department of Radiology
      Boston, MA, United States