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ABSTRACT: The present paper is devoted to a comparison between time- resolved fluorescence diffuse optical tomography and continuous wave fluorescence diffuse optical tomography. Both of these techniques aim at reconstructing 3D biodistribution of fluorescent markers embedded in biological tissues. The study is restricted in the time domain to the exploitation of the first three temporal moments of measurements. The temporal benefits in terms of reconstruction have been shown to depend strongly on the optical parameters of the medium investigated as well as the fluorescence lifetime.
Biomedical Imaging: From Nano to Macro, 2008. ISBI 2008. 5th IEEE International Symposium on; 06/2008
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ABSTRACT: This paper is devoted to the Fluorescence Diffuse Optical Tomography. This inverse problem relies on an iterative algorithm based on solutions of partial differential equations. The goal of the paper is to present a multiresolution technique applied to these equations, with the objective of computation complexity reduction. The effectiveness of the approach is then illustrated on a practical example.
Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE; 09/2007
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ABSTRACT: The present paper is devoted to fluorescence diffuse optical tomography by using time resolved signals for the reconstruction of the 3D biodistribution of fluorescent probes embedded in biological tissues. The focus is made on the reconstruction of a methodology for an efficient exploitation of the time resolved data. The study is restricted to the examination of the three first moments of signals acquired in cylindrical geometry. The interest of temporal information upon cw information has been shown especially when only a limited number of views is available.
Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE; 09/2007