Xuan Li

Peking University Third Hospital, Peping, Beijing, China

Are you Xuan Li?

Claim your profile

Publications (8)12.43 Total impact

  • Journal of vascular and interventional radiology: JVIR 11/2013; 24(11):1748-50. DOI:10.1016/j.jvir.2013.05.001 · 2.41 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: To summarize the significance of lumbar punctures in remedy for aneurysmal subarachnoid hemorrhage (aSAH) after embolization. From December 2002 to September 2011, 43 cases of aSAH underwent aneurysm embolization at department of interventional radiology and vascular surgery, Peking University Third Hospital. After the embolization,consecutive lumbar punctures were undertaken everyday, by which we measured proper cerebrospinal fluid pressure and slow drainage of cerebrospinal fluid. In accordance with the lumbar puncture results we determined the control of blood pressure, dehydration and rehydration therapy procedures. Two patients died. Only one patient in the 41 cases of the survived patients developed cerebral vasospasm, cerebral infarction and obstructive hydrocephalus, but by ventriculo-peritoneal shunt, obstructive hydrocephalus was relieved. The remaining 39 patients recovered well. After the mean follow-up of (26.0±5.8) months, no new neurological symptoms were found. Early consecutive lumbar puncture treatment in ASH after embolization is significant.
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 08/2013; 45(4):639-42.
  • [Show abstract] [Hide abstract]
    ABSTRACT: Objective: We report our experience in the treatment of isolated superior mesenteric artery dissection and review the clinical and imaging features reported in the literature. Methods: A retrospective study was conducted of 18 consecutive patients with isolated superior mesenteric artery dissection who presented at the Peking University Third Hospital between September 2008 and May 2012. Their clinical characteristics, including age, sex, medical history, risk factors, symptoms, diagnostic imaging modality, and treatment, were analyzed. Also reviewed were 278 patients with isolated superior mesenteric artery dissection reported in the English language literature. The epidemiology, mechanism, clinical presentation, imaging features, and treatment were discussed. Results: There were 14 men and four women with a mean age of 55.6 years (range, 41-84 years). Four patients were asymptomatic, and 14 presented with acute-onset abdominal pain. The diagnosis was established by contrast-enhanced computed tomography in 17 patients and ultrasound imaging in one patient. All dissections were located at the anterior wall and around the convex curvature of the superior mesenteric artery. The decision to intervene was based on symptoms. Three asymptomatic patients underwent successful conservative management, and one asymptomatic patient with an aneurysmal dilated false lumen underwent endovascular stent placement. For the 14 symptomatic patients, definitive treatment included catheter-directed infusion of a vasodilator in four and stent placement combined with catheter-directed infusion of a vasodilator in 10, of whom one patient underwent hybrid stent placement. No complications or deaths occurred. During the mean 14.9-month (range, 1-40 month) follow-up period, all patients were asymptomatic, and patency of the superior mesenteric artery was demonstrated by contrast-enhanced computed tomography scan. Conclusions: Conservative management can be applied to asymptomatic patients with isolated superior mesenteric artery dissection. For symptomatic patients, stent placement is the definitive treatment if there is no arterial rupture or intestinal necrosis. Self-expanding bare stents that completely cover the curvature of the superior mesenteric artery are recommended. Catheter-directed infusion of a vasodilator can be an effective accessional process after stent placement.
    Journal of vascular surgery: official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter 03/2013; 57(6). DOI:10.1016/j.jvs.2012.11.121 · 3.02 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: To investigate the characteristics of intimal hyperplasia and lovastatin's effects on canine jugular venous prosthesis bypass grafting. In the study, 12 adult mistus dogs were randomly divided into 2 groups: lovastatin group and control group. All the dogs were performed with jugular venous prosthesis bypass grafting (ePTFE, 6 mm in diameter, and 5 cm in length). Four weeks later, all the 12 specimens were harvested. The patency and mural thrombus of grafts were evaluated. The characteristics of intimal hyperplasia were described and measured by HE staining and endothelial nitric oxide synthase (eNOs) immunohistochemical method. The differences between the two groups were compared. Four weeks later, 3 grafts with complete occlusion were found in the two groups separately. Apparent intimal hyperplasia was observed in all the grafts. The neointima of proximal and distal part in lovastatin group were thinner than in control group respectively (proximal P=0.045, distal P=0.040). The endothelial cells were found in the surface of neointima. Newly born vessels could be found in the neointima and the new vessels were more in lovastatin group than in control group (proximal P=0.041, distal P=0.031). At the end of 4 weeks, the intimal hyperplasia with neovascularization was obviously near the anastomosis. Lovastatin showed the ability to inhibit the intimal hyperplasia and promote the neovascularization.
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 10/2012; 44(5):783-7.
  • Jing Yuan Luan · Xuan Li
    [Show abstract] [Hide abstract]
    ABSTRACT: Study Design. Case report.Objective. To describe a unique case of iliac pseudoaneurysm complicated lumbar disc surgery 13 years ago.Summary of Background Data. Major vascular injury is an unusual but life-threatening complication of lumbar disc surgery. If a major vascular injury is unnoticed, the late complications, pseudoaneurysm, may be diagnosed years after primary lumbar disc surgery. Pseudoaneurysm can lead to compression of adjacent neurovascular structures, however, erosion into the adjacent vertebras and presentation with symptoms of nerve root irritation are rare.Methods. The patient was a 54-year-old man presented with pain and numbness in right hip and leg. Examination was normal. Plain X-ray film showed destruction of the fourth and fifth lumbar vertebras. Magnetic resonance scanning showed a retroperitoneal mass eroding into the adjacent vertebras. The mass was primarily misdiagnosed as a neoplasm and a percutaneous needle biopsy was recommended. Before puncture, the CT angiogram confirmed it to be a pseudoaneurysm of left common iliac artery. Then, implantation of a covered stent was undergone.Results. After implantation of a covered stent, the symptoms were relieved immediately. At the 12-month follow-up, the patient remained asymptomatic, and computed tomography angiogram revealed progressive shrinkage of the mass and significant healing of the eroded vertebras.Conclusion. As an unusual complication of lumbar disc surgery, iliac pseudoaneurysm can present with radiating pain even 13-year later, and erode into the adjacent vertebras producing appearances mimicking a tumor. For mass located anterior to vertebras, the percutaneous biopsy must be cautiously, and a contrast-enhanced CT scan is necessary.
    Spine 09/2012; 37(25). DOI:10.1097/BRS.0b013e318272fd3d · 2.30 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Isolated iliac aneurysm is rare and difficult for surgery repair because it locates in the deep pelvis. Endovascular repair is preferred currently, and internal iliac artery is generally embolized in order to avoid the endoleak. Embolization of the internal iliac artery can lead to the complications such as buttock claudication, colon ischaemia and erectile dysfunction. Therefore, the antegrade flow of internal iliac artery should be reserved. One seventy-seven-year-old male patient with isolated left common iliac aneurysm, 30 mm in diameter, was successful endovascular repaired using fenestrated covered stent. At 1-month follow up, the patient was asymptomatic. Computed tomography scan shows the iliac aneurysm was completely excluded, and the antegrade flow of the left common, internal and external iliac arteries were normal.
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 06/2012; 44(3):489-91.
  • [Show abstract] [Hide abstract]
    ABSTRACT: Hepatocellular carcinoma (HCC) is the leading cause of cancer mortality in many countries. Evaluation of new susceptibility risk factors is therefore warranted in order to explore means to improve the survival rate. Here, we report on a novel HCC-related gene known as lysosomal protein transmembrane 4 beta (LAPTM4B) that has two alleles designated LAPTM4B*1 and LAPTM4B*2. Allele *1 differs from allele *2 in that it contains one copy of a 19-bp sequence, whereas this sequence is duplicated in allele *2 in exon 1 of LAPTM4B. In this study, we aimed to investigate the relationship between LAPTM4B allelic variation and HCC susceptibility. The LAPTM4B genotype was analyzed in the blood samples from 102 HCC patients and 135 healthy individuals by PCR. The genotypic distribution of LAPTM4B was analyzed using the chi-squared test. The frequencies of allele *2 were 38.24 and 24.07% in the HCC group and control group, respectively, representing a significant difference between these two groups (P < 0.001). Thus, allele *2 of LAPTM4B appears to be associated with genetic susceptibility of HCC and may therefore be considered as a risk factor.
    Medical Oncology 12/2011; 29(4):2744-9. DOI:10.1007/s12032-011-0139-y · 2.63 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: This study was designed to introduce our novel technique of percutaneous single catheter placement into the hilar bile ducts strictures while fulfilling the purpose of bilateral biliary drainage and stenting. We investigated the efficacy and safety of the technique for the treatment of hilar nonanastomotic biliary strictures. Ten patients who were post-orthotopic liver transplantation between July 2000 and July 2010 were enrolled in this study. Percutaneous Y-configured single-catheter stenting for bilateral bile ducts combined with balloon dilation was designed as the main treatment approach. Technical success rate, clinical indicators, complications, and recurrent rate were analyzed. Technical success rate was 100%. Nine of the ten patients had biochemical normalization, cholangiographic improvement, and clinical symptoms relief. None of them experienced recurrence in a median follow-up of 26 months after completion of therapy and removal of all catheters. Complications were minor and limited to two patients. The one treatment failure underwent a second liver transplantation but died of multiple system organ failure. Percutaneous transhepatic Y-configured single-catheter stenting into the hilar bile ducts is technically feasible. The preliminary trial of this technique combined with traditional PTCD or choledochoscopy for the treatment of hilar biliary strictures after orthotopic liver transplantation appeared to be effective and safe. Yet, further investigation is needed.
    CardioVascular and Interventional Radiology 06/2011; 35(1):184-9. DOI:10.1007/s00270-011-0214-y · 2.07 Impact Factor