Achint Utreja

Publications (2)5.27 Total impact

• Article: Dental extraction as a risk of factor for bisphophonate related osteonecrosis of the jaw in cancer patients : an update

  Achint Utreja, Khalid Almas, Fawad Javed
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  ABSTRACT: Osteonecrosis of the jaw (ONJ) is a complication related to the use of bisphosphonates (BPs). Patients receiving BPs for the treatment of malignancies are at an increased risk of developing bisphosphonate-related ONJ (BRONJ) as compared to patients receiving BPs for the treatment of other disorders such as osteoporosis. Additionally, tooth extractions have been suggested to increase the risk of BRONJ in individuals taking BPs. Objective : To review the role of dental extraction as a risk factor for BRONJ in cancer patients. Materials and Methods : Databases were searched from January 1999 up to and including July 2012 using various combinations of the following keywords: “bisphosphonate”, “osteonecrosis of the jaw”, “cancer”, “oral” and “dental extraction”. Results : Twenty two studies were included. Eighteen studies assessed the relationship between BRONJ and dental extractions in cancer patients, reporting the overall prevalence of BRONJ following extraction in this group as 3.25±2.23%. Four studies did not report a correlation between BRONJ and extractions, and recommended protocols to avoid the complication. Conclusion : There is a plausible relationship between dental extractions and the development of BRONJ in cancer patients. Written informed consent must be obtained prior to dental procedures in patients at risk for developing BRONJ.
  Odonto-stomatologie tropicale = Tropical dental journal 12/2012;
• Source

  Available from: Faisal Qayyum

  Article: Oral health status in children with acute lymphoblastic leukemia.

  Fawad Javed, Achint Utreja, Fernanda O Bello Correa, Mansour Al-Askar, Malik Hudieb, Faisal Qayyum, Abdulaziz Al-Rasheed, Khalid Almas, Khalid Al-Hezaimi
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  ABSTRACT: Leukemia is a malignancy of the bone marrow. Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy and accounts for nearly 75% of all newly diagnosed leukemias and 25% of all malignancies in childhood. The aim of the present study was to review the oral health status in children with ALL. Databases were explored using various combinations of the following keywords: "acute lymphoblastic leukemia", "children", "inflammation", "pediatric", "periodontal disease" and "periodontitis". Oral inflammatory conditions including chelitis, gingivitis, herpetic gingivostomatitis, mucositis, oral candidiasis, periodontitis and ulcerations are common manifestations in children with ALL. RESULTS: Periodontal inflammatory conditions and oral mucositis were reported to be significantly higher in children with ALL as compared to healthy controls. Tooth morphological disorders including agenesis, microdontia, short roots and developmental defects in the enamel and dentin were more often observed in children with ALL as compared to healthy controls. Children with ALL have a reduced salivary flow rate, which makes them more susceptible to dental caries as compared to healthy children. Malocclusion due to microdontia may also trigger temporomandibular joint disorders in children with ALL; however, this relationship needs further investigations. CONCLUSION: Oral inflammatory conditions including mucositis and gingivitis are common in children with ALL as compared to healthy children. Tooth morphological disorders including microdontia and enamel and dentin are common manifestations in children with ALL.
  Critical reviews in oncology/hematology 12/2011; 83(3):303-9. · 5.27 Impact Factor