Jennifer Culhane

Publications (2)6.56 Total impact

• Article: Challenges in defining and classifying the preterm birth syndrome.

  Michael S Kramer, Aris Papageorghiou, Jennifer Culhane, Zulfiqar Bhutta, Robert L Goldenberg, Michael Gravett, Jay D Iams, Agustin Conde-Agudelo, Sarah Waller, Fernando Barros, Hannah Knight, Jose Villar
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  ABSTRACT: In 2009, the Global Alliance to Prevent Prematurity and Stillbirth Conference charged the authors to propose a new comprehensive, consistent, and uniform classification system for preterm birth. This first article reviews issues related to measurement of gestational age, clinical vs etiologic phenotypes, inclusion vs exclusion of multifetal and stillborn infants, and separation vs combination of pathways to preterm birth. The second article proposes answers to the questions raised here, and the third demonstrates how the proposed system might work in practice.
  American journal of obstetrics and gynecology 10/2011; 206(2):108-12. · 3.28 Impact Factor
• Article: The preterm birth syndrome: issues to consider in creating a classification system.

  Robert L Goldenberg, Michael G Gravett, Jay Iams, Aris T Papageorghiou, Sarah A Waller, Michael Kramer, Jennifer Culhane, Fernando Barros, Augustin Conde-Agudelo, Zulfiqar A Bhutta, Hannah E Knight, Jose Villar
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  ABSTRACT: A comprehensive classification system for preterm birth requires expanded gestational boundaries that recognize the early origins of preterm parturition and emphasize fetal maturity over fetal age. Exclusion of stillbirths, pregnancy terminations, and multifetal gestations prevents comprehensive consideration of the potential causes and presentations of preterm birth. Any step in parturition (cervical softening and ripening, decidual-membrane activation, and/or myometrial contractions) may initiate preterm parturition, and should be recorded for every preterm birth, as should the condition of the mother, fetus, newborn, and placenta, before a phenotype is assigned.
  American journal of obstetrics and gynecology 10/2011; 206(2):113-8. · 3.28 Impact Factor