Xin-Fen Xu

Zhejiang University, Hang-hsien, Zhejiang Sheng, China

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Publications (2)1.9 Total impact

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    ABSTRACT: Objective: To explore whether there exist differences in cognitive development between singletons and twins born after in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI). Methods: A total of 566 children were recruited for the study, including 388 children (singletons, n=175; twins, n=213) born after IVF and 178 children (singletons, n=87; twins, n=91) born after ICSI. The cognitive development was assessed using the Chinese-Wechsler Intelligence Scale for Children (C-WISC). Results: For all pre-term offspring, all the intelligence quotient (IQ) items between singletons and twins showed no significant differences no matter if they were born after IVF or ICSI. There was a significant difference in the cognitive development of IVF-conceived full-term singletons and twins. The twins born after IVF obtained significantly lower scores than the singletons in verbal IQ (containing information, picture & vocabulary, arithmetic, picture completion, comprehension, and language), performance IQ (containing maze, visual analysis, object assembly, and performance), and full scale IQ (P
    Journal of Zhejiang University SCIENCE B 01/2014; 15(1):51-7. DOI:10.1631/jzus.B1300229 · 1.29 Impact Factor
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    ABSTRACT: We compared the social adjustment among Chinese children born after intracytoplasmic sperm injection (ICSI) vs those after in vitro fertilisation (IVF) and identify factors related to the adjustment. The social adaptation of 86 ICSI and 165 IVF conceived children of 4-6 years of age was assessed using the Infants-Junior Middle School Students' Social-Life Abilities Scale. There was no significant difference between the ICSI and IVF-conceived groups on the item of communication, self-dependence, locomotion, work skills, socialisation, self-management and total scores. Compared with routine IVF, ICSI does no harm to the social adaptation of children conceived through this technology.
    Journal of Obstetrics and Gynaecology 11/2011; 31(8):751-3. DOI:10.3109/01443615.2011.606937 · 0.60 Impact Factor

Publication Stats

4 Citations
1.90 Total Impact Points


  • 2011–2014
    • Zhejiang University
      • School of Medicine
      Hang-hsien, Zhejiang Sheng, China