Publications (2)2.28 Total impact
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Article: Polymorphism of the growth hormone gene and its association with growth traits in Boer goat bucks.
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ABSTRACT: In the present study, the polymorphism of growth hormone (GH) gene was analyzed as a genetic marker candidate for growth traits in Boer goat bucks. Two single nucleotide polymorphisms (SNPs) - A781G (Ser/Gly35) and A1575G (Leu147), were identified by GH gene sequencing and PCR-RFLP (polymerase chain reaction-restriction fragment length polymorphism) analysis. AA genotype resulted in a significant decrease in birth chest girth (P=0.03) and weaning weight (P=0.014) comparing to AB genotype, while CC genotype contributed to weaning height (P=0.04) greater than CD genotype. When in combination, AACD genotype was undesired for lower scores in a series of growth traits including body weight, length, height, and chest girth at birth and weaning, as well as the pre-weaning daily gain and body weight at age of 11 months. These results indicate that new molecular markers associated with caprine growth traits can be used in MAS (marker-assisted selection) in Boer goat bucks.Meat Science 02/2009; 81(2):391-5. · 2.28 Impact Factor -
Article: Polymorphism of the growth hormone gene and its association with growth traits in Boer goat bucks
[show abstract] [hide abstract]
ABSTRACT: In the present study, the polymorphism of growth hormone (GH) gene was analyzed as a genetic marker candidate for growth traits in Boer goat bucks. Two single nucleotide polymorphisms (SNPs) – A781G (Ser/Gly35) and A1575G (Leu147), were identified by GH gene sequencing and PCR–RFLP (polymerase chain reaction–restriction fragment length polymorphism) analysis. AA genotype resulted in a significant decrease in birth chest girth (P = 0.03) and weaning weight (P = 0.014) comparing to AB genotype, while CC genotype contributed to weaning height (P = 0.04) greater than CD genotype. When in combination, AACD genotype was undesired for lower scores in a series of growth traits including body weight, length, height, and chest girth at birth and weaning, as well as the pre-weaning daily gain and body weight at age of 11 months. These results indicate that new molecular markers associated with caprine growth traits can be used in MAS (marker-assisted selection) in Boer goat bucks.Meat Science.