Samanta Blattes da Rocha

Instituto de Neurologia de Curitiba, Curityba, Paraná, Brazil

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Publications (7)4.57 Total impact

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    ABSTRACT: Refractory epilepsy accounts for 20 to 30% of epilepsy cases and remains a challenge for neurologists. Vagus nerve stimulation (VNS) is an option for palliative treatment. It was to study the efficacy and tolerability of VNS in patients implanted with a stimulator at the Curitiba Institute of Neurology (INC). A case study of six patients with refractory epilepsy submitted to a VNS procedure at the INC in the last four years was described and discussed. Mean age at time of implantation was 29 years. Mean follow-up was 26.6 months. Seizure frequency decreased in all patients (40-50% (n=2) and >80% (n=4)). Three patients no longer required frequent hospitalizations. Two patients previously restricted to wheelchairs started to walk, probably because of improved mood. In this population, VNS proved to be a sound therapeutic option for treating refractory epilepsy.
    Arquivos de neuro-psiquiatria 01/2013; 71(1):25-30. · 0.55 Impact Factor
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    ABSTRACT: Catastrophic epileptic encephalopathies in children comprise devastating conditions that features cerebral dysfunction in association with refractory epileptic seizures. The diagnosis is based on the clinical findings, on magnetic resonance imaging (MRI) of the brain and on electroencephalographic findings. For these conditions, surgery remains essential for attaining seizure control. We report two cases of 5-year-old girls. The first one had a diagnosis of Rasmussen’s syndrome. The second one had a large porencephalic cyst secondary to perinatal cerebral ischemia. Despite trials of anticonvulsants, both patients deteriorated, and a functional hemispherectomy guided by neuronavigation was indicated and performed, with low morbidity and excellent seizure control. The neuronavigation proved to be a valuable guidance tool in performing the functional hemispherectomy, making the disconnections more accurate, and thus decreasing the surgical time and blood loss.
    Journal of Epilepsy and Clinical Neurophysiology 12/2010; 17(3):93-99.
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    ABSTRACT: Syncope is a condition often misdiagnosed as epileptic seizures. However, the differential diagnosis between both conditions can be quite difficult, even for well-trained physicians. Four cases of epilepsy and/or syncope are reported, to exemplify this situation. Each case is discussed individually, and the confounding factors are analyzed.
    Arquivos de Neuro-Psiquiatria 10/2005; 63(3A):597-600. · 1.01 Impact Factor
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    ABSTRACT: Forty-three patients with epilepsy resistant to drug therapy were submitted to temporal lobe epilepsy surgery at the Instituto de Neurologia de Curitiba, from 1998 to 2003. Thirty-nine patients (90.6%) had mesial temporal sclerosis, and four had brain tumors. According to Engel's rating, 83.7% from 37 patients with complete postoperative evaluation were classified as Class I (free of disabling seizure). Postoperative complications (18.6%) were evaluated, with one case of surgical wound infection, one case of hydrocephalus, one case of cerebrospinal fluid fistula, two cases of transient palsy of the trochlear nerve and one case of transient hemiparesis. No death related to epilepsy surgery was found in our study.
    Arquivos de Neuro-Psiquiatria 10/2005; 63(3A):618-24. · 1.01 Impact Factor
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    ABSTRACT: Partial and generalized tonic-clonic reflex seizures related to hot water bathing have been described as temperature-related. We describe three cases of bathing epilepsy: a 28 year-old white male and a 30 year-old white female with spells triggered either by warm or hot water, and a 32 year-old female with spells triggered by hot water. The later two of the three cases presented localized epilepsy and a familial history of epilepsy. A complex tactile stimuli might play the most relevant role on seizure triggering, as well as water temperature with an additive effect over cutaneous stimulation.
    Arquivos de Neuro-Psiquiatria 07/2005; 63(2B):399-401. · 1.01 Impact Factor
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    ABSTRACT: RESUMO Introdução: O teste de Wada ® continua sendo um exame freqüentemente utilizado, para a avaliação quali-tativa e quantitativa da lateralidade das funções de linguagem e das funções de memória verbal, e do possí-vel déficit residual, uma vez que simula o efeito da cirurgia na investigação pré-operatória de candidatos a lobectomia temporal. No Brasil, há consideráveis dificuldades impostas pelas autoridades sanitárias para obtenção do Amytal ® (amobarbital sódico). Objetivos: Descrever o protocolo do teste de Wada realizado com Brevital ® (methoexital sódico) em dois candidatos a lobectomia temporal, comentar sua eficácia e suas diferenças em relação ao realizado com o Amytal ® . Métodos: Relatamos o uso do Brevital ® em dois pacien-tes submetidos a determinação da lateralidade da linguagem e da memória através de protocolo adaptado para tal. Resultados: O Brevital ® , um anestésico de ação curta, mostrou-se eficiente em ambos os casos como substituto ao Amytal ® . Conclusões: O Brevital ® pode ser utilizado no Brasil para a realização do teste de Wada, com a vantagem de possibilitar um exame mais breve, assim como uma investigação abrangente das funções de memória. Unitermos: teste de Wada, amobarbital sódico, methohexital sódico, dominância hemisférica, lobectomia temporal. ABSTRACT The sodium methohexital (Brevital ®) in Wada's test – report of two cases Introduction: The Wada's test is still being frequently used at epilepsy surgery centers in temporal lobectomy candidates to evaluate the extent, quality and lateralization of memory functions, and to estimate residual deficit, since it simulates the effects of the surgery. In Brazil, Amytal ® is very difficult to be obtained due to local regulatory barriers. Objectives: To describe the Wada procedure carried out with Brevital ® in two temporal lobectomy candidates, and to comment on its efficacy and differences regarding the Wada procedure carried out with Amytal ® . Methods: The Wada procedure carried out with Brevital ® in two patients in order to determine the laterality of language and memory through an adjusted protocol is reported. Results: We report two cases submitted to the Wada test with sodium methohexital. Results: Brevital ® , a short-lasting anesthetic, showed good results as an Amytal ® substitute. Conclusion: Brevital ® may be used in Brazil for Wada tests, with the additional advantages of allowing a shorter procedure, as well as a comprehensive assessment of memory.
    Journal of Epilepsy and Clinical Neurophysiology 01/2005; 11(2).
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    ABSTRACT: Functional magnetic resonance imaging (fMRI) is a technique for detecting minimal changes in brain perfusion and oxygenation secondary to neuronal activation. Its application in the pre-surgical evaluation of epileptic patients with temporal mesial sclerosis is currently being under investigation in several centers. This study aims to describe an activation paradigm for the evaluation of language and memory functions, as an alternative to the worldwide used Wada test, which is an invasive procedure. In order to propose a paradigm adapted to the Portuguese language, we report our experience in determining the dominant cerebral area for language through fMRI with a verbal fluency task. The results of the fMRI from 19 patients studied in Curitiba in a period of approximately two years were studied. Sixteen of them presented with left hemispheric cerebral language dominance. In five patients, results from fMRI and Wada test could be compared and agreed in localization. Our results reinforce the view that fMRI may become an essential tool for medical practice, perhaps for the determination of eloquent areas in the evaluation of candidates for epilepsy surgery.
    Arquivos de Neuro-Psiquiatria 04/2004; 62(1):61-7. · 1.01 Impact Factor

Publication Stats

8 Citations
4.57 Total Impact Points

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  • 2004–2005
    • Instituto de Neurologia de Curitiba
      Curityba, Paraná, Brazil