Nurziana Ngah

International Islamic University Malaysia, Kuala Lumpor, Kuala Lumpur, Malaysia

Are you Nurziana Ngah?

Claim your profile

Publications (43)11.26 Total impact

  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: In the title compound, C10H11FN3O3S, the 2-fluoro-benzoyl and proponic acid groups maintain a trans-cis conformation with respect to the thiono C=S bond across their C-N bonds. The propionic acid group adopts an anti conformation about the C-C bond, with an N-C-C-C torsion angle of 173.8 (2)°. The amino groups are involved in the formation of intra-molecular N-H⋯O and N-H⋯F hydrogen bonds. In the crystal, pairs of O-H⋯O hydrogen bonds link mol-ecules into inversion dimers.
    Acta Crystallographica Section E Structure Reports Online 06/2014; 70(Pt 6):o705. · 0.35 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: To investigate the potential of Musa x paradisiaca (M. x paradisiaca) flower extracts in promoting milk production of lactating rats and its effects on growth of the suckling pups. Galactagogue activity was evaluated in terms of quantity of milk produced from the rats treated with petroleum ether, ethanol or water extracts of the flower. Lactating rats (n = 5) of Spraque Dawley with six pups each were administered with the extracts in the amount of 500 mg/kg body weight, while the control rats were given an equivalent amount of distilled water. The rats were daily administered via oral feeding starting from Day 5 until Day 14 and the performance of milk production was measured along the experimental period by weight-suckle-weight method. Results were statistically analyzed using SPSS by means of ANOVA at 0.05 and was expressed as their mean?standard deviation. The rates of pups' growth were measured as the weight gain along the experimental period. The rats treated with aqueous extract produced higher milk than control and ethanol groups. Aqueous extract was identified to increase milk production by 25%, while petroleum ether extract by 18%. The mean of yields produced by the rats during suckling period for aqueous, petroleum ether, ethanol and control were 4.62±2.45, 4.37±1.93, 3.65±1.89 and 3.69±1.79, respectively. Growth rates of pups for the rats treated with control, aqueous, ethanol extract and petroleum ether were (1.85±0.49), (1.78±0.56), (1.65±0.46) and (1.56±0.42) g/pup, respectively. The present study reveals the potential of M. x paradisiaca flower to enhance milk production of nursing mothers which could be exploited for commercialization of the isolated extract.
    Asian Pacific Journal of Tropical Medicine 11/2012; 5(11):882-6. · 0.50 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: In the title compound, C(14)H(18)N(2)O(3), the carb-oxy-lic group is tilted by 12.00 (4)° with respect to the mean plane throught the benzimidazole ring system. The alcohol and carboxyl hydroxy groups are involved in intermolecular O-H⋯O and O-H⋯N hydrogen bonds, forming a two-dimensional network extending parallel the ab plane. The network is further stabilized by weak C-H⋯O inter-actions. The sec-butyl group is disordered over two sets of sites with refined occupancies of 0.484 (4) and 0.516 (4).
    Acta Crystallographica Section E Structure Reports Online 07/2012; 68(Pt 7):o1995. · 0.35 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: The asymmetric unit of the title compound, C(11)H(12)ClN(3)O(3)S, contains two independent mol-ecules with different conformations in which the benzene ring and the thio-urea fragment form dihedral angles of 87.28 (12) and 66.44 (10)°. The O atom of the thio-amide group is involved in bifurcated N-H⋯O intra- and inter-molecular hydrogen bonding; the latter inter-action links the independent mol-ecules into a dimer. In the crystal, N-H⋯S inter-actions link the mol-ecules into chains propagating along the c axis.
    Acta Crystallographica Section E Structure Reports Online 06/2012; 68(Pt 6):o1801. · 0.35 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: The asymmetric unit of the title compound, C11H12ClN3O3S, contains two independent mol­ecules with different conformations in which the benzene ring and the thio­urea fragment form dihedral angles of 87.28 (12) and 66.44 (10)°. The O atom of the thio­amide group is involved in bifurcated N—H⋯O intra- and inter­molecular hydrogen bonding; the latter inter­action links the independent mol­ecules into a dimer. In the crystal, N—H⋯S inter­actions link the mol­ecules into chains propagating along the c axis.
    Acta Crystallographica Section E Structure Reports Online 05/2012; 68(6). · 0.35 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: The benzene rings of the biphenyl group in the title compound, C(20)H(14)ClN(3)O(3)S, are nearly coplanar [maximum deviation = 0.20 (3) Å]. The mean plane of the biphenyl group forms a dihedral angle of 5.24 (7)° with the aromatic ring of the nitro-chloro-benzene group. Intra-molecular N-H⋯Cl, N-H⋯O and C-H⋯S hydrogen bonds stabilize the cis-trans conformation of the mol-ecule. In the crystal, mol-ecules are linked by C-H⋯O and C-H⋯S hydrogen bonds into mutually inter-woven corrugated layers parallel to (10-2).
    Acta Crystallographica Section E Structure Reports Online 05/2012; 68(Pt 5):o1485. · 0.35 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: The asymmetric unit of the title compound, C(11)H(12)Cl(2)N(2)OS, contains two crystallographically independent mol-ecules with different conformations: the benzene ring and the thio-urea fragment form dihedral angles of 74.32 (11) and 89.39 (11)°. One amino group in each mol-ecule is involved in intra-molecular N-H⋯O and inter-molecular N-H⋯O hydrogen bonding: the latter links pairs of independent mol-ecules into dimers. In the crystal, weak N-H⋯S inter-actions link these dimers into chains propagating along the c axis.
    Acta Crystallographica Section E Structure Reports Online 05/2012; 68(Pt 5):o1536. · 0.35 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: The asymmetric unit of the title compound, C11H12Cl2N2OS, contains two crystallographically independent mol­ecules with different conformations: the benzene ring and the thio­urea fragment form dihedral angles of 74.32 (11) and 89.39 (11)°. One amino group in each mol­ecule is involved in intra­molecular N—H⋯O and inter­molecular N—H⋯O hydrogen bonding: the latter links pairs of independent mol­ecules into dimers. In the crystal, weak N—H⋯S inter­actions link these dimers into chains propagating along the c axis.
    Acta Crystallographica Section E Structure Reports Online 04/2012; 68(5). · 0.35 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: In the title mol-ecule, C(19)H(20)N(2)O(4)·H(2)O, the benzimidazole ring system is essentially planar [maximum deviation = 0.013 (11) Å] and is inclined to the 4-meth-oxy-phenyl ring by 30.98 (5)°. In the crystal, O-H⋯O and O-H⋯N hydrogen bonds involving the water mol-ecule link neighbouring mol-ecules, forming a two-dimensional network lying parallel to the bc plane. There are also C-H⋯π and π-π inter-actions present. The latter involve inversion-related benzimidazole rings with centroid-centroid distances of 3.5552 (8) and 3.7466 (8) Å.
    Acta Crystallographica Section E Structure Reports Online 02/2012; 68(Pt 2):o421. · 0.35 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: In the crystal structure of the title compound, C(15)H(20)N(2)O(3)S, the hy-droxy group is involved in the formation of O-H⋯N hydrogen bonds, which link two mol-ecules into a centrosymmetric dimer. Weak C-H⋯O hydrogen bonds further link these dimers into chains propagating along the a axis. The crystal packing exhibits π-π inter-actions between the five- and six-membered rings of neighbouring mol-ecules [centroid-centroid distance = 3.819 (2) Å] and short inter-molecular S⋯S contacts of 3.495 (1) Å.
    Acta Crystallographica Section E Structure Reports Online 01/2012; 68(Pt 1):o197-8. · 0.35 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: In the title compound, C(18)H(20)BrNO(3), the oxazolidine ring adopts an envelope conformation with the N atom at the flap position. The mean plane of oxazolidine ring makes dihedral angles of 82.96 (13) and 70.97 (12)°, respectively, with the phenyl and benzene rings. In the crystal, adjacent mol-ecules are connected via O-H⋯O and C-H⋯O hydrogen bonds and C-H⋯π inter-actions into a zigzag chain along the b axis.
    Acta Crystallographica Section E Structure Reports Online 01/2012; 68(Pt 1):o35-6. · 0.35 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: In the title compound, C(21)H(24)N(2)O(3), the mean planes of the benzene ring and the benzimidazole ring system form a dihedral angle of 69.94 (7)°. The ethyl group atoms of the ethano-ate fragment are disordered over two sets of sites, with refined occupancies of 0.742 (6) and 0.258 (6). In the crystal, there are weak C-H⋯N hydrogen bonds which connect mol-ecules into chains along the b axis. A weak inter-molecular C-H⋯π inter-action is also observed.
    Acta Crystallographica Section E Structure Reports Online 12/2011; 67(Pt 12):o3231-2. · 0.35 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: In the title compound, C(20)H(21)BrN(2)O(2), the bromo-phenyl ring is twisted by 40.13 (8)° from the benzimidazole mean plane and the Br atom deviates by 0.753 (1) Å from that plane. The sec-butyl group is disordered over two conformations in a 0.898 (5):0.102 (5) ratio. In the crystal, mol-ecules related by translation along [[Formula: see text]10] are linked into chains via weak C-H⋯Br hydrogen bonds.
    Acta Crystallographica Section E Structure Reports Online 12/2011; 67(Pt 12):o3453. · 0.35 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: In the title compound, C(20)H(21)FN(2)O(2), the benzene ring and the benzimidazole ring system are inclined at a dihedral angle of 44.40 (9)°. In the crystal, mol-ecules are linked by inter-molecular C-H⋯O hydrogen bonds, forming a zigzag chain along the b-axis direction. An intra-molecular C-H⋯π inter-action is also observed.
    Acta Crystallographica Section E Structure Reports Online 11/2011; 67(Pt 11):o2938. · 0.35 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: In the title compound, C(15)H(20)N(2)O(3), the benzimidazole ring is essentially planar, with a maximum deviation from the mean plane of 0.012 (1) Å. The crystal structure is stabilized by inter-molecular O-H⋯N hydrogen bonds, forming centrosymmetric dimers, which are connected in the [100] direction through weak C-H⋯O contacts.
    Acta Crystallographica Section E Structure Reports Online 10/2011; 67(Pt 10):o2704. · 0.35 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: In the title compound, C14H12N2O2S, the benzoyl and 3-hydroxyphenyl fragments adopt trans–cis positions with respect to the S atom across their C—N bonds. The dihedral angle between the 3-hydroxyphenyl and N2CS thiourea groups is 72.09 (8)°. The crystal structure is stabilized by O—H...S and N—H...S hydrogen bonds, forming a polymeric chain along the c axis.
    Acta Crystallographica Section E Structure Reports Online 05/2007; 63(5). · 0.35 Impact Factor
  • Acta Crystallographica Section E-structure Reports Online - ACTA CRYSTALLOGR E-STRUCT REP. 01/2007; 63(5).
  • [Show abstract] [Hide abstract]
    ABSTRACT: In the title compound, C13H14N2O3S·H2O, the benzoyl group lies out of the plane of the N2CS thiourea unit, having a Ccarbon­yl—N—C—S torsion angle of 119.4 (4)°. The crystal structure is stabilized by N—H⋯O, O—H⋯O, C—H⋯O and C—H⋯S inter­molecular hydrogen bonds, forming a two-dimensional network.
    Acta Crystallographica Section E Structure Reports Online 10/2006; 62(10). · 0.35 Impact Factor
  • Nurziana Ngah, Najiha Darman, Bohari M. Yamin
    Acta Crystallographica Section E Structure Reports Online 08/2006; 62(8). · 0.35 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Mol­ecules of the title compound, C14H18N2O4S, are linked into a linear chain, which propagates along the a axis of the triclinic unit cell through inter­molecular hydrogen bonding between the carboxyl group and the thioxo S atom.
    Acta Crystallographica Section E Structure Reports Online 05/2006; 62(5). · 0.35 Impact Factor

Publication Stats

10 Citations
11.26 Total Impact Points

Institutions

  • 2011–2014
    • International Islamic University Malaysia
      Kuala Lumpor, Kuala Lumpur, Malaysia
  • 2012
    • University of Science Malaysia
      • School of Pharmaceutical Sciences
      Nibong Tepal, Pulau Pinang, Malaysia
  • 2005–2007
    • National University of Malaysia
      • School of Chemical Sciences and Food Technology
      Putrajaya, Putrajaya, Malaysia
    • International Union of Toxicology
      Reston, Virginia, United States