A De Bonilla-Damiá

Publications (2)0 Total impact

• Article: Lymphatic drainage in prostate carcinoma assessed by lymphoscintigraphy and SPECT/CT: its importance for the sentinel node procedure.

  A de Bonilla-Damiá, O Roberto Brouwer, W Meinhardt, R A Valdés-Olmos
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  ABSTRACT: The goal was to evaluate the sentinel node procedure in relation to different pathways of lymphatic drainage and the areas of pelvic lymphadenectomy in patients with prostate cancer assessed by lymphoscintigraphy and SPECT/CT study. Eighteen patients with prostate cancer of intermediate prognosis were injected with 240 MBq of (99m)Tc-nanocolloid in the peripheral zone of each quadrant of the prostate, guided by transrectal ultrasonography. Tracer administration was also controlled with a portable gamma camera to assure that there was no diffusion outside the prostate. The injection was followed by planar imaging at 15 min. and 2 h, performing a SPECT/CT study at 2 h. with 2 mm slices. On the same day, a laparoscopic sentinel node lymphadenectomy assisted by a gamma probe and a portable gamma camera was performed. A total of 55 sentinel lymph nodes (SLNs) were visualized. In 17/18 of patients (94%) SLNs were observed outside the obturator region. Twenty SLNs (36%) were observed along the external iliac artery, 14 in the obturator fossa (25.4%), 6 in internal iliac area (11%) and 4 in common iliac region (7.2%). Three SLNs were visualized in presacral (5.4%), paraaortic (5.4%), and pararectal areas (5.4%) and two in paravesical region (3.6%). SLN metastases were found in 6 patients (33%), and in one of them, a SLN located along the common iliac artery, was the only one with metastases. Lymphatic drainage from the prostate has high individual variability, and direct drainage outside the pelvic area is observed frequently. With the SLN procedure, SLNs outside the routine area of lymphadenectomy can also be sampled to stage the patient more accurately.
  Revista española de medicina nuclear e imagen molecular. 11/2011; 31(2):66-70.
• Source

  Available from: elsevier.pt

  Article: [Detection by SPECT-CT scan with (99m)Tc-(V) DMSA of bone metastases in patient with medullary thyroid cancer].

  A De Bonilla-Damiá, C Calvo-Morón, P A De La Riva-Pérez, R Iglesias-Jerez, M Molina-Mora, J Castro-Montaño
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  ABSTRACT: Multiple endocrine neoplasia syndrome, type 2B (MEN 2B), is a rare entity characterized by the presence of medullary thyroid cancer in 100% of the cases. The phenotype of this syndrome consists in the presence of marfanoid features and mucocutaneous neuromas. We describe the case of a male patient with MEN 2B syndrome who was diagnosed with medullary thyroid cancer after lung metastases was found. We analyze the role of DMSA-V and the new hybrid SPECT-CT scan systems in the extension study and monitoring of medullary thyroid cancer.
  Revista española de medicina nuclear. 03/2011; 30(6):365-7.