[show abstract][hide abstract] ABSTRACT: We evaluated treatment decisions and antimicrobial use related to 2 testing algorithms for Clostridium difficile infection (CDI). Our findings suggest that a 2-step testing algorithm using rapid polymerase chain reaction confirmatory testing leads to decreased unnecessary anti-CDI antimicrobial use. In addition, a significant proportion of patients with confirmed CDI were not treated according to recommended guidelines.
Infection Control and Hospital Epidemiology 11/2011; 32(11):1133-6. · 4.02 Impact Factor