Publications (1)2.65 Total impact
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Article: Synthesis and antibacterial activity of N4-mono alkyl derivatives of novel glycopeptide LYV07ww01.
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ABSTRACT: Thirty-one N(4)-mono alkyl derivatives of novel glycopeptide LYV07ww01 were synthesized by the reductive alkylation and their in vitro antibacterial activity was tested. The benzyl derivatives showed potent activity, especially against vancomycin-resistant enterococci and penicillin-resistant Streptococcus pneumoniae.Bioorganic & medicinal chemistry letters 11/2011; 21(22):6732-8. · 2.65 Impact Factor