Anne Marie Liles

Auburn University, Auburn, Alabama, United States

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Publications (10)9.05 Total impact

  • Anne Marie Liles
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    ABSTRACT: The kidney plays a major role in pharmacokinetics and pharmacodynamics of drugs; therefore, medication errors can result from failure to properly adjust medications in patients with CKD. It is the responsibility of all health-care providers to work collectively when reviewing medications, initiating new medications, and adjusting doses of current medications. Awareness of appropriate dosing recommendations can significantly decrease medication error–associated morbidity, mortality, and cost.
    Advances in Chronic Kidney Disease 07/2014; 21(4):349–354. DOI:10.1053/j.ackd.2014.03.014 · 1.94 Impact Factor
  • Kim Zuber, Anne Marie Liles, Jane Davis
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    ABSTRACT: Appropriate dosage adjustments for patients with chronic kidney disease (CKD) are critical for patient safety. This article reviews adjustments for common antidiabetic, antibiotic, analgesic, and antithrombotic medications, as well as important patient teaching information for over-the-counter (OTC) medications.
    JAAPA: official journal of the American Academy of Physician Assistants 10/2013; 26(10):19-25. DOI:10.1097/01.JAA.0000435257.26357.a8
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    ABSTRACT: To compare a numeric grade-based rubric, previously developed by the Auburn University, Harrison School of Pharmacy for assessing fourth-year Doctor of Pharmacy student professional seminar presentations, to a newly developed pass/fail rubric.MethodsA research group was assembled for this study that consisted of five faculty members and the school's assessment director. The research group reviewed a random sampling of 25% (n = 32) of the 2011 graduating class's seminar presentations using the newly developed pass/fail rubric. Of those selected, the seminar presentation was viewed via digital or DVD recordings and graded by three members of the research group. These assessments were then compared to the actual grade received with the old, numeric-based rubric in 2010–2011. The Wilcoxon matched-pairs signed-ranks test for paired comparisons was employed to compare the scores with the old and new grading rubrics.ResultsNone of the students in the sample failed the professional seminar with utilization of the old, numeric-based rubric. However, the failure rate increased significantly [65.6% (n = 21), p<0.001] with utilization of the new pass/fail rubric. Overall, the strongest performance categories with the new rubric were Delivery (34% received highest distinction and 6% failed) and Printed and Audiovisual Materials (28% received highest distinction and 9% failed). The weakest areas of performance with the new rubric were Summary (50% failure) and Seminar Content (44% failure).Conclusions Utilization of the new pass/fail rubric provides a more rigorous system of grading student presentations than the old numeric-based rubric.
    Currents in Pharmacy Teaching and Learning 07/2013; 5(4):288-294. DOI:10.1016/j.cptl.2013.02.002
  • Anne Marie Liles
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    ABSTRACT: The evidence evaluating the efficacy of i.v. versus oral iron for the treatment of iron deficiency in non-hemodialysis-dependent patients with chronic kidney disease (CKD) is reviewed. Although erythropoiesis-stimulating agents (ESAs) are the mainstay of anemia treatment, concomitant iron supplementation is often required. Patients with CKD are at risk for developing iron deficiency due to frequent blood testing, decreased dietary intake, inflammation, decreased gastrointestinal absorption, the use of phosphate binders, hemodialysis, and treatment with ESAs. Seven randomized, controlled trials compared i.v. and oral iron in this population, six in patients treated with ESAs and one in patients not receiving ESAs. Two studies found no difference between i.v. and oral iron. An additional study found the two formulations to be equivalent when evaluating ESA dosage requirements. All studies found i.v. iron to be superior in increasing ferritin and transferrin saturation (TSAT) levels. Five of the studies compared baseline laboratory values for patients treated with i.v. and oral iron; all of these found oral iron to significantly increase hemoglobin, ferritin, or TSAT levels. Only one trial found a significant decrease from baseline in ferritin and TSAT for oral iron. Interpretation of the results of these studies is limited by several factors, the most significant of which is a short study duration, ranging from 21 days to six months. Published evidence does not support the use of i.v. iron over oral iron to treat deficiencies in non-hemodialysis-dependent patients with CKD. While studies found that i.v. iron significantly increased serum levels of ferritin and TSAT, hemoglobin levels were not consistently raised.
    American journal of health-system pharmacy: AJHP: official journal of the American Society of Health-System Pharmacists 07/2012; 69(14):1206-11. DOI:10.2146/ajhp110231 · 2.21 Impact Factor
  • Kristi W Kelley, Anne Marie Liles, Jessica A Starr
    American journal of health-system pharmacy: AJHP: official journal of the American Society of Health-System Pharmacists 04/2012; 69(7):563-5. DOI:10.2146/ajhp110425 · 2.21 Impact Factor
  • Anne Marie Liles
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    ABSTRACT: Because the kidney plays a large role in the absorption, distribution, metabolism, and elimination of drugs, significant medication-related problems can result from failure to properly adjust medications in patients with chronic kidney disease. It is the responsibility of all healthcare providers to be aware of necessary dose adjustments when reviewing medications, assessing drug therapy, changing drug therapy, or prescribing new medications.
    Nephrology nursing journal: journal of the American Nephrology Nurses' Association 01/2011; 38(3):263-70. · 0.77 Impact Factor
  • Jane S Davis, Anne Marie Liles, Debra J Hain
    Advance for nurse practitioners 07/2010; 18(7):30-2.
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    ABSTRACT: Objectives: Due to the increasing incidence of obesity and bariatric surgeries in the United States over the past several years, it is necessary for pharmacists to be knowledgeable in these areas. The purpose of this survey is to determine the extent to which obesity and post-bariatric surgery medication-related issues are covered in the curricula of Accreditation Council for Pharmacy Education (ACPE)-accredited schools/colleges of pharmacy, as this data is not available. Methods: A brief electronic survey was distributed via the following American College of Clinical Pharmacy (ACCP) Practice and Research Network (PRN) listservs: Education and Training, Ambulatory Care, Endocrine and Metabolism, GI/Liver/Nutrition. The goal participant sample was determined to be at least one survey response per ACPE-accredited institution (N=112). Results: Ninety respondents, from sixty ACPE-accredited institutions, have been catalogued. Institutions that currently incorporate obesity and post-bariatric surgery medication-related topics into required courses account for 41.9%. The majority of content is offered in the second and third professional years (40.5% and 52.4%, respectively), in lecture-based and some problem-based learning format (44.7% and 39.5%, respectively), is team-taught (61.9%) by pharmacy practice faculty (85.4%) with expertise in primary care (55%), and for less than 20% of the time devoted within a course. Other data has been collected about specific course content and will be reported. The majority of surveyed participants (51.8%) indicate that they do not believe their institution's current didactic approach coveres this content sufficiently. Conclusion: The minority of ACPE-accredited colleges/schools of pharmacy offer obesity and post-bariatric surgery medication-related content in their curricula. This shared information regarding where these educational components are covered in some ACPE-accredited curricula may encourage all institutions to incorporate or expand the coverage of this information.
    2010 American College of Clinical Pharmacy Spring Practice and Research Forum; 04/2010
  • Advances in Chronic Kidney Disease 03/2010; 17(2):207-207. DOI:10.1053/j.ackd.2010.01.011 · 1.94 Impact Factor
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    Anne Marie Liles, Kristi Kelley
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    ABSTRACT: Purpose: The purpose of this study was to determine the effectiveness of presentations provided by pharma- cists/pharmacy students in increasing medical residents' knowledge of treatment options and guidelines of vari- ous disease states. A secondary objective was to evaluate medical residents' satisfaction and perception of increased knowledge. Methods: A series of presentations were conducted by pharmacist/pharmacy students in an internal medicine res- ident clinic. Topics covered included dyslipidemia, hypertension (HTN), and asthma. Prior to each presentation, medical residents completed a pretest. One to 3 weeks after the presentations, residents were asked to complete a post-test identical to the pretests. At the conclusion of the series, medical residents responded to a follow-up sur- vey that assessed the residents' perception of the usefulness of the presentations and interest in future presenta- tions. Results: Twenty medical residents attended the dyslipidemia presentations and completed a pretest with 18 of these residents completing a post-test. The overall increase in median score was 7%. Twelve residents attended the HTN presentations and completed a pretest with 11 of these residents completing a post-test. The overall increase in median score was 17%. Thirteen residents attended the asthma presentations with 10 of these residents com- pleting a post-test. The overall increase in median score was 3%. Seventeen residents completed the follow-up sur- vey with "agree" being the most common response to all items indicating satisfaction and perception of increased knowledge. Conclusion: There was an overall improvement in pharmacotherapy knowledge of medical residents as antici- pated. Residents were satisfied with the presentations and perceived an increase in their pharmacotherapy knowl- edge.
    Hospital pharmacy 06/2008; 43(6):485-490. DOI:10.1310/hpj4306-485