Ichiro Tani

St. Marianna University School of Medicine, Yokohama-shi, Kanagawa-ken, Japan

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Publications (7)12.78 Total impact

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    ABSTRACT: LEARNING OBJECTIVES 1) To describe characteristic clinicopathological behavior of liver metastasis with rare variant of primary malignancy. 2) To review CT and MR imaging findings of metastatic liver tumor from rare primary malignancy. ABSTRACT Metastatic liver tumor is one of the most common nodular hepatic lesions. The majority of metastatic liver tumors are arised from primary carcinoma of colon, breast, lung, pancreas, and stomach. CT and MR imaging findings of these common metastatic lesions are usually non-specific, but metastatic liver tumors from uncommon primary site sometimes reveal unusual CT and MR imaging findings due to unique pathologies. This exhibit focuses on clinical manifestation, pathological and imaging features of rare metastatic liver tumors. We illustrate primitive neuroectodermal tumor (PNET), carcinoid, malignant lymphoma, laryngeal cancer, uterine cancer, leiomyosarcoma, liposarcoma, small intestinal cancer, melanoma, gastrointestinal stromal tumor, and melanoma.
    Radiological Society of North America 2005 Scientific Assembly and Annual Meeting; 11/2005

  • Journal of Nippon Medical School 11/2002; 69(5):471-5. DOI:10.1272/jnms.69.471 · 0.58 Impact Factor

  • American Journal of Roentgenology 06/2002; 178(5):1087-91. · 2.73 Impact Factor

  • American Journal of Roentgenology 05/2002; 178(5):1087-1091. DOI:10.2214/ajr.178.5.1781087 · 2.73 Impact Factor
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    ABSTRACT: Ultra slow infusion dynamic MR imaging using an infusion pump(IP-MRI) was performed in six patients with metastatic liver tumor or unresectable gastric cancer to evaluate ant-cancer drug distribution. We used un implanted port for the infusion of Gd-DTPA by infusion pump. On IP-MRI, the speed of Gd-DTPA infusion was very slow (0.01 ml/sec) , the same as drug infusion at chemotherapy. The contrast enhancement of tumors was extremely clear. Therefore, IP-MRI was considered feasible for the evaluation of drug distribution.
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica 05/2001; 61(5):246-8.
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    ABSTRACT: The purpose of this study was to evaluate the CT findings of rupture of hepatocellular carcinoma (HCC) in the caudate lobe of the liver. The CT scans of five cases of rupture of HCC in the caudate lobe of the liver were retrospectively reviewed and correlated with clinical records. All cases showed exophytic tumors in the caudate lobe of the liver and high-attenuation hematomas in the lesser sac on CT. A lesser sac hematoma may be a sentinel clot sign of rupture of HCC in the caudate lobe.
    European Radiology 01/2001; 11(3):422-426. DOI:10.1007/s003300000628 · 4.01 Impact Factor
  • T Kazama · Y Kurihara · I Tani · T Takahara · Y Nakajima · E Atari ·

    Journal of Computer Assisted Tomography 07/2000; 24(4):655-6. DOI:10.1097/00004728-200007000-00027 · 1.41 Impact Factor
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    American Journal of Roentgenology 05/2000; 174(4):965-71. DOI:10.2214/ajr.174.4.1740965 · 2.73 Impact Factor
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    ABSTRACT: Right lower abdominal pain is a common problem in the pediatric population. Ultrasonography (US) is a well-accepted imaging modality in the clinical management of this problem. One hundred and six consecutive pediatric patients with right lower abdominal pain were prospectively evaluated. There were 54 boys and 52 girls, with ages ranging from 3 to 15 years (mean: 9.9 years). Final diagnoses were established based on pathological findings or clinical follow-up. US had sensitivity of 90%, specificity of 98%, and accuracy of 94% in the diagnosis of acute appendicitis. Among all true negative cases (n = 55), there was a variety of US findings other than appendiceal abnormality in 21 cases including intestinal and/or mesenteric (n = 19), gallbladder (n = 1), and ovarian (n = 1) abnormalities. All 21 cases were managed medically without complication. We conclude that US of pediatric right lower abdominal pain is a reliable imaging modality not only for the diagnosis of surgical cases but for eliminating the unexpected surgical intervention.
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica 11/1995; 55(12):855-60.
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    ABSTRACT: Percutaneous transhepatic cholangioscopy (PTCS) is an useful technique to evaluate or treat biliary diseases, although PTCS is an invasive method for the patients. We used 5 F or 7 F of super fine cholangioscopy to treat two cases of choledocholithiasis after surgery without dilatation of drainage tract. We developed different types of bended sheath for supplement of lack of angle system in this cholangioscope. Furthermore, by using bended sheath, cholangioscopic view improved, because saline was injected at the same time via the sheath. We emphasize that super fine cholangioscope with bended sheath is a safe and useful modality for evaluation of biliary disease.
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica 07/1993; 53(6):719-21.
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    ABSTRACT: We retrospectively reviewed 53 CT scans in 42 patients with surgically proven intestinal injury following blunt abdominal trauma. Free air and localized low density fluid were specific signs of intestinal injury. Free peritoneal fluid without a known source, thickened bowel wall, and thickened mesentery were non-specific ones. Specific and non-specific findings were demonstrated in six (22%) and 23 (85%) of 27 CT scans performed within four hours following trauma, and 19 (73%) and 26 (100%) of 26 CT scans performed after four hours, respectively. CT is useful for the diagnosis of blunt intestinal injuries, but early diagnosis is difficult because of the lack of specific signs.
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica 01/1993; 52(12):1653-60.
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    ABSTRACT: The MR imaging and CT findings of corpus callosal injury were analyzed in 32 of 224 patients with acute head injuries. MR imaging was more sensitive than CT in the detection of callosal injuries. All 9 hemorrhagic lesions were visualized on both MR imaging and CT. Fifteen of 23 nonhemorrhagic lesions were not visualized on CT, although all nonhemorrhagic lesions were visualized on MR imaging. Twenty-four lesions of the corpus callosum were located in the splenium, but no lesion was located in the rostrum. Diffuse axonal shear injuries were visualized in 25 patients with callosal injury as associated traumatic lesions. Twenty-three patients with callosal injury had low initial Glasgow Coma Scale scores (less than 9), but 9 patients had high scores. Associated diffuse axonal shear injuries, especially in the brain stem could be a possible explanation for this difference. MR imaging is useful to detect traumatic lesions of the corpus callosum.
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica 08/1992; 52(7):949-59.
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    ABSTRACT: We compared the findings of noncontrast-enhanced CT with those of contrast-enhanced CT in 126 patients with blunt abdominal trauma to evaluate the usefulness of noncontrast-enhanced CT. In 112 of the patients, visceral injuries were confirmed by surgery or clinical follow-up including CT. Although noncontrast-enhanced CT diagnosed all patients with 12 intestinal injuries requiring immediate surgery, contrast-enhanced CT missed two of these patients because high density hematomas on noncontrast-enhanced CT became isodense after IV administration of contrast material. However, contrast-enhanced CT was superior to noncontrast-enhanced CT in the diagnosis of hepatic and renal injuries. A case of renal artery occlusion was only visualized on contrast-enhanced CT. We conclude that both noncontrast- and contrast-enhanced CT should be performed for the CT evaluation of blunt abdominal trauma.
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica 04/1992; 52(3):300-7.
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    ABSTRACT: Introduction Although the lungs have little solid component or protons, the organ has a lot of vessels and vascular networks which contains a large mount of pulmonary blood flow. Therefore, MR signal intensity of the lung should be mainly depend on the blood in the pulmonary vessels. However, pulmonary blood flow changes with cardiac beat, then the intensity of the blood in the pulmonary vessels should not be constant during the cardiac cycle. The purpose of this study is to demonstrate the signal difference of lung between diastolic phase and systolic phase and to introduce new perfusion weighted image of the lung without contrast material. Methods Five healthy subjects (three men and two women, 25-34 years old) without a history of chest disease volunteers to be examined under our new technique. All studies were performed using a 1.5-T VISART/EX MR system (Toshiba Corporation, Tokyo, Japan). Before acquisition of the 3D data set with respiratory gating, an EKG prep sequence was used for optimization of delay times for systolic and diastolic phases. Then, two fast imaging sequence were obtained by a one-shot 3D super fast spin-echo method with different ECG prep timings (systolic phase and diastolic phase). The imaging parameters were: TR/TE/TI, 2800-4100/80/190 ; NEX, 6; acquisition matrix, 256 x 256; FOV, 37-cm; and slice thickness, 5 mm. The scan time for each image was about 6 minutes. The 3D data set obtained during the systolic phase was used as a mask for subtraction from the 3D data obtained during the diastolic phase. In right lung, two ROIs were chosen: one within the ventral portion of the lung, and one corresponding region within the dorsal portion of the lung. The signal intensity of each ROI was measured and compared between diastolic images and systolic images. Results Both the ventral and dorsal ROIs in the diastolic phase had higher intensities than those in systolic phase (p=.041, p=.018, respectively). The dorsal ROIs had higher intensities than ventral ROIs in both diastolic and systolic phases (p=.039, p=.042, respectively). Discussion Our study revealed signal difference of the lung parenchyma between diastolic phase and systolic phase. One-shot 3D super fast spin-echo sequence in diastolic phase with respiratory gating could provide strong signal intensities from both pulmonary vessels and the lung parenchyma. The signal loss during systolic phase should result from fast flow through pulmonary vessels or flow void effect. Both diastolic and systolic phase scans showed higher signal intensity in the dorsal ROIs. The most possible cause for this dorsal-predominant intensity is difference in blood flow. A larger blood volume in regions with a gravity-dependent increase in perfusion could result in a strong intensity in the dorsal area. Subtraction image is very similar to MR pulmonary perfusion images using contrast materials. Subtraction process should suppress the intensity from the pulmonary interstitium and provide purely perfusion-weighted images without contrast materials. In conclusion, there is a significant difference of signal intensity of the lung parenchyma between diastolic phase and systolic phase. Subtraction process should provide a new perfusion weighted image of the lung without contrast material. One-shot 3D super fast spin-echo sequence with ECG and respiratory gating technique during diastolic phase reveals strong signals from both major vessels and pulmonary parenchyma. Same sequence in systolic phase shows decreased signal intensity of the lung. Subtraction image provides a perfusion weighted image of the lung without contrast material.

Publication Stats

55 Citations
12.78 Total Impact Points


  • 2000-2002
    • St. Marianna University School of Medicine
      • Department of Radiology
      Yokohama-shi, Kanagawa-ken, Japan
  • 2001
    • National Defense Medical College
      • Division of Radiology
      Tokorozawa, Saitama, Japan