Guang Liang Wang

Publications (4)0.69 Total impact

• Source

  Available from: PubMed Central

  Article: Ethyl 4-acetamido-3-acet-oxy-2-benzyl-3-methyl-butano-ate.

  Guang Liang Wang, Ji Mei Zhang, Xin Zhang, Hao Xu, Gui Yun Duan
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  ABSTRACT: The crystal structure of the title compound, C(18)H(25)NO(5), is stabilized by inter-molecular N-H⋯O hydrogen bonds, which form inversion dimers. The ethyl group is disordered over two positions in a 0.651 (12):0.349 (12) ratio.
  Acta Crystallographica Section E Structure Reports Online 12/2011; 67(Pt 12):o3418. · 0.35 Impact Factor
• Source

  Available from: Yanqing ge

  Article: Ethyl 1-(4-chloro-benz-yl)-3-(4-fluoro-phen-yl)-1H-pyrazole-5-carboxyl-ate.

  Yan Qing Ge, Ji Mei Zhang, Guang Liang Wang, Hao Xu, Bo Shi
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  ABSTRACT: In the title compound, C(19)H(16)ClFN(2)O(2), the pyrazole ring makes dihedral angles of 5.15 (6) and 77.72 (6)°, with the fluoro-phenyl and chloro-phenyl rings, respectively.
  Acta Crystallographica Section E Structure Reports Online 06/2011; 67(Pt 6):o1387. · 0.35 Impact Factor
• Article: [Investigation on the molecular mechanisms of anti-hepatocarcinoma herbs of traditional Chinese medicine by cell cycle microarray].

  Guang-Liang Wang, Cheng-Bin Chen, Jian-Ming Gao, Hong Ni, Tong-Shun Wang, Li Chen
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  ABSTRACT: To design DNA microarray and investigate the molecular anti-tumor mechanism of herbs of traditional Chinese medicine. cDNA microarrays consisting of 56 probes representing 24 human cell cycle genes were constructed, Four anti-hepatocarcinoma herbs including Radix Linderae, Hebra Artemisiae Annuae, Radix Amebiae, Radix Astragli, were chosen. Effects of herbs on SMMC-7721 cell cycle were observed by flow cytometry assay. Effects of herbs on cell cycle gene expression in SMMC-7721 cells were analyzed by comparing hybridization of Dig-Labeled cDNAs from herb-treated cells and cDNAs from untreated cells. Expressions of cell cycle geneswere changed in different degrees after herbs treated. Some genes were down-regulated and some genes were up-regulated. The changes in gene expression agreed with the results of flow cytometry assay. The results suggest that these herbs may have effects on cell cycle and DNA damage checkpoint genes which may be the mechanism of the herbs, and DNA microarray can be used to investigate the biological function of extracts of traditional Chinese medicine.
  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 02/2005; 30(1):50-4.
• Article: [Detection of differentially expressed genes in hepatocellularcarcinoma cells SMMC-7721 treated with Typhonium giganteum extract by mRNA differential display].

  Shun-qi Wang, Hong Ni, Hua Cheng, Guang-liang Wang, Tong-shun Wang, Li Chen
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  ABSTRACT: To screen and identify the differentially expressed genes in hepatocellular carcinoma cells SMMC-7721 responsing to the aqueous extract from dried powdered rhizomes of Typhonium giganteum (AEoTGE). The response of hepatocellular carcinoma cells SMMC-7721 to AEoTGE was explored with the technique of mRNA differential display. After hepatocarcinoma cells SMMC-7721 were treated by AEoTGE for 36 hours, 1 gene expression was upgrade and 1 gene expression was downgrade induced by AEoTGE. The research has provided important clues for the molecular mechanism of how hepatocarcinoma cells responseing to T. giganteum.
  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 11/2004; 29(10):974-7.