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ABSTRACT: Reconstruction of the anterior skull base is one of the greatest challenges for reconstructive surgeons. Sometimes, the defect is so large that a local flap is insufficient for the reconstruction. In this report, we present a case of malignant meningioma of the anterior skull base. The tumor was treated by surgical excision resulting in a large defect from the anterior skull base to the nasal cavity. The entire defect was within the cranial vault. The reconstruction was achieved using a free composite de-epithelialized anterolateral thigh and the vastus lateralis muscle flap. Postoperative monitoring included hand Doppler and daily endoscopic inspection. This patient was satisfied with the cosmetic result. After 10 months, magnetic resonance imaging (MRI), performed to assess the flap, demonstrated that the volume of the de-epithelialized skin paddle of the anterolateral thigh flap had not changed, and that there was no tissue atrophy between the patient's eyes that could have resulted in deformity.
Microsurgery 10/2011; 31(7):568-71. · 1.61 Impact Factor
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Advanced Materials 09/2011; 23(42):4933-7. · 13.88 Impact Factor
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Cheng-Han Hsieh,
Fang-Iy Wu,
Chun-Hsiang Fan,
Min-Jie Huang,
Kun-Yi Lu,
Pei-Yu Chou,
Yu-Han Ou Yang,
Shih-Hsiang Wu,
I-Chia Chen,
Shu-Hua Chou,
Ken-Tsung Wong,
Chien-Hong Cheng
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ABSTRACT: Five iridium bis(carbene) complexes, [Ir(pmi)(2)(pypz)] (1), [Ir(mpmi)(2)(pypz)] (2), [Ir(fpmi)(2)(pypz)] (3), [Ir(fpmi)(2)(pyim)] (4), and [Ir(fpmi)(2)(tfpypz)] (5) (pmi=1-phenyl-3-methylimdazolin-2-ylidene-C,C(2'); fpmi=1-(4-fluorophenyl)-3-methylimdazolin-2-ylidene-C,C(2'); mpmi=1-(4-methyl-phenyl)-3-methylimdazolin-2-ylidene-C,C(2'); pypz=2-(1H-pyrazol-5-yl)pyridinato; pyim=2-(1H-imidazol-2-yl)pyridinato; and tfpypz=2-(3-(trifluoromethyl)-1H-pyrazol-5-yl)pyridinato), were synthesized and their structures were characterized by NMR spectroscopy, mass spectroscopy and X-ray diffraction. These complexes showed phosphorescent emission with the emission maxima between 453 and 490 nm. Various spectrophotometric measurements, cyclic voltammetric studies, and density functional theory (DFT) calculations show that, unlike most of the phosphorescent cyclometalated iridium complexes, the lowest unoccupied molecular orbital (LUMO) energy and the emissive state of these iridium complexes are mainly controlled by the N,N'-heteroaromatic (N^N) ligand. Despite the fact that the LUMO levels of these complexes are mainly on the N^N ligands, the efficiencies of the electroluminescent (EL) devices are very high. For example, the EL devices using [Ir(mpmi)(2)(pypz)], [Ir(fpmi)(2)(pypz)], and [Ir(fpmi)(2)(tfpypz)] as the dopant emitters exhibited light- to deep-blue electrophosphorescence with external quantum efficiencies of 15.2, 14.1, and 7.6% and Commission Internationale d'Énclairage (x,y) coordinates (CIE(x,y)) of (0.14, 0.27), (0.14, 0.18) and (0.14, 0.10), respectively.
Chemistry 08/2011; 17(33):9180-7. · 5.93 Impact Factor
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ABSTRACT: Treatment of an avulsion or degloving injury of the hand is a difficult but not unusual operation for plastic reconstructive or hand surgeons. The avulsion may be salvaged by arteriovenous shunting technique. We present a patient with incomplete avulsion injury of the distal phalanx of thumb. Arteriovenous shunting was created and the wound reconstructed primarily under venous arterialization. The avulsed skin envelope was survived well and functional status was improved.
Microsurgery 09/2010; 30(6):469-71. · 1.61 Impact Factor
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Cheng-Han Hsieh
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ABSTRACT: Finger injuries are among the most common injuries treated in the emergency department. After surgical management, surgeons find that patients with finger injuries will sometimes experience severe tenderness when dressings are being changed. To reduce patients' discomfort an easy-to-use tool for painless finger wound dressing has been developed.
Surgery Today 02/2009; 39(5):456-8. · 1.22 Impact Factor
