-
[show abstract]
[hide abstract]
ABSTRACT: A 2 1/2-month-old female infant presented with multiple tense bullae on the hands and feet. Analysis of biopsy specimens confirmed our clinical impression of childhood bullous pemphigoid. Confirmatory data included type IV collagen mapping of the basement membrane zone, a readily available technique that helps distinguish childhood bullous pemphigoid from childhood epidermolysis bullosa acquisita. To our knowledge, our patient is the youngest described with childhood bullous pemphigoid, and we use this opportunity to review the literature and examine the clinical and immunologic features, treatment, and prognosis of this rare childhood immunobullous disorder.
Archives of Dermatology 04/1991; 127(3):378-86. · 3.89 Impact Factor
-
Archives of Dermatology 02/1991; 127(1):115, 118. · 3.89 Impact Factor
-
Archives of Dermatology 04/1989; 125(3):417, 420-1. · 3.89 Impact Factor
-
[show abstract]
[hide abstract]
ABSTRACT: We review the scientific literature regarding the aloe vera plant and its products. Aloe vera is known to contain several pharmacologically active ingredients, including a carboxypeptidase that inactivates bradykinin in vitro, salicylates, and a substance(s) that inhibits thromboxane formation in vivo. Scientific studies exist that support an antibacterial and antifungal effect for substance(s) in aloe vera. Studies and case reports provide support for the use of aloe vera in the treatment of radiation ulcers and stasis ulcers in man and burn and frostbite injuries in animals. The evidence for a potential beneficial effect associated with the use of aloe vera is sufficient to warrant the design and implementation of well-controlled clinical trials.
Journal of the American Academy of Dermatology 05/1988; 18(4 Pt 1):714-20. · 3.99 Impact Factor
