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ABSTRACT: Pubertal metrorrhagia is intermenstrual bleeding during the first two years following the menarche. Functional bleeding due to anovulation is the cause in 80% of cases, and most of the remaining cases are due to severe or mild bleeding disorders. Hormone therapy is indicated in every case. Severe bleeding with acute anemia can occur during the first cycles, requiring emergency estrogen and progestogen therapy. Estrogens are used alone in less severe forms. The treatment should be given for several cycles to protect from the risk of recurrence. Patients with severe, early pubertal metrorrhagia should receive follow-up for several years since they have a high risk of recurrent bleeding and persistent ovulation disorders.
Journal of Pediatric and Adolescent Gynecology 02/1996; 9(1):16-20. DOI:10.1016/S1083-3188(96)70005-0 · 1.68 Impact Factor