Olafemi Hermann Dave Brahi

University of Abomey-Calavi, Kotonu, Littoral, Benin

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Publications (3)3.59 Total impact

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    O H D Brahi · H Xiang · X Chen · S Farougou · X Zhao ·
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    ABSTRACT: Notable diversity observed within African ovine breeds makes them of great interests, but limited studies on genetic origins and domestications remain poorly understood. Here, we investigate the evolutionary status of West African native breeds, Djallonke and Sahelian sheep using mitogenome sequencing. Compared with other ovine mitogenome sequences, West African sheep were revealed a Eurasian origin, and the initially tamed sheep breeds in West Africa have been genetically mixed with each other and mixed with European breeds. Worldwide domestic sheep is deemed the Eurasian origin and migrated west to Europe and Africa and east to the Far East, in which dispersed and received selection for acclimation to autochthonic environment independently and ultimately evolved into different native breeds, respectively. Our results contribute to the comprehensive understanding of the domestic sheep origin and reveal multiple postdomestication genetic amelioration processes. © 2015 Blackwell Verlag GmbH.
    Journal of Animal Breeding and Genetics 04/2015; 132(5). DOI:10.1111/jbg.12144 · 1.57 Impact Factor
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    Hongxia Li · Olafemi Hermann Dave Brahi · Xingbo Zhao · Ningying Xu · Xiaofeng Zhao ·
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    ABSTRACT: Accumulated studies have documented extensive links between UCP3 polymorphisms and pig productive traits, and quantitative trait loci linkage results, on the other hand, provided extensive evidences showing that UCP3 was in the core of several QTLs for carcass and meat quality traits. In this research, we screened two substitutions in coding sequence and one 9-base continuous mutated site in 3'UTR of pig UCP3 gene using the reference population of 293 pigs which were F (2) generation of hybrids between Chinese native Jinhua pigs and European Pietrain. The two missense mutations of G1406A in Exon 3 and T3602C in Exon 5 which led to changes in the G150R and M259T, respectively, were digested by SmaI and introduced Tth111I separately for genotype analysis, and the 9-base continuous mutated site in the 3'UTR was analyzed by an AvaI cleavage. As a result, the 9-base continuous mutated site of 3'UTR manifested significantly close association with the backfat thickness at the sixth and seventh rib, but the polymorphisms of G1406A and T3602C were not associated significantly with any of the seven carcass traits. The same results were shown by RT-qPCR and western blotting. These findings inferred that UCP3 probably has tissue-specific effects on pig carcass traits.
    Molecular Biology Reports 06/2011; 39(2):1823-9. DOI:10.1007/s11033-011-0924-x · 2.02 Impact Factor
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Publication Stats

1 Citation
3.59 Total Impact Points


  • 2015
    • University of Abomey-Calavi
      • Laboratory of Research and Study in Applied Biology (LARBA)
      Kotonu, Littoral, Benin
  • 2011
    • China Agricultural University
      • State Key Laboratory for Agrobiotechnology
      Peping, Beijing, China