Mara Patricia Traina Chacon-Mikahil

Publications (3)5.79 Total impact

• Article: Comparison in responses to maximal eccentric exercise between elbow flexors and knee extensors of older adults.

  Felipe Romano Damas Nogueira, Cleiton Augusto Libardi, Kazunori Nosaka, Felipe Cassaro Vechin, Claudia Regina Cavaglieri, Mara Patricia Traina Chacon-Mikahil
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  ABSTRACT: OBJECTIVES: To compare the susceptibility of elbow flexors (EF) and knee extensors (KE) to eccentric exercise-induced muscle damage in older individuals, since ageing could modulate the difference in the susceptibility to muscle damage between muscles. DESIGN: Cross-sectional and cross-over study design. METHODS: Eight older (61.6±1.8 years) adults performed 5 sets of 6 maximal isokinetic (90°s(-1)) eccentric contractions of the EF (range of motion: 80-20°) and KE (30-90°) with the non-dominant limb in a randomised, counterbalanced order with 2 weeks between bouts. Maximal voluntary isometric (MVC-ISO) and concentric contraction torque, optimum angle, range of motion (ROM), muscle soreness and serum creatine kinase (CK) activity were measured before, immediately after (except CK), and 24, 48, 72 and 96h following exercise. Normalised changes in the variables following exercise were compared between EF and KE by a mixed model analysis of variance. RESULTS: Only MVC-ISO and ROM demonstrated significant group effects (p<0.05) for the comparison between EF and KE. Additionally, no significant group vs. time interactions (p>0.05) were found between EF and KE for any of the dependent variables changes. CONCLUSIONS: These results suggest that the KE of older adults are relatively as susceptible to muscle damage as their EF, or at the very least, the difference between EF and KE are small for older adults.
  Journal of science and medicine in sport / Sports Medicine Australia. 03/2013;
• Article: Comparison of maximal muscle strength of elbow flexors and knee extensors between younger and older men with the same level of daily activity.

  Felipe Romano Damas Nogueira, Cleiton Augusto Libardi, Felipe Cassaro Vechin, Manoel Emílio Lixandrão, Ricardo Paes de Barros Berton, Thiago Mattos Frota de Souza, Miguel Soares Conceição, Claudia Regina Cavaglieri, Mara Patricia Traina Chacon-Mikahil
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  ABSTRACT: Aging promotes neuromuscular loss, significantly reducing muscle strength. The magnitude of loss of strength seems to be different between the limbs, probably because of differences in activities of daily living (ADL). Therefore, the present study compared the muscle strength of the elbow flexors and knee extensors in younger (n = 7, mean age 23.3 ± 1.2 years) and older (n = 5, mean age 61.8 ± 2.6 years) men matched by ADL level. The study participants performed maximal concentric, isometric, and eccentric contractions of the elbow flexors and knee extensors using an isokinetic dynamometer following a crossover study design. Changes in the dependent variables were compared using mixed model analysis (limb versus age). The main results demonstrated that concentric, eccentric, and mean contraction torques for knee extensors were significantly (P < 0.05) higher for younger men than for elderly men. On the other hand, no statistically significant difference (P > 0.05) was found in concentric, isometric, eccentric, and mean torques for elbow flexors between younger and older individuals. These results show that elbow flexors maintain better strength than knee extensors through aging, even when comparing individuals with similar ADL levels.
  Clinical Interventions in Aging 01/2013; 8:401-7. · 2.08 Impact Factor
• Source

  Available from: Cleiton Augusto Libardi

  Article: Effect of resistance, endurance, and concurrent training on TNF-α, IL-6, and CRP.

  Cleiton Augusto Libardi, Giovana Vergínia De Souza, Claudia Regina Cavaglieri, Vera Aparecida Madruga, Mara Patrícia Traina Chacon-Mikahil
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  ABSTRACT: The aim of the present study was to evaluate the effects of 16 wk of resistance training (RT), endurance training (ET), and concurrent training (CT) on inflammatory markers, C-reactive protein (CRP), and functional capacity in sedentary middle-age men. Healthy subjects were randomized into RT (n = 11), ET (n = 12), CT (n = 11), and a control group (n = 13). The subjects performed three weekly sessions lasting about 60 min for 16 wk. Maximal strength was tested in bench press and leg press. The peak oxygen uptake (VO2peak) was measured in an incremental exercise test. Plasma tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and CRP levels were determined by an enzyme-linked immunosorbent assay. Maximal strength was increased after 16 wk, with no differences between RT and CT. VO2peak increased in ET and CT comparing before and after training. There were no significant differences in TNF-α, IL-6, and CRP comparing before and after training. Sixteen weeks of RT, ET, or CT in middle-age healthy men has not affected low and moderate IL-6, TNF-α, and CRP levels. CT performed in the same weekly frequency and session duration of ET and RT was effective in increasing both maximal strength and VO2peak, in addition to improvements in lipid profile.
  Medicine and science in sports and exercise 06/2011; 44(1):50-6. · 3.71 Impact Factor