Kyoko Tominaga

Tottori University, TTJ, Tottori, Japan

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Publications (2)2.63 Total impact

  • Source
    Masahisa Shindo · Yuichi Yoshida · Kyoko Tominaga · Osamu Yamamoto ·
    [Show abstract] [Hide abstract]
    ABSTRACT: Head and neck squamous cell carcinoma (SCC) rarely metastasizes to the skin. Metastases to the nasal tip from hypopharyngeal malignancies are extremely rare. We present a patient with nasal tip metastasis from hypopharyngeal SCC. A 74-year-old man with hypopharyngeal and esophageal carcinomas had a red nodule on his nasal tip (so-called "clown nose"). Histopathologically, atypical squamoid cell nests had proliferated in a lobular fashion from the dermis to subcutaneous tissue. Those atypical cells were identical to primary tumor cells in the hypopharynx. Based on these findings, a diagnosis of skin metastasis from hypopharyngeal SCC was made. In patients with malignant disease, biopsy should be performed for any suspicious skin lesion. In a patient like ours, "clown nose" might be a symptom of cutaneous metastasis. When clinicians note a "clown nose", they should consider malignancies in the neck and chest areas.
    Yonago acta medica 06/2013; 56(2):57-8. · 0.64 Impact Factor

  • European journal of dermatology: EJD 06/2011; 21(4):626-7. DOI:10.1684/ejd.2011.1387 · 1.99 Impact Factor

Publication Stats

1 Citation
2.63 Total Impact Points


  • 2011-2013
    • Tottori University
      • • Department of Medicine of Sensory and Motor Organs
      • • Faculty of Medicine
      TTJ, Tottori, Japan