Jun Hyeok Choi

Catholic University of Daegu, Hayang, North Gyeongsang, South Korea

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Publications (5)5.34 Total impact

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    ABSTRACT: Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant hereditary disorder characterized by the combined occurrence of tumors of the parathyroid gland, exocrine pancreas, and anterior pituitary gland. Calcitonin-secreting pancreatic endocrine tumors are rare, and calcitonin-secreting pancreatic endocrine tumors with MEN1 have not been reported in Korea. A 46-year-old woman was admitted for a right breast cancer operation. Abnormal blood chemistry findings were hypercalcemia and elevated calcitonin. The patient was diagnosed with a calcitonin-secreting pancreatic endocrine tumor, left thyroid papillary carcinoma, right breast invasive ductal carcinoma, a thymic carcinoid tumor, left adrenal adenoma, uterine myoma, and adenomyosis by computed tomography scan, and with pituitary macroadenoma by brain magnetic resonance imaging. We present this case with a review of the literature, because it is the first reported calcitonin-secreting pancreatic endocrine tumor with MEN 1 in Korea.
    01/2012; 83(6):817. DOI:10.3904/kjm.2012.83.6.817
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    ABSTRACT: Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare T-cell lymphoma characterized by involvement of the subcutaneous tissue of neoplastic T lymphocytes. SPTCL with hemophagocytic syndrome (HPS) is associated with an aggressive clinical course and treatment of SPTCL with HPS is not well established. Cyclophosphamide, doxorubicin, vincristine, prednisolone (CHOP) therapy is not successful in most patients suffering from SPTCL with HPS. The role of high dose chemotherapy followed by hematopoietic stem cell transplantation (HSCT) remains controversial. We report a case of relapsed SPTCL after CHOP chemotherapy and salvage chemotherapy followed by autologous HSCT, which had rapid improvement within weeks after cyclosporine and prednisolone. Immunosuppressive therapy may be an important and successful treatment option in SPTCL patients, even though they may have clinically aggressive disease.
    Cancer Research and Treatment 12/2011; 43(4):255-9. DOI:10.4143/crt.2011.43.4.255 · 3.32 Impact Factor
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    ABSTRACT: Diffuse large B cell lymphoma (DLBCL) of primary nodal (PN) or primary extranodal (PEN) origin may differ immunophenotypically, in that PEN lymphoma cells may originate from activated rather than germinal center B (GCB) cells. We evaluated the relationship between DLBCL clinicopathological features, including expression of B-cell differentiation markers, and primary tumor site. Expression of CD10, Bcl-6, Bcl-2, and MUM1 was determined in paraffin-embedded tissues from 123 patients with DLBCL. Of the 123 patients with DLBCL, 40 (32.5%) had the GCB and 83 (67.5%) had the non-GCB phenotype. Fifty-one patients (42%) showed disease involvement at PEN sites, including 29 with disease in the gastrointestinal (GI) tract (14 in the stomach, 15 in the intestine). Of these 51 patients, 16 (31.4%) were classified with the GCB and 35 (68.5%) with the non-GCB subtype. There were no differences in the frequencies of GCB and non-GCB subtypes among primary sites. Of the 72 patients with PN DLBCL, 22 (31%) had the GCB and 50 (69%) had the non-GCB subtype. There were no differences in the frequencies of GCB and non-GCB subtypes between patients with PN and PEN DLBCL. Although lactate dehydrogenase (LDH) concentration > normal, stage >II, and rituximab-cyclophosphamide, doxorubicin, vincristine, and prednisone (RCHOP) treatment were independent predictors of overall survival (OS), GCB subtype, and presence of PEN disease failed to predict survival upon multivariate analysis. There was no difference in GCB and non-GCB phenotypes between patients with PN and PEN DLBCLs. Additional studies are needed to further assess molecular differences between the two groups.
    Clinical lymphoma, myeloma & leukemia 06/2011; 11(5):403-8. DOI:10.1016/j.clml.2011.05.037 · 2.02 Impact Factor
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    Yong Kim · Seung Nam · Young Jin Cho · Jun Hyeok Choi ·
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    ABSTRACT: Objective: The aim of this study is to investigate the prevalence of musculoskeletal disorders of traditional Korean string instrument player playing the Gayageum, Geomungo, Ajaeng and Haegeum. Background: Many instrument players have suffered from the musculoskeletal pain of various body parts. However, there is no research on the prevalence of musculoskeletal disorders of traditional Korean string instrument players. Method: A questionnaire was developed to investigate pain symptoms of musculoskeletal problems through focus group interview. The questionnaire consisted of four parts: demographic factors, performance factors, pain symptoms and experience of musculoskeletal disorders. For the survey, 86 expert players participated. The data from the survey were analyzed by correlation analysis and chi-square analysis. Results: The symptoms of musculoskeletal disorders and severe pain were observed at neck, shoulder, back and knee. These problems were statistically related to the factor of height in Gayageum and Geomungo. In addition, the pain symptoms in Geomungo were analyzed according to age and career. Conclusion: The symptoms of playing-related musculoskeletal disorders of traditional Korean musical players were prevalently observed at neck, shoulder, back and knee. In addition, these symptoms were related to the various demographic factors such as age, body height, BMI, career, sex, hobby and stretching. Application: The results of this study can be used as the preliminary data for preventing the musculoskeletal injuries of traditional Korean musical instrument players.
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    Yong Kim · Ji Soo · Jun Hyeok Choi · Sang Eun Lee · Jiyoung Son ·
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    ABSTRACT: Objective: The aims of this study are to analyze psychological components through existing studies and categorize game components of immersive online game(MMORPG: massively multiplayer online role-playing game). Method: Many researchers reported that the flow of online game was positive behavior and could lead to addiction with immersive gamming through literature review. They analyzed MMORPG's flow components in the point of psychological view. We surveyed the causal factors of immersion and analyzed the flow components of online game point of game user's view. We extracted the flow components from MMORPG. Results: The re-categorization showed Motivation/Challenge, Operator, Feedback, Information, Design/Control and Interaction. Conclusion: In this study the psychological flow factors are re-categorized by game user's view for the basis of quantitative analysis.

Publication Stats

6 Citations
5.34 Total Impact Points


  • 2011
    • Catholic University of Daegu
      • Department of Internal Medicine
      Hayang, North Gyeongsang, South Korea
    • Catholic University of Korea
      Sŏul, Seoul, South Korea