Ignacio Periñán Domínguez

Publications (1)5.86 Total impact

• Article: Asymmetric synthesis of chiral δ-lactones containing multiple contiguous stereocenters.

  Jennifer Peed, Ignacio Periñán Domínguez, Iwan R Davies, Matt Cheeseman, James E Taylor, Gabriele Kociok-Köhn, Steven D Bull
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  ABSTRACT: A versatile methodology for the asymmetric synthesis of chiral δ-lactones containing multiple contiguous stereocenters has been developed that relies on a series of Evans' aldol, hydroxyl-directed cyclopropanation, methanolysis, and Hg(II) mediated cyclopropane ring-opening reactions for stereocontrol.
  Organic Letters 06/2011; 13(14):3592-5. · 5.86 Impact Factor