Brennan D Haase

Publications (2)12.21 Total impact

• Article: Reduced Emotion Processing Efficiency in Healthy Males Relative to Females.

  Sara L Weisenbach, Lisa J Rapport, Emily M Briceno, Brennan D Haase, Aaron C Vederman, Linas A Bieliauskas, Robert C Welsh, Monica N Starkman, Melvin G McInnis, Jon-Kar Zubieta, Scott A Langenecker
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  ABSTRACT: This study examined sex differences in categorization of facial emotions and in activation of brain regionssupportive of those classifications. In Experiment 1, performance on the Facial Emotion Perception Test (FEPT) was examined among 75 healthy females and 63 healthy males. Females were more accurate in the categorization of fearful expressions relative to males. In Experiment 2, 3T fMRI data were acquired for a separate sample of 21 healthy females and 17 healthy males while performing the FEPT. Activation to neutral facial expressions was subtracted from activation to sad, angry, fearful, and happy facial expressions, respectively. Althoughfemales and males demonstrated activation in some overlapping regions for all emotions, many regions were exclusive to females or to males. For anger,sad, and happy, males displayed a larger extent of activation than did females, and greater height of activation was detected in diffuse cortical and subcorticalregions. For fear, males displayed greater activation than females only in right postcentral gyri. With one exception in females, performance was not associated with activation. Results suggest that females and males process emotions using different neural pathways, and these differences cannot be explained by performance variations.
  Social Cognitive and Affective Neuroscience 11/2012; · 6.13 Impact Factor
• Article: Modality-specific alterations in the perception of emotional stimuli in Bipolar Disorder compared to Healthy Controls and Major Depressive Disorder.

  Aaron C Vederman, Sara L Weisenbach, Lisa J Rapport, Hadia M Leon, Brennan D Haase, Lindsay M Franti, Michael-Paul Schallmo, Erika F H Saunders, Masoud M Kamali, Jon-Kar Zubieta, Scott A Langenecker, Melvin G McInnis
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  ABSTRACT: Affect identification accuracy paradigms have increasingly been utilized to understand psychiatric illness including Bipolar Disorder (BD) and Major Depressive Disorder (MDD). This investigation focused on perceptual accuracy in affect identification in both visual and auditory domains among patients with BD, relative to Healthy Controls (HC) and patients with MDD. Demographic and clinical variables, in addition to medications were also investigated. The visual Facial Emotion Perception Test (FEPT) and auditory Emotional Perception Test (EPT) were administered to adults with BD (n=119) and MDD (n=78) as well as HC (n=66). Performance on the FEPT was significantly stronger than on the EPT irrespective of group. Performance on the EPT did not significantly differentiate the groups. On the FEPT, BD samples had the greatest difficulty relative to HC in identification of sad and fearful faces. BD participants also had greater difficulty identifying sad faces relative to MDD participants though not after controlling for severity of illness factors. For the BD (but not MDD) sample several clinical variables were also correlated with FEPT performance. The findings suggest that disruptions in identification of negative emotions such as sadness and fear may be a characteristic trait of BD. However, this effect may be moderated by greater illness severity found in our BD sample.
  Cortex 05/2011; 48(8):1027-34. · 6.08 Impact Factor