Nilüfer Onak Kandemır

Publications (3)1.42 Total impact

• Article: Primary intestinal diffuse large B-cell lymphoma forming multiple lymphomatous polyposis.

  Figen Barut, Nilüfer Onak Kandemır, Kemal Karakaya, Neslihan Kökten, Sükru Oğuz Ozdamar
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  ABSTRACT: Multifocal and skip involvement is quite a rare developmental pattern for primary gastrointestinal lymphomas. A 25-year-old male patient with diffuse large B-cell lymphoma of the small intestine, with macroscopic features and clinical aspects imitating Crohn's disease and attracting attention with cobblestone-like appearance, is presented herein together with the clinical and pathological features.Multiple ulcerated lesions were also observed infiltrating the serosa with polypoid appearance, 2.5 cm in largest diameter, within the resected jejunoileal specimen, which displayed patchy, healthy-appearing mucosal areas. In microscopic examination, a tumoral infiltration was observed comprised of pleomorphic, atypical lymphoid cells with abundant eosinophilic cytoplasm, marked nucleoli and vesicular nuclei. A B-cell phenotype immunoreaction was observed by vimentin, LCA, CD20, and CD79a in those atypical cells. The diagnosis of the case was diffuse large B-cell lymphoma.The possibility of the presence of this disorder, although rare, is emphasized here for patients applying to the hospital with the signs and symptoms of Crohn's disease.
  The Turkish journal of gastroenterology: the official journal of Turkish Society of Gastroenterology 06/2011; 22(3):324-8. · 0.47 Impact Factor
• Article: Multiorgan involvement in HHV-8-positive multifocal inflammatory myofibroblastic tumor.

  Nilüfer Onak Kandemır, Banu Doğan Gün, Oktay İrkörücü, Hüsnu Tokgöz, Figen Barut, Mustafa Cömert, Şükru Oğuz Özdamar
  The Turkish journal of gastroenterology: the official journal of Turkish Society of Gastroenterology 04/2011; 22(2):235-6. · 0.47 Impact Factor
• Article: Malignant melanoma associated with congenital melanocytic nevus and diagnosed with intestinal metastases: Two case reports.

  Nilüfer Onak Kandemır, Burak Bahadir, Sibel Bektaş, Figen Barut, Gamze Yurdakan, Banu Doğan Gün, Hüseyin Engın, Selim Aydemır, Sükru Oğuz Ozdamar
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  ABSTRACT: Congenital melanocytic nevi are hamartomatous lesions that develop from the neural crest and arise during odontogenesis. In this report, we present two malignant melanoma cases developed from congenital melanocytic nevi and revealed by gastrointestinal system metastases. The first case was a 71-year-old female who presented with pleural and peritoneal effusion and underwent biopsy due to detection of nodular lesions in the duodenum by endoscopic examination. The second case was a 36-year-old male patient who presented with abdominal pain in whom segmental ileal resection was performed due to mass lesions causing invaginations in the ileum. Histopathological examination of the lesions showed a diffuse neoplastic infiltration comprising the entire mucosal layers. In neoplastic cells having a marked atypia and pleomorphism, immunoreactions with S-100, HMB-45, and Melan A were detected. Both cases were diagnosed as malignant melanoma. Abdominal skin in the first case and the femoral region in the second case exhibited congenital melanocytic nevi, and those lesions were determined to show a transformation towards malignant melanoma in the histopathological studies. Malignant melanoma development in gastrointestinal system may have a primary or metastatic character. Definitive diagnosis always requires detailed clinical, histopathological and immunohistochemical analyses.
  The Turkish journal of gastroenterology: the official journal of Turkish Society of Gastroenterology 02/2011; 22(1):77-82. · 0.47 Impact Factor