Nicolau Conte Neto

Publications of Nicolau Conte Neto

• Calvarial autogenous bone graft for maxillary ridge and sinus reconstruction for rehabilitation with dental implants.

  Authors: Alliny Souza Bastos, Rubens Spin-Neto, Nicolau Conte Neto, Keidy Gallina, Rodolfo Jorge Boeck-Neto, Cláudio Marcantonio, Elcio Marcantonio, Elcio Marcantonio Júnior

  The Journal of oral implantology. 04/2012;

  Abstract Autogenous bone grafting is the gold-standard technique for bone augmentation procedures prior to implants placement. If the amount of available intraoral donor bone is insufficient, it isAbstract Autogenous bone grafting is the gold-standard technique for bone augmentation procedures prior to implants placement. If the amount of available intraoral donor bone is insufficient, it is necessary to harvest bone graft from extra-oral sites, such as calvaria. Although this technique is well established, only a few case reports show the histological analysis of the grafted bone at the moment of implants placement. This present paper reports a case of a 48 year-old female patient, with a critical atrophic maxillary ridge reconstructed using autogenous calvarial bone graft prior to implants placement, with clinical and histological evaluation. Bone was collected under general anesthesia, from the parietal bone. The outer cortical originated the bone blocks, and the medullar bone layer between was collected to be used in the sinus augmentation procedure, together with five of the bone blocks triturated. Six months after bone augmentation, eight implants were placed in the grafted area, and two biopsies were retrieved (anterior and the posterior regions), allowing the visualization of the bone remodeling process in the grafted areas. The patient had a stable recovery. Our results showed that although necrotic bone could still be seen in the outer layer of the grafted area, the interface between this necrotic bone and the already remodeled bone was consistent with biocompatibility. Two-year radiographic evaluation showed success of the grafts and the implants in supporting an esthetic and functionally stable prosthesis. Summarizing, calvarial bone grafts are a viable alternative for the attainment of adequate bone volume prior to implants placement.

• Epidemiological aspects of rheumatoid arthritis patients affected by oral bisphosphonate-related osteonecrosis of the jaws.

  Authors: Nicolau Conte-Neto, Alliny Souza Bastos, Rosemary Adriana Chierici Marcantonio, Elcio Marcantonio Junior

  Head & face medicine. 03/2012; 8:5.

  ABSTRACT: This literature review aims to evaluate the epidemiologic profile of patients with rheumatoid arthritis (RA) that developed a bisphosphonate-related osteonecrosis that affect the jawsABSTRACT: This literature review aims to evaluate the epidemiologic profile of patients with rheumatoid arthritis (RA) that developed a bisphosphonate-related osteonecrosis that affect the jaws (BRONJ), including demographic aspects, as well as clinical and therapeutic issues. A search of PUBMED/MEDLINE, Scopus, and Cochrane databases from January 2003 to September 2011 was conducted with the objective of identifying publications that contained case reports regarding oral BRONJ in RA patients. Patients with RA who develop oral BRONJ are usually women above 60 years taking steroids and long-term alendronate. Most of them have osteoporosis, and lesions, triggered by dental procedures, are usually detected at stage II in the mandible. Although there is no accepted treatment protocol, these patients seem to have better outcomes with conservative approaches that include antibiotic therapy, chlorhexidine, and drug discontinuation.

• Is rheumatoid arthritis a risk factor for oral bisphosphonate-induced osteonecrosis of the jaws?

  Authors: Nicolau Conte Neto, Alliny de Souza Bastos, Rosemary Adriana Chierici-Marcantonio, Elcio Marcantonio

  Medical hypotheses. 08/2011; 77(5):905-11.

  Bisphosphonate-related osteonecrosis of the jaws is a relevant side-effect of these drugs that has been generating a great concern through increasing reports, worldwide, of this bone necrosis. AmongBisphosphonate-related osteonecrosis of the jaws is a relevant side-effect of these drugs that has been generating a great concern through increasing reports, worldwide, of this bone necrosis. Among several BRONJ hypothetical co-factors that could play a role in BRONJ pathogenesis, rheumatoid arthritis (RA) has been included as a relevant risk factor for BRONJ; however, until now the relationship between these diseases has not been fully explained. Thus, the purpose of this paper is to establish hypothetical factors that could link these two diseases, considering mainly inflammatory components and the organism effects of medicines used to treat RA, particularly steroids and methotrexate (MTX).

• Oral bisphosphonate-related osteonecrosis of the jaws in rheumatoid arthritis patients: a critical discussion and two case reports.

  Authors: Nicolau Conte-Neto, Alliny S Bastos, Luis C Spolidorio, Rosemary Ac Marcantonio, Elcio Marcantonio

  Head & face medicine. 01/2011; 7:7.

  Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a clinical condition characterized by the presence of exposed bone in the maxillofacial region. Its pathogenesis is still undetermined, butBisphosphonate-related osteonecrosis of the jaw (BRONJ) is a clinical condition characterized by the presence of exposed bone in the maxillofacial region. Its pathogenesis is still undetermined, but may be associated with risk factors such as rheumatoid arthritis (RA). The aim of this paper is to report two unpublished cases of BRONJ in patients with RA and to conduct a literature review of similar clinical cases with a view to describe the main issues concerning these patients, including demographic characteristics and therapeutic approaches applied. Two case reports of BRONJ involving RA patients were discussed Both patients were aging female taking alendronate for more than 3 years. Lesions were detected in stage II in posterior mandible with no clear trigger agent. The treatment applied consisted of antibiotics, oral rinses with chlorhexidine, drug discontinuation and surgical procedures. Complete healing of the lesions was achieved. This paper brings to light the necessity for rheumatologists to be aware of the potential risk to their patients of developing BRONJ and to work together with dentists for the prevention and early detection of the lesions. Although some features seem to link RA with oral BRONJ and act as synergistic effects, more studies should be developed to support the scientific bases for this hypothesis.

• Lip cavernous hemangioma in a young child.

  Authors: Erica Dorigatti de Avila, Rafael Scaf de Molon, Nicolau Conte Neto, Marisa Aparecida Cabrini Gabrielli, Eduardo Hochuli-Vieira

  Brazilian dental journal. 01/2010; 21(4):370-4.

  Hemangiomas are benign tumors of infancy and childhood, characterized by a phase of fast growth with endothelial cell proliferation, occurring in 10-12% of children at 1 year of age. It is known thatHemangiomas are benign tumors of infancy and childhood, characterized by a phase of fast growth with endothelial cell proliferation, occurring in 10-12% of children at 1 year of age. It is known that hemangiomas of infancy are most commonly located on the head and neck region (around 60% of cases) and occur more frequently in the lips, tongue, and palate. Approximately 50% of hemangiomas have complete resolution, and 90% of them are resolved up to the age of 9. Complications occur in only 20% of the cases, the most common problem being ulceration with or without infection. The treatment depends on lesion location, size and evolution stage, and the patient's age. Surgery is usually indicated when there is no response to systemic treatments, or even for esthetic reasons, being performed as a simple excision in combination or not with plastic surgery. This paper reports a case of lip cavernous hemangioma in a 4-year-old child, who was submitted to 3 sessions of vascular sclerosis due to the size of the lesion, before undergoing simple excision of the hemangioma. Two years of postoperative clinical follow-up shows treatment success with no recurrence of the lesion.

• Oral manifestations of vitamin B12 deficiency: a case report.

  Authors: Hélder Antônio Rebelo Pontes, Nicolau Conte Neto, Karen Bechara Ferreira, Felipe Paiva Fonseca, Gizelle Monteiro Vallinoto, Flávia Sirotheau Corrêa Pontes, Décio Dos Santos Pinto

  Journal (Canadian Dental Association). 10/2009; 75(7):533-7.

  Megaloblastic anemias are a subgroup of macrocytic anemias, in which distinctive morphologic abnormalities occur in red cell precursors in bone marrow, namely megaloblastic erythropoiesis. Of theMegaloblastic anemias are a subgroup of macrocytic anemias, in which distinctive morphologic abnormalities occur in red cell precursors in bone marrow, namely megaloblastic erythropoiesis. Of the many causes of megaloblastic anemia, the most common are disorders resulting from cobalamin or folate deficiency. The clinical symptoms are weakness, fatigue, shortness of breath and neurologic abnormalities. The presence of oral signs and symptoms, including glossitis, angular cheilitis, recurrent oral ulcer, oral candidiasis, diffuse erythematous mucositis and pale oral mucosa offer the dentist an opportunity to participate in the diagnosis of this condition. Early diagnosis is important to prevent neurologic signs, which could be irreversible. The aim of this paper is to describe the oral changes in a patient with megaloblastic anemia caused by a dietary deficiency of cobalamin.