J Borah

Publications (3)7.17 Total impact

• Article: Epidemiological concordance of Japanese encephalitis virus infection among mosquito vectors, amplifying hosts and humans in India.

  J Borah, P Dutta, S A Khan, J Mahanta
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  ABSTRACT: SUMMARYA temporal relationship of Japanese encephalitis virus (JEV) transmission in pigs, mosquitoes and humans revealed that sentinel pig seroconversions were significantly associated with human cases 4 weeks before (P=0·04) their occurrence, highly correlated during the same time and 2 weeks before case occurrence (P<0·001), and remained significantly correlated up to 2 weeks after human case occurrence (P<0·01). JEV was detected in the same month in pigs and mosquitoes, and peaks of pig seroconversion were preceded by 1-2 months of peaks of infection in vectors. Kaplan-Meier analysis indicated that detection of JEV-positive mosquitoes was significantly associated with the median time to occurrence of seroconversion in pigs (P<0·05). This study will not only help in predicting JEV activity but also accelerate timely vector control measures and vaccination programmes for pigs and humans to reduce the Japanese encephalitis risk in endemic areas.
  Epidemiology and Infection 02/2012; · 2.84 Impact Factor
• Article: First evidence of chikungunya virus infection in Assam, Northeast India.

  P Dutta, S A Khan, A M Khan, J Borah, P Chowdhury, J Mahanta
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  ABSTRACT: During June-September 2008, an illness characterized by fever, headache and joint pain was reported in Assam state, northeast India. It presented characteristic features resembling chikungunya or dengue virus infection based on clinical symptoms. Dengue and chikungunya IgM antibody was detected in 10.0% (28/280) and 3.6% (10/280) patients respectively. The chikungunya positive patients did not travel to and from any endemic region confirming indigenous transmission. Persistent arthralgia and hearing loss has been observed in a recovered patient. Entomological surveys revealed the presence of vectors viz. Aedes aegypti and Aedes albopictus. This is the maiden report of chikungunya occurrence in Northeast India.
  Transactions of the Royal Society of Tropical Medicine and Hygiene 06/2011; 105(6):355-7. · 2.16 Impact Factor
• Article: Malaria control in a forest fringe area of Assam, India: a pilot study.

  P Dutta, A M Khan, S A Khan, J Borah, C K Sharma, J Mahanta
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  ABSTRACT: A study was conducted to evaluate the preventive efficacy of insecticide-treated mosquito nets (ITMNs) and mosquito repellent (MR) in a malaria-endemic foothill area of Assam, India, with forest ecosystem. During the first year, a survey was conducted in four demarcated sectors (A-D) to observe the malaria endemicity and vector prevalence patterns before implementing intervention measures. All four sectors were endemic for malaria. The prevalence of established malaria vectors such as Anopheles dirus, A. minimus and A. philippinensis was observed. During the second year, intervention measures were implemented in the four sectors as follows: A, ITMN + MR; B, ITMN; C, MR; D, no intervention. The most effective intervention was in sector A, followed by sectors B and C. Sectors A and B exhibited significantly higher (P < 0.001) malaria protective efficacy during both the first and second years of intervention compared with sector D. The total vector population in the three intervention sectors decreased significantly compared with that of the non-intervention one. Information-education-communication activities motivated the residents to participate actively in the intervention programme. The finding could be an effective model for containment of high malaria morbidity in inaccessible forest fringe areas of the northeastern region of India.
  Transactions of the Royal Society of Tropical Medicine and Hygiene 06/2011; 105(6):327-32. · 2.16 Impact Factor