Publications (2)0 Total impact
Article: [Allergens and their relationships to childhood bronchial asthma in the Jiading District of Shanghai].[show abstract] [hide abstract]
ABSTRACT: To study allergens and their relationship to the occurrence of childhood bronchial asthma in the Jiading District of Shanghai. Three hundred and eighty-two 4 to 12-year-old children with asthma in the remission stage from Nanxiang Hospital in the Jiading District of Shanghai were used as a case group (asthma group), and 402 children from two primary schools and two kindergartens in Jiading were enrolled by cluster sampling and served as control group. Parents of the children completed a questionnaire on living conditions and allergy-related disease history. Skin prick test (SPT) for 18 common allergens was carried out in both groups. In order to examine the effect of environment and living conditions on SPT results, children in the control group were further divided into two sub-groups according to birth place: migrant (219 cases) and resident (183 cases). SPT results revealed that the main allergens identified in the Jiading region were dermatophagoides farinae, house dust mites, shrimps, cockroaches, and dog hair. The SPT positive rate was 67.9% in the asthma group, and this was significantly higher than in the control group (31.8%) (P<0.01). The environment and living conditions in the migrant group were significantly different from the resident group (P<0.01), whereas the SPT positive rate for this group was significantly lower than in the resident group (P<0.01). Allergens in the Jiading region mainly originate from dermatophagoides farinae, household dust mites, shrimps, cockroaches and dog hair. Children with asthma are more susceptible to allergens. Environment and living conditions may be relevant, to a certain extent, to an SPT positive rate.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 07/2012; 14(7):521-3.
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ABSTRACT: To study the clinical characteristics of human bocavirus (HBoV) infection in children. Nasal and throat swab samples were collected in 843 children with lower respiratory tract infection. The multiple RT-PCR method was used to detect HBoV and six other common respiratory tract viruses. The clinical characteristics of HboV positive cases were investigated. Among 843 cases, 90 were HboV positive (10.7%), 131 were respiratory syncytial virus (RSV) positive (15.5%), 117 were influenza virus positive (13.9%), 84 were parainfluenza virus positive (10.0%), 55 were rhinovirus positive (6.5%), 48 were coronavirus positive (5.7%), and 33 were human metapneumovirus positive (3.7%). Of the 90 HBoV infected patients, 45 (50%) showed a co-infection with other respiratory tract viruses. Among them, 33 were infected with one other type of virus (37%), 11 (12%) were infected with two other types of virus, and 1 case (1%) was infected with other three viruses. The HBoV positive rate in children with wheezing was significantly higher than those without wheezing (17.0% vs 9.2%; P<0.01). The common clinical manifestations of HBoV-infected patients included frequent coughing, wheezing and fever. There were no significant differences in the frequency of wheezing between HBoV and RSV infected patients. HBoV positive rate detected from children with wheezing is higher than from children without wheezing, suggesting that apart from RSV, HBoV is another virus causing wheezing in children with respiratory tract infection. Co-infections of HBoV with other respiratory track viruses can be present in some patients.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 04/2011; 13(4):300-2.