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ABSTRACT: Primary or tropical pyomyositis is a subacute infection of the skeletal muscle complicated by abscess formation. The disease is rare in the temperate climates and often misdiagnosed because of the vague clinical presentation. We herein report a case of a 38-year-old diabetic patient with a history of recent bone marrow biopsy presented multifocal primary pyomyositis complicated by meningitis.Il Giornale di chirurgia 04/2011; 32(4):185-7.