A. Bergeret

Hospices Civils de Lyon, Lyons, Rhône-Alpes, France

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Publications (78)104.68 Total impact

  • [Show abstract] [Hide abstract]
    ABSTRACT: The aim of this work was to review the available literature on occupational risk factors associated with ovarian cancer. A PubMed search was performed using an algorithm with the following search terms: ovary, ovarian, exposure, work, occupation. Relevant articles were selected through assessment of titles and abstracts as well as through the reference lists of related articles. A total of 54 studies were selected for this review, including 17 studies on asbestos exposure and risk of ovarian cancer and, 16 studies on other occupational factors (5 cohort studies and 11 case control studies). An increased risk of ovarian cancer has been reported for several occupations (teachers, administration employees, nurses, religious workers) and various industrial sectors (biomedical research, telephony industry, hairdresser and beautician, printing factories) with inconsistent results. Moreover, in many of these studies, individual risk factors of ovarian cancers were not considered. Despite methodological limitations of published studies, a significantly increased risk for ovarian cancer associated with asbestos exposure have been consistently reported.
    Bulletin du cancer 12/2014; 101(12):1089-1108. DOI:10.1684/bdc.2014.1978 · 0.64 Impact Factor
  • Archives des Maladies Professionnelles et de l Environnement 06/2014; 75(3):S19. DOI:10.1016/j.admp.2014.03.062 · 0.09 Impact Factor
  • Archives des Maladies Professionnelles et de l Environnement 06/2014; 75(3):S1. DOI:10.1016/j.admp.2014.03.004 · 0.09 Impact Factor
  • Archives des Maladies Professionnelles et de l Environnement 06/2014; 75(3):S1. DOI:10.1016/j.admp.2014.03.005 · 0.09 Impact Factor
  • Archives des Maladies Professionnelles et de l Environnement 06/2014; 75(3):321. DOI:10.1016/j.admp.2014.03.194 · 0.09 Impact Factor
  • T. Lassiege, E. Fort, A. Bergeret
    Archives des Maladies Professionnelles et de l Environnement 11/2013; 74(5):556. DOI:10.1016/j.admp.2013.07.112 · 0.09 Impact Factor
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    ABSTRACT: Objectives: A case-control study was carried out to identify driving behaviors associated with the risk of on-duty road accident and to compare driving behaviors according to the type of journey (on duty, commuting, and private) for on-duty road accident victims. Methods: Cases were recruited from the Rhône Road Trauma Registry between January 2004 and October 2005 and were on duty at the time of the accident. Control subjects were recruited from the electoral rolls of the case subjects' constituencies of residence. Cases' and controls' driving behavior data were collected by self-administered questionnaire. A logistic regression was performed to identify behavioral risk factors for on-duty road accidents, taking into account age, sex, place of residence, road accident risk exposure, socio-occupational category, and type of road user. A second analysis focused specifically on the case subjects, comparing their self-assessed usual behaviors according to the type of journey. Results: Significant factors for multivariate analysis of on-duty road accidents were female gender, history of on-duty road accidents during the previous 10 years, severe time pressure at work, and driving a vehicle not belonging to the driver. On-duty road accident victims reported behavioral risk factors more frequently in relation to driving for work than driving for private reasons or commuting: nonsystematic seat belt use, cell phone use at least once daily while driving, and history of accidents with injury during the previous 10 years. Conclusions: This study provides knowledge on behavioral risk factors for on-duty road accidents and differences in behavior according to the type of journey for subjects who have been on-duty road accident victims. These results will be useful for the design of on-duty road risk prevention.
    Traffic Injury Prevention 03/2013; 14(4):353-9. DOI:10.1080/15389588.2012.719091 · 1.29 Impact Factor
  • 01/2013; 8(1):1-12. DOI:10.1016/S1877-7856(12)29980-5
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    ABSTRACT: OBJECTIVES: Trichloroethylene (TCE) is suspected of association with elevated risk of cervical cancer. A case-control study was performed in a geographical area in which occupational TCE exposure is high. The study objective was to analyze the correlation between occupational TCE exposure and cervical cancer (including precancerous conditions). METHODS: Case and control subjects were recruited by gynecologists. General and occupational data were collected by telephonic interviews. An industrial hygienist assessed occupational TCE exposure on a task-exposure matrix. Analysis focused on occupational TCE exposure at various levels and on cumulative dose. Multivariate analysis was performed to take account of the various risk factors. RESULTS: In total, 67 case and 67 age-matched control subjects were included. Mean age was 36 years in both groups. Five of the possible general risk factors correlated significantly with cervical dysplasia or cancer: number of partners, history of genital or anal wart, interval between first period and first sexual relation, parity, and body mass index, the last three showing inverse correlation. Elevated risk was found in women who had had jobs as manual workers according to the PCS French classification (professions and socioprofessional categories), and production and related workers according to ISCO classification (International Standard Classification of Occupations), with odds ratios (ORs), adjusted on general and medical risk factors, of 7.68 [95% confidence interval (CI): 1.39-42.54] and 7.48 (1.30-43.24), respectively, among skilled service sector workers; the adjusted OR was close to significance, at 4.67 (95% CI: 0.92-23.67). No occupational sectors were significantly associated with elevated risk. In all, 17 (25.4%) case and 15 (22.4%) control subjects were exposed to TCE: raw OR = 1.17 (95% CI: 0.54-2.52), adjusted OR = 1.51 (95% CI: 0.42-5.41). There was no significant correlation between cumulative dose and exposure time. CONCLUSIONS: The study found no significantly increased risk of cervical dysplasia or cancer associated with occupational TCE exposure.
    Annals of Occupational Hygiene 10/2012; 57(3). DOI:10.1093/annhyg/mes075 · 2.07 Impact Factor
  • M.A. Denis, R. Cadot, A. Bergeret
    Archives des Maladies Professionnelles et de l Environnement 06/2012; 73(3):459-460. DOI:10.1016/j.admp.2012.03.430 · 0.09 Impact Factor
  • Archives des Maladies Professionnelles et de l Environnement 06/2012; 73(3):438. DOI:10.1016/j.admp.2012.03.418 · 0.09 Impact Factor
  • Archives des Maladies Professionnelles et de l Environnement 06/2012; 73(3):570. DOI:10.1016/j.admp.2012.03.659 · 0.09 Impact Factor
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    ABSTRACT: Knowledge on the time-course (trends) of work-related asthma (WRA) remains sparse. The aim of this study was to describe WRA trends in terms of industrial activities and the main causal agents in France over the period 2001-2009. Data were collected from the French national network of occupational health surveillance and prevention (Réseau National de Vigilance et de Prévention des Pathologies Professionnelles (RNV3P)). Several statistical models (non-parametric test, zero-inflated negative binomial, logistic regression and time-series models) were used and compared with assess trends. Over the study period, 2914 WRA cases were included in the network. A significant decrease was observed overall and for some agents such as isocyanates (p = 0.007), aldehydes (p = 0.01) and latex (p = 0.01). Conversely, a significant increase was observed for cases related to exposure to quaternary ammonium compounds (p = 0.003). The health and social sector demonstrated both a growing number of cases related to the use of quaternary ammonium compounds and a decrease of cases related to aldehyde and latex exposure. WRA declined in France over the study period. The only significant increase concerned WRA related to exposure to quaternary ammonium compounds. Zero-inflated negative binomial and logistic regression models appear to describe adequately these data.
    Occupational and environmental medicine 03/2012; 69(6):391-7. DOI:10.1136/oemed-2011-100487 · 3.23 Impact Factor
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    ABSTRACT: The main objective of the present study is to determine the prevalence of lifetime use and use in the past 30 days of narcotics in French seamen and to assess factors correlated with positive urine test in seamen as a whole. A stratified survey conducted in 19 French ports collected 1,928 self-administered questionnaires on cigarette, alcohol and narcotics consumption. Seafarers were randomly selected and interviewed during their annual seafaring aptitude consultation. Only the 1847 male respondents were included in analysis. Nearly half of the seamen had tried cannabis at some point in their life, and 16% were users in the past 30 days. Lifetime use of certain other illegal drugs (cocaine, heroin, hallucinogenic mushrooms, poppers and ecstasy) was non-negligible, but cocaine and heroin were the only ones showing exceptional prevalence of consumption over the previous 30 days. Lifetime use of drugs was non-negligible among seamen. Prevalence of recent cannabis use was elevated. Recent consumption as indicated by positive urine test correlated with age group, family situation, occupational category, geographical area, young age of first alcohol consumption and experimentation with other drugs.
    Addictive behaviors 11/2011; 37(3):335-8. DOI:10.1016/j.addbeh.2011.11.009 · 2.44 Impact Factor
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    ABSTRACT: Diseases, including cancer induced by asbestos, usually occur after many years of latency. The follow-up of employees must therefore continue after the end of their employment (retirement, redundancy, etc.) and such an arrangement has existed in France since 1996. This article reviews the literature on the post-employment monitoring arrangements that exist outside of France, particularly in other European countries, and their characteristics. This research has revealed a limited number of national experiences in Germany, Spain, Finland, Italy, Norway, Poland, and Switzerland. The medical protocols generally involve: algorithm decisions, questionnaire, physical examination, chest radiography, CT scan, and/or spirometry. Internationally, various methods exist to select employees for follow-up and to determine the frequency of subsequent examinations. Unlike Germany, which has a long experience of such medical follow-up, several of these programs are more recent. Post-occupational medical surveillance of asbestos-related disease is uncommon, monitoring arrangements vary and depend on medical and also on social factors. The French system of post-occupational monitoring can undoubtedly improve but it bears comparison with arrangements in other countries, where these are even present.
    Revue des Maladies Respiratoires 04/2011; 28(4):556-64. · 0.49 Impact Factor
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    ABSTRACT: Introduction Diseases, including cancer induced by asbestos, usually occur after many years of latency. The follow-up of employees must therefore continue after the end of their employment (retirement, redundancy, etc.) and such an arrangement has existed in France since 1996. This article reviews the literature on the post-employment monitoring arrangements that exist outside of France, particularly in other European countries, and their characteristics. State of art This research has revealed a limited number of national experiences in Germany, Spain, Finland, Italy, Norway, Poland, and Switzerland. The medical protocols generally involve: algorithm decisions, questionnaire, physical examination, chest radiography, CT scan, and/or spirometry. Perspectives Internationally, various methods exist to select employees for follow-up and to determine the frequency of subsequent examinations. Unlike Germany, which has a long experience of such medical follow-up, several of these programs are more recent. Conclusions Post-occupational medical surveillance of asbestos-related disease is uncommon, monitoring arrangements vary and depend on medical and also on social factors. The French system of post-occupational monitoring can undoubtedly improve but it bears comparison with arrangements in other countries, where these are even present.
    Revue des Maladies Respiratoires 04/2011; 28(4):556-564. DOI:10.1016/j.rmr.2010.08.012 · 0.49 Impact Factor
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    ABSTRACT: Hospital surveillance systems have been established to monitor occupational blood exposures. We compare short-term monitoring with long-term monitoring of data analysis over 11 years and 21 institutions to identify variations in the number of reported exposures. Short-term monitoring examines the current number of exposures compared to their average over previous years. Long-term monitoring detects trends over several years by various exposure characteristics (place, staff, procedure, etc) through estimating rates of change and using the best linear unbiased predictors (BLUPs) to prevent artefactual trends due to the many categories for each characteristic. Graphical representations of estimated rates help detect change and differences in rates of change. Annual monitoring allowed detection of significant changes in the number of reported exposures. Long-term monitoring identified moderate trends over time. The BLUP corrected the estimate of each specific annual rate of change and allowed all other rates to reduce the random variability around the mean change for more specificity. League tables showed significant increases or decreases compared to no change. League tables for two-by-two comparisons allowed reliable comparisons between estimates of the rates of change, although with spurious ranking. Funnel plots enabled quick detection of changes in trends within specified confidence intervals. Long-term trends agreed with the dominant type of annual changes over the 11 years but were not as sensitive. The two methods have different uses. Both are helpful for assessing short-term sudden and long-term minor changes in number of exposures, possibly reflecting the success or otherwise of introducing specific safety devices or guidelines.
    Occupational and environmental medicine 11/2010; 67(11):785-91. DOI:10.1136/oem.2010.055699 · 3.23 Impact Factor
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    ABSTRACT: The aim of this study is to assess tobacco consumption, nicotine dependence as diagnosed by Fagerström test, alcohol consumption, alcohol dependence as diagnosed by CAGE questionnaire and drug consumption in French seamen. Results are presented according to job category: fishermen and merchant seamen. French seamen were recruited from a stratified survey of 19 ports in France. Subjects completed a questionnaire during their annual medical check-up. The questionnaire covered demographic and professional items, tobacco, alcohol and drug consumption behaviour. Nicotine and alcohol dependence were, respectively, assessed by the Fagerström Test for Nicotine Dependence (FTND) and a French version of the CAGE questionnaire. A urine test was used to detect cannabis derivatives. Prevalence rates for current smoking and daily alcohol consumption were higher in fishermen than merchant seamen. The prevalence of nicotine dependence on FTND was likewise higher in fisherman smokers, who also showed more intense smoking behaviour. The category of seamen did not correlate with alcohol addiction, but differences in alcohol-related behaviour emerged between fishermen and merchant seamen. Prevalence of cannabis and other drug use was higher in merchant seamen, although the two categories of seaman did not differ with respect to recent use of cannabis. Demographic factors cannot fully explain these differences, as multivariate analysis showed significantly greater risks in marine fisheries. Alcohol and tobacco consumption are a major public health problem for seafarers. Fishermen seem to be more liable to high consumption. Working conditions may explain these differences.
    International Archives of Occupational and Environmental Health 11/2009; 83(5):497-509. DOI:10.1007/s00420-009-0473-y · 2.20 Impact Factor
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    ABSTRACT: Objective Several epidemiological studies have reported increased morbidity or mortality from cervical cancer in workers exposed to trichloroethylene (TCE). This chlorinated solvent is classified as probably carcinogenic by the International Agency for Research on Cancer (IARC, group 2), but is still employed in the screw-cutting industry in, for example, the French department Haute-Savoie. A retrospective pilot study was performed on medical and work-related data collected over a one-year period by an occupational physician who suspected the presence of a cancer cluster. The objective was an initial risk assessment to determine the usefulness of a possible dedicated epidemiological study. Materials and methods The data comprised history of TCE exposure at work and of cervical conization (indicating cervical cancer). The risk of cervical pathology linked to TCE exposure was assessed by odds ratio (OR) and Chi2 test. Socioeconomic category was taken into account. Exposure was reassessed for all patients reporting history of cervical conization to estimate measurement bias (concomitant recording of pathology and exposure). Results In the 777 women seen in occupational medicine consultation during the year in question, there were 18 cases of cervical conization, in 11 of which the occupational physician recorded TCE exposure. The risk of cervical pathology associated with TCE exposure was 4.55 (1.88–11.00) and remained elevated after adjustment for socioeconomic category OR = 3.95 (1.36–11.49). After reassessment of TCE exposure, risk remained elevated, although the raw OR was no longer statistically significant OR = 1.84 (0.71–4.75). Discussion Literature data and the present pilot study suggest an increase in cervical cancer risk in workers exposed to TCE. None of the published epidemiological studies, however, focused specifically on this association and known risk factors (such as human papilloma virus) were not taken into account. A dedicated study appears feasible and justified, has been set up and is presently underway.
    Archives des Maladies Professionnelles et de l Environnement 09/2009; 70(4):417-424. DOI:10.1016/j.admp.2009.04.011 · 0.09 Impact Factor
  • Archives des Maladies Professionnelles et de l Environnement 06/2009; 70(3):327-336. DOI:10.1016/j.admp.2008.12.013 · 0.09 Impact Factor

Publication Stats

481 Citations
104.68 Total Impact Points

Institutions

  • 2007–2014
    • Hospices Civils de Lyon
      Lyons, Rhône-Alpes, France
  • 2003–2012
    • University of Lyon
      Lyons, Rhône-Alpes, France
    • CHU de Lyon - Hôpital de la Croix-Rousse
      Lyons, Rhône-Alpes, France
  • 2001–2009
    • Claude Bernard University Lyon 1
      • Unité mixte de recherche epidémiologique et de surveillance transport travail environnement
      Villeurbanne, Rhône-Alpes, France
  • 2000–2004
    • Centre Hospitalier Lyon Sud
      Lyons, Rhône-Alpes, France