Yoko Yajima

Publications (2)0.58 Total impact

• Article: QOL after head and neck reconstruction: evaluation of Japanese patients using SF-36 and GOHAI.

  Makoto Hikosaka, Hiroko Ochiai, Masato Fujii, Noboru Habu, Yoko Yajima, Toshioki Sakurai, Seiji Bito
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  ABSTRACT: To evaluate the health-related quality of life (HRQOL) of Japanese patients with head and neck cancer after treatment. Cross-sectional, descriptive study. Twenty-nine patients who underwent resection and reconstruction of the head and neck cancer between September 2001 and January 2008 at the National Hospital Organization Tokyo Medical Center completed the Short Form 36 (generic QOL measure) and the General Oral Health Assessment Index (oral-specific QOL measure). The generic QOL of the patients was relatively maintained while oral-specific QOL was impaired compared to the Japanese norms. The patients with musculo-cutaneous flaps and 1y or longer after operation reported significantly lower QOL. This is a unique study on Japanese patients with relatively longer time after operation. Further evaluation with increased number of cases and disease-specific QOL scale is required to better understand the QOL of the patients.
  Auris, nasus, larynx 05/2011; 38(6):730-4. · 0.58 Impact Factor
• Article: [Hyponatremia with cisplatin administration in head and neck cancer patients].

  Yoko Yajima, Masato Fujii, Yutaka Tokumaru, Noboru Habu
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  ABSTRACT: Hyponatremia is one of the most common electrolyte disorders encountered in clinical practice of medical anticancer treatment. Cisplatin (CDDP) is a well-known chemotherapeutic agent that associates with hyponatremia. We retrospectively studied clinical features of hyponatremia CDDP administration. The incidence of hyponatremia at the first administration was 64. 1%. The significant risk factors of hyponatremia are body weight less than 60 kg, creatinin clearance less than 60mL/min, and sodium depletion and intake loss due to treatment-induced anorexia, nausea, vomiting and diarrhea. The mechanism of hyponatremia induced by CDDP is thought to be mainly renal salt wasting, and sometimes the syndrome of inappropriate secretion of antidiuretic hormone(SIADH).
  Gan to kagaku ryoho. Cancer & chemotherapy 12/2010; 37(13):2861-5.