Publications (3)3.34 Total impact
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Article: Synthesis and antibacterial activity of new fluoroquinolones containing a cis- or trans-cyclohexane moiety.
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ABSTRACT: New quinolone derivatives bearing a cis- or trans-cyclohexane side chain at the C-7 position have been synthesized and evaluated for their antibacterial activities against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa using the agar dilution method. The activities of compound 53 against these three bacteria were superior to those of the reference drug lomefloxacin. Compounds bearing a cis-cyclohexane side chain generally exhibited greater antibacterial activity than their corresponding trans-isomers.Bioorganic & medicinal chemistry letters 10/2012; · 2.65 Impact Factor -
Article: 3,3'-[(tert-Butoxy-carbon-yl)aza-nedi-yl]dipropanoic acid.
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ABSTRACT: The title compound, C(11)H(19)NO(6), is an important inter-mediate for the synthesis of cephalosporin derivatives. The N atom is in a planar configuration. In the crystal, mol-ecules are linked into zigzag layers parallel to (100) by O-H⋯O hydrogen bonds.Acta Crystallographica Section E Structure Reports Online 01/2009; 65(Pt 6):o1408. · 0.35 Impact Factor -
Article: trans-4-[(Phenyl-sulfon-yloxy)meth-yl]cyclo-hexa-necarboxylic acid.
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ABSTRACT: The title compound, C(14)H(18)O(5)S, is an important inter-mediate for the synthesis of poly(amido-amine) dendrimers. The cyclo-hexane ring adopts a chair conformation with its two substituents in equatorial positions. In the crystal structure, mol-ecules form centrosymmetric dimers via O-H⋯O hydrogen bonds.Acta Crystallographica Section E Structure Reports Online 01/2008; 64(Pt 9):o1703. · 0.35 Impact Factor
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Institutions
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2008–2012
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Sichuan University
- School of Pharmacy
Chengdu, Sichuan Sheng, China
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