Xiang-Chun Ding

Publications (3)0.66 Total impact

• Article: Association between Serum Platelet-Derived Growth Factor BB and Degree of Liver Damage, Fibrosis and Hepatitis B e Antigen (HBeAg) Status in CHB Patients.

  Xiang-Chun Ding, Li-Na Ma, Yu-Fang Li, Xiao-Yan Liu, Xu Zhang, Jun-Ying Liu, Yun-Jian Sheng, Da-Zhi Zhang, Huai-Dong Hu, Hong Ren
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  ABSTRACT: Background/Aims: The objective of this study was to determine the association of PDGF-BB with degree of liver damage, fibrosis and HBeAg status in CHB patients. Methodology: A total of 740 patients with previously untreated chronic hepatitis B were included in the study. We conducted the correlations analysis of serum PDGF-BB with the age, gender, medical history, serum HBV-DNA, liver function parameters and serum fibrosis markers (HA, PCIII, CIV, LN), analyzed the correlations of degree of liver damage with liver fibrosis markers and the serum levels of PDGF-BB and compared serum liver fibrosis markers and levels of PDGF-BB between HbeAg-negative and HbeAg-positive CHB patients. Results: Liver function parameters and serum liver fibrosis markers were significantly correlated with serum PDGF-BB (p<0.01). Liver fibrosis markers and serum levels of PDGF-BB in CHB were positive correlated with degree of liver damage. Serum levels of PDGF-BB in HBeAg-negative CHB was significantly higher than that in the HBeAg-positive CHB (p<0.05). Conclusions: Serum levels of PDGF-BB can reflect degree of liver damage and degree of liver fibrosis in CHB. Serum levels of PDGF-BB in HBeAg-negative CHB were higher than the HBeAg-positive CHB.
  Hepato-gastroenterology 06/2012; 59(120). · 0.66 Impact Factor
• Article: [The clinical significance of serum platelet-derived growth factor (PDGF-BB) in HBeAg positive and negative chronic hepatitis B patients].

  Xiang-chun Ding, Li-nan Ma, Yu-fang Li, Hai Wu, Ping Zhang, Xu Zhang
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  ABSTRACT: Not Abstract.
  Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 01/2011; 19(1):58-9.
• Article: [Effect of aspartame on the liver cirrhosis model induced by the complex factors].

  Xiang-Chun Ding, Li-Na Ma, Xue-Xin Chen
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  ABSTRACT: Not Abstract.
  Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 04/2009; 17(3):229-30.