Wei Yi

Publications (2)7.24 Total impact

• Article: The neural pathway of reflex regulation of electroacupuncture at orofacial acupoints on gastric functions in rats.

  Jianhua Liu, Wenbin Fu, Wei Yi, Zhenhua Xu, Nenggui Xu
  [show abstract] [hide abstract]
  ABSTRACT: Acupuncture has a reflex regulation in gastrointestinal functions, which is characterized with segment. In the present study, the neural pathway of electroacupuncture (EA) at orofacial acupoints (ST2) on gastric myoelectric activity (GMA) in rats was investigated. The results indicated that EA at ST2 facilitated spike bursts of GMA, which is similar to EA at limbs and opposite to EA at abdomen. The excitatory effect was abolished by the transaction of infraorbital nerves, dorsal vagal complex lesion, and vagotomy, respectively. In addition, microinjection of L-glutamate into the nucleus of the solitary tract (NTS) attenuated the excitatory effect. All these data suggest that the dorsal vagal complex is involved in the reflex regulation of EA at orofacial acupoints on gastric functions and NTS-dorsal motor nucleus of the vagus (DMV) inhibitory connections may be essential for it.
  Evidence-based Complementary and Alternative Medicine 01/2012; 2012:753264. · 4.77 Impact Factor
• Article: Extrasegmental analgesia of heterotopic electroacupuncture stimulation on visceral pain rats.

  Jianhua Liu, Wenbin Fu, Wei Yi, Zhenhua Xu, Yuan Liao, Xinran Li, Jiesi Chen, Xuefang Liu, Nenggui Xu
  [show abstract] [hide abstract]
  ABSTRACT: Acupuncture has been applied in the clinic to treat visceral pain for a long time. However, the underlying mechanism still remains unknown. In the present study, extrasegmental analgesia of electroacupuncture (EA) at orofacial acupoints on visceral pain rats was investigated. The results revealed that nociceptive EA stimulation applied at heterotopic acupoints or nonacupoints to activate A(δ) and/or C fibers induced c-fos expression in the paratrigeminal nucleus (PTN) and significantly inhibited acetic acid-induced abdominal contractions and c-fos expression in the nucleus of the solitary tract (NTS). However, non-nociceptive EA or non-EA stimulation applied at heterotopic acupoints was totally ineffective. After infraorbital nerves transaction or pretreated by capsaicin, the EA analgesia was dramatically inhibited. Snake venom pretreatment had no influence on this analgesia. Consequently, heterotopic EA stimulation trigger the pain-inhibiting effect of diffuse noxious inhibitory controls (DNIC), in which PTN-NTS secondary neural pathway may be involved and small-diameter (A(δ) and/or C) fibers are crucial.
  Brain research 02/2011; 1373:160-71. · 2.46 Impact Factor