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ABSTRACT: Wilms tumor is one of the most common solid malignancies of childhood. The long-term result of the surgical treatment of this tumor with adjuvant chemotherapy and radiation has been reported from many western centers. However, there is paucity of literature on the long-term outcome of treatment for this tumor from the developing world. We planned a prospective study that started in 1999 to evaluate the 5-year tumor-free survival of Wilms tumor treated on a fixed protocol from a university hospital in India.
All consecutive children with Wilms tumor who were seen by any of the 3 investigators (2 pediatric oncologists, 1 pediatric surgeon) between 1999 and 2003 at the Advanced Pediatric Centre were included in the study. Each patient was entered into a database. Their demographic profile and events during the treatment and follow-up were recorded. This was later analyzed.
Seventy-five percent 5-year tumor-free survival has been achieved within the limitations of treatment in the developing world. The morbidity during therapy was 10% and the mortality 5%. This was based on the treatment of this common childhood malignancy at Chandigarh on a modified International Society of Pediatric Oncology protocol.
Journal of Pediatric Hematology/Oncology 03/2011; 34(1):57-62. · 1.16 Impact Factor
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ABSTRACT: We report a rare case of progressive familial intrahepatic cholestasis type 2 from India. The diagnosis was confirmed on the basis of gene mutation analysis. The child had intense pruritus refractory to conventional medical management. As liver biopsy did not reveal any cirrhosis, partial external biliary diversion was considered as an alternative to liver transplant. We performed cholecystoappendicostomy rather than the conventional method of using an ileal loop as a conduit between the gall bladder and abdominal wall. Child recovered completely.
Indian pediatrics 07/2010; 47(7):626-8. · 1.05 Impact Factor
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Journal of pediatric urology 06/2009; 5(5):423-4. · 1.38 Impact Factor
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Sujit K Chowdhary
The Indian Journal of Pediatrics 10/2008; 75(9):923. · 0.52 Impact Factor
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Sujit K Chowdhary
Journal of Indian Association of Pediatric Surgeons 04/2008; 13(2):47-8.
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ABSTRACT: The authors report on a baby with imperforate anus associated with duplication of descending colon, double pouch colon type IV, duplication of the urinary bladder, and a bifid penis. The interesting presentation of this problem and its management is discussed with a brief review of the probable embryologic basis for such an anomaly. Such a duplication of pouch colon has not been described previously.
Journal of Pediatric Surgery 03/2003; 38(2):e1. · 1.45 Impact Factor
