Stefanie Mersmann

Publications (2)19.32 Total impact

• Article: Synthesis of sulfondiimines by N-chlorosuccinimide-mediated oxidative imination of sulfiliminium salts.

  Mathieu Candy, Carole Guyon, Stefanie Mersmann, Jia-Rong Chen, Carsten Bolm
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  ABSTRACT: Access to sulfondiimines: The oxidative one-pot chlorination-imination sequence of in situ generated free sulfilimines by N-chlorosuccinimide (NCS) allows the preparation of N-monosubstituted sulfondiimines under mild reaction conditions with excellent functional-group tolerance (see scheme, Mes=2,4,6-trimethylphenylsulfonyl).
  Angewandte Chemie International Edition 03/2012; 51(18):4440-3. · 13.45 Impact Factor
• Article: Enantioselective organocatalytic synthesis of quaternary α-amino acids bearing a CF3 moiety.

  Ralph Husmann, Erli Sugiono, Stefanie Mersmann, Gerhard Raabe, Magnus Rueping, Carsten Bolm
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  ABSTRACT: A highly enantioselective Friedel-Crafts reaction catalyzed by a chiral phosphoric acid was developed. N-Boc-protected ethyl trifluoropyruvate imine was activated by 6 mol % of catalyst and reacted with a wide variety of indole derivatives to afford quaternary α-amino acids in excellent yields (up to 99%) and high enantioselectivities (up to 98:2 er).
  Organic Letters 03/2011; 13(5):1044-7. · 5.86 Impact Factor