Seung-Beom Han

Korea University, Sŏul, Seoul, South Korea

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Publications (40)73 Total impact

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    ABSTRACT: The current study aimed to investigate the association between the number of remaining teeth and bone mineral density (BMD) using data from the Korean National Health and Nutrition Examination Survey (KNHANES) 2008-2010. This study enrolled 7315 Korean subjects (3364 men over 50 years of age and 3951 postmenopausal women). BMD was measured using dual-energy X-ray absorptiometry at three sites: the total femur (TF), femur neck (FN), and lumbar spine (LS). The number of teeth present was categorized into four groups (≤10, 11-20, 21-25, and ≥26 teeth). More remaining teeth were significantly associated with a higher BMD at the TF, FN, and LS in postmenopausal women after adjusting for all the covariates, but not in elderly men. In both sexes, subjects with a normal BMD tended to have more remaining teeth than those who were diagnosed with osteopenia and osteoporosis. A lower prevalence of osteoporosis was also significantly associated with more remaining teeth (number of teeth ≥26) in postmenopausal women. This trend was statistically significant in osteoporosis at the FN (p for trend=0.019). The number of remaining teeth was associated with osteoporosis, especially at the FN, in postmenopausal women. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
    Maturitas 07/2015; DOI:10.1016/j.maturitas.2015.07.016 · 2.86 Impact Factor
  • Dae-Hee Lee · Sung-Chul Park · Hyung-Joon Park · Seung-Beom Han
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    ABSTRACT: Open-wedge high tibial osteotomy (HTO) cannot always accurately correct limb alignment, resulting in under- or over-correction. This study assessed the relationship between soft tissue laxity of the knee joint and alignment correction in open-wedge HTO. This prospective study involved 85 patients (86 knees) undergoing open-wedge HTO for primary medial osteoarthritis. The mechanical axis (MA), weight-bearing line (WBL) ratio, and joint line convergence angle (JLCA) were measured on radiographs preoperatively and after 6 months, and the differences between the pre- and post-surgery values were calculated. Post-operative WBL ratios of 57-67 % were classified as acceptable correction. WBL ratios <57 and >67 % were classified as under- and over-corrections, respectively. Preoperative JLCA correlated positively with differences in MA (r = 0.358, P = 0.001) and WBL ratio (P = 0.003). Difference in JLCA showed a stronger correlation than preoperative JLCA with differences in MA (P < 0.001) and WBL ratio (P < 0.001). Difference in JLCA was the only predictor of both difference in MA (P < 0.001) and difference in WBL ratio (P < 0.001). The difference between pre- and post-operative JLCA differed significantly between the under-correction, acceptable-correction, and over-correction groups (P = 0.033). Preoperative JLCA, however, did not differ significantly between the three groups. Neither preoperative JLCA nor difference in JLCA correlated with change in posterior slope. Preoperative degree of soft tissue laxity in the knee joint was related to the degree of alignment correction, but not to alignment correction error, in open-wedge HTO. Change in soft tissue laxity around the knee from before to after open-wedge HTO correlated with both correction amount and correction error. Therefore, a too large change in JLCA from before to after open-wedge osteotomy may be due to an overly large reduction in JLCA following osteotomy, suggesting alignment over-correction during surgery. II.
    Knee Surgery Sports Traumatology Arthroscopy 07/2015; DOI:10.1007/s00167-015-3682-9 · 2.84 Impact Factor
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    ABSTRACT: This study was designed to compare the preoperative strengths and endurances of the quadriceps and hamstring muscles in patients with anterior cruciate ligament (ACL) versus posterior cruciate ligament (PCL) tears. Quadriceps and hamstring muscle strength and endurance were compared between 20 prospectively enrolled patients with isolated PCL tears and a retrospective, matched control group of 20 patients with isolated ACL tears. The maximal torque (60°/s) and total work (180°/s) of the quadriceps and hamstring were evaluated with an isokinetic testing device. Total work (1,094.4 ± 505.8 J v 797.5 ± 332.7 J, P = .035) and peak torque (129.9 ± 56.2 N ∙ m v 98.2 ± 37.4 N ∙ m, P = .046) of the quadriceps muscle on the involved side were higher in the PCL tear group than in the ACL tear group. However, there were no significant differences between the PCL tear group and ACL tear group in hamstring muscle strength (45.8 ± 42.3 N ∙ m and 46.0 ± 24.4 N ∙ m, respectively; P = .940) and endurance (429.3 ± 238.9 J and 382.4 ± 256.1 J, respectively; P = .574) on the involved side. The strength and endurance of the quadriceps muscle of the injured limb were greater after PCL tears than after ACL tears. However, there were no significant between-group differences in hamstring muscle strength and endurance on the involved side. Level III, retrospective comparative study. Copyright © 2015 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.
    Arthroscopy The Journal of Arthroscopic and Related Surgery 03/2015; 31(6). DOI:10.1016/j.arthro.2015.01.012 · 3.19 Impact Factor
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    ABSTRACT: The characteristics of anterior cruciate ligament (ACL)-derived mesenchymal stem cells (MSCs), such as proportion and multilineage potential, can be affected by donor age. However, the qualitative and quantitative features of ACL MSCs isolated from younger and older individuals have not yet been compared directly. This study assessed the phenotypic and functional differences in ACL-MSCs isolated from younger and older donors and evaluated the correlation between ACL-MSC proportion and donor age. Torn ACL remnants were harvested from 36 patients undergoing ACL reconstruction (young: 29.67 ± 10.92 years) and 33 undergoing TKA (old: 67.96 ± 5.22 years) and the proportion of their MSCs were measured. The mean proportion of MSCs was slightly higher in older ACL samples of the TKA group than of the younger ACL reconstruction group (19.69 ± 8.57% vs. 15.33 ± 7.49%, p = 0.024), but the proportions of MSCs at passages 1 and 2 were similar. MSCs from both groups possessed comparable multilineage potentiality, as they could be differentiated into adipocytes, osteocytes, and chondrocytes at similar level. No significant correlations were observed between patient age and MSC proportions at passages 0-2 or between age and MSC proportion in both the ACL reconstruction and TKA groups. Multiple linear regression analysis found no significant predictor of MSC proportion including donor age for each passage. Microarray analysis identified several genes that were differentially regulated in ACL-MSCs from old TKA patients compared to young ACL reconstruction patients. Genes of interest encode components of the extracellular matrix (ECM) and may thus play a crucial role in modulating tissue homeostasis, remodeling, and repair in response to damage or disease. In conclusion, the proportion of freshly isolated ACL-MSC was higher in elderly TKA patients than in younger patients with ACL tears, but their phenotypic and multilineage potential were comparable.
    PLoS ONE 03/2015; 10(3):e0117224. DOI:10.1371/journal.pone.0117224 · 3.23 Impact Factor
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    Jong-Hoon Park · In-Jung Chae · Seung-Beom Han · Dae-Hee Lee
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    ABSTRACT: Chondroblastoma of the proximal tibia is difficult to treat because of its epiphyseal predilection. This condition can be treated by curettage, which results in immediate restoration of stability and a reduced recurrence rate, followed by cement filling of the bone defect. Nevertheless, contact with cement can damage articular cartilage, potentially leading to severe knee osteoarthritis. Most previous reports regarding this complication described patients with giant cell tumors of the proximal tibia. We present here a patient who underwent arthroscopic treatment for cement exposure caused by articular cartilage loss of the tibial plateau, which occurred after initial curettage and cementation for chondroblastoma of the proximal tibia. To our knowledge, this is the first report on arthroscopic treatment of this condition.
    03/2015; 27(1):61-4. DOI:10.5792/ksrr.2015.27.1.61
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    ABSTRACT: We aimed to compare posterior cruciate ligament (PCL) tibial tunnel location after tibial guide insertion medial (between the PCL remnant and the medial femoral condyle) and lateral (between the PCL remnant and the anterior cruciate ligament) to the PCL stump as determined by in vivo 3-dimensional computed tomography (3D-CT). Tibial tunnel aperture location was analyzed by immediate postoperative in vivo CT in 66 patients who underwent single-bundle PCL reconstruction, 31 by over-the-PCL and 35 by under-the-PCL tibial guide insertion techniques. Tibial tunnel positions were measured in the medial to lateral and proximal to distal directions of the posterior proximal tibia. The center of the tibial tunnel aperture was located more laterally (by 2.7 mm) in the over-the-PCL group than in the under-the-PCL group (P = .040) and by a relative percentage (absolute value/tibial width) of 3.2% (P = .031). Tibial tunnel positions in the proximal to distal direction, determined by absolute value and relative percentage, were similar in the 2 groups. Tibial tunnel apertures were located more laterally after lateral-to-the-PCL tibial guide insertion than after medial-to-the-PCL tibial guide insertion. There was, however, no significant difference between these techniques in distance from the joint line to the tibial tunnel aperture. Insertion lateral to the PCL stump may result in better placement of the PCL in its anatomic footprint. Level III, retrospective comparative study. Copyright © 2015 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.
    Arthroscopy The Journal of Arthroscopic and Related Surgery 02/2015; 31(5). DOI:10.1016/j.arthro.2014.12.004 · 3.19 Impact Factor
  • Young-Soo Shin · Tae-Wan Jung · Seung-Beom Han
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    ABSTRACT: A 53-year-old woman developed a vaginal mass following an uncemented total hip arthroplasty. The mass was in direct communication with the hip through an acetabular medial wall defect after loosening of the acetabular component. The mass formation was caused simultaneously by changes secondary to polyethylene wear, a tiny delamination of the porous titanium mesh coating and a broken antirotational tab on the acetabular cup, all of which may have served as sources of metal particles. A careful evaluation of the patient's history, symptoms, X-ray findings and computed tomography scans should always be performed to ensure accurate diagnosis.
    Indian Journal of Orthopaedics 11/2014; 48(6):628-30. DOI:10.4103/0019-5413.144242 · 0.62 Impact Factor
  • Young-Soo Shin · Seung-Beom Han · Tae-Wan Jung
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    ABSTRACT: We prospectively analyzed 83 patients who underwent ceramic-on-ceramic THA using preassembled (n=22) or modular acetabular components (n=61) between June 2010 and June 2012. There were no significant differences in mean postoperative radiographic outcomes, functional outcomes, or complications between the two groups. Both groups showed satisfactory performance at the 2year follow up. Only the gender of the patients was significantly different between the two groups. Half of the women had smaller acetabular diameters accommodating a cup size of only 48-50-mm. Although a preassembled cup with a 36-mm ceramic liner is proven to be safe in the short term, future research should focus on evaluating the long-term risks.
    The Journal of Arthroplasty 06/2014; 29(12). DOI:10.1016/j.arth.2014.06.020 · 2.37 Impact Factor
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    ABSTRACT: An early diagnosis of popliteal artery pseudoaneurysm-a sequela of popliteal artery trauma-is difficult owing to its late presentation following total knee arthroplasty. The incidence of a popliteal artery pseudoaneurysm with a hematoma presenting only a peripheral nerve injury after total knee arthroplasty is also uncommon in the absence of common diagnostic features such as a pulsatile swelling with an audible bruit on auscultation. In the present report, we describe popliteal artery pseudoaneurysm following total knee arthroplasty.
    06/2014; 26(2):117-20. DOI:10.5792/ksrr.2014.26.2.117
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    ABSTRACT: The graft-healing potential of mesenchymal stromal cells (MSCs) derived from the remnants of ruptured anterior cruciate ligaments (ACLs) after ACL reconstruction may depend on the chronicity of the injury. The aim of this study was to assess the quantitative and phenotypic differences between MSCs isolated from ACL remnants in patients with (sub)acute and chronic tearing. Torn ACL remnants were harvested during ACL reconstruction from 41 patients, 24 with (sub)acute ACL (<6 months from injury to surgery) and 17 with chronic ACL (time interval >6 months) tears. MSCs isolated from these samples were assessed for quantitative and phenotypic differences, and the correlation between the proportion of MSCs and the chronicity of ACL tear was evaluated. At passage 0, the mean proportion of MSCs (CD34(-), CD44(+), CD90(+) and CD105(+)) was higher in (sub)acute than in chronic ACL tear samples (20.69% ± 7.82% versus 9.85% ± 8.01%, P < 0.001). At passages 1 and 2, however, MSC proportions did not differ significantly in the two groups. Time interval showed a negative correlation with MSC proportion only at passage 0 (r = -0.505, P < 0.001). The optimal cutoff value for time from injury to surgery yielding <10% freshly isolated ACL-MSCs, a percentage expected to have low tissue healing potential, was 23.5 months. The proportion of freshly isolated MSCs was higher in samples from patients with (sub)acute tearing than in chronic ACL tearing and negatively correlated with the time interval between trauma and surgery.
    Cytotherapy 01/2014; 16(5). DOI:10.1016/j.jcyt.2013.08.001 · 3.10 Impact Factor
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    ABSTRACT: Multiple total knee arthroplasty (TKA) failure resulting from a recurrent infection is a challenging problem. Knee arthrodesis is one treatment option that normally involves the application of an external fixator, plate fixation, and intramedullary nailing. However, these approaches are not always successful, and a reinfection is a risk, particularly in older, medically compromised patients. This paper reports a new arthrodesis technique that uses a bundle of flexible intramedullary rods and an antibiotic-loaded cement spacer. This technique was used in two cases of multiple TKA failure that resulted from a recurrent infection. The procedure was successful in both cases with no evidence of rod or cement failure. Two advantages of this procedure are infection eradication and mechanical strength. However, this procedure should only be used for medically compromised elderly patients at high risk of rerevision TKA failure resulting from persistent periprosthetic infection because rod fracture or loosening can occur with time.
    The Journal of the Korean Orthopaedic Association 01/2014; 49(1):79. DOI:10.4055/jkoa.2014.49.1.79
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    ABSTRACT: This is the first case report on the effects of teriparatide on the course of healing of an intertrochanteric hip fracture with unusually excessive callus formation even after discontinuation of treatment in an elderly woman. This case highlights the long-term effects of parathyroid hormone, even after administration of short-term, intermittent dosages for healing of osteoporotic fracture.
    01/2014; 26(1):41. DOI:10.5371/hp.2014.26.1.41
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    ABSTRACT: The purpose of this study was to compare the clinical outcome of femoral shaft fracture treatment with intramedullary nailing performed using a greater trochanter and a piriformis entry nail.
    01/2014; 27(4):287. DOI:10.12671/jkfs.2014.27.4.287
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    ABSTRACT: High tibial osteotomy (HTO) is a popular surgical procedure for osteoarthritis of the knee with varus deformity. In general, HTO has shown sufficient clinical outcomes with careful patient selection and correct surgical technique. Among various surgical techniques, medial opening-wedge and lateral closing-wedge HTO are widely used. This report includes basic principles and current trends in patient selection and preoperative evaluations and planning, operative technique, complications, and rehabilitation protocol in medial opening-wedge HTO.
    The Journal of the Korean Orthopaedic Association 01/2014; 49(2):85. DOI:10.4055/jkoa.2014.49.2.85
  • Dae-Hee Lee · Young-Soo Shin · Jin-Ho Jeon · Dong-Won Suh · Seung-Beom Han
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    ABSTRACT: The aim of this study was to investigate the mechanism underlying the development of gap differences in total knee arthroplasty using the navigation-assisted gap technique and to assess whether these gap differences have statistical significance. Ninety-two patients (105 knees) implanted with cruciate-retaining prostheses using the navigation-assisted gap balancing technique were prospectively analysed. Medial extension and flexion gaps and lateral extension and flexion gaps were measured at full extension and at 90° of flexion. Repeated measures analysis of variance was used to compare the mean values of these four gaps. The correlation coefficient between each pair of gaps was assessed using Pearson's correlation analysis. Mean intra-operative medial and lateral extension gaps were 20.6 ± 2.1 and 21.7 ± 2.2 mm, respectively, and mean intra-operative medial and lateral flexion gaps were 21.6 ± 2.7 and 22.1 ± 2.5 mm, respectively. The pairs of gaps differed significantly (P < 0.05 each), except for the difference between the medial flexion and lateral extension gaps (n.s.). All four gaps were significantly correlated with each other, with the highest correlation between the medial and lateral flexion gaps (r = 0.890, P < 0.001) and the lowest between the medial flexion and lateral extension gaps (r = 0.701, P < 0.001). Medial and lateral flexion and extension gaps created using the navigation-assisted gap technique differed significantly, although the differences between them were <2 mm, and the gaps were closely correlated. These narrow ranges of statistically acceptable gap differences and the strong correlations between gaps should be considered by surgeons, as should the risks of soft tissue over-release or unintentional increases in extension or flexion gap after preparation of the other gap. LEVEL OF EVIDENCE: III.
    Knee Surgery Sports Traumatology Arthroscopy 09/2013; 22(8). DOI:10.1007/s00167-013-2689-3 · 2.84 Impact Factor
  • Dae-Hee Lee · Dong-Ki Lee · Young-Soo Shin · Seung-Beom Han
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    ABSTRACT: We analyzed 119 knees implanted with mobile bearing floating platform prostheses using the navigation-assisted gap balancing technique to analyze the relationship between intraoperative sagittal movement of floating platforms and soft tissue balancing. The 95 (79.8%) knees were classified into the positive rollback group (mean insert posterior rollback 5.86±1.24mm), and the remaining 24 (20.2%) into the negative rollback group. Lateral flexion gap (LFG) differed significantly between knees with positive and negative rollback (20.5±1.7mm vs 22.1±1.7mm, P=.021). Only LFG significantly influenced the occurrence of bearing sagittal movement. Sagittal translation of the insert occurred in about 80% of knees implanted with mobile bearing floating platforms in TKA, and was affected by flexion gaps, especially on the lateral side.
    The Journal of arthroplasty 05/2013; 28(10). DOI:10.1016/j.arth.2013.04.019 · 2.37 Impact Factor
  • Dae-Hee Lee · Dong-Ki Lee · Young-Soo Shin · Seung-Beom Han
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    ABSTRACT: We evaluated 106 knees that underwent primary total knee arthroplasty (TKA) with the navigation-assisted gap balancing technique using an e.-motion cruciate retaining floating platform (FP) mobile-bearing prosthesis to prospectively assess the survival of the e.-motion FP system after a minimum follow-up of 4years. There was no evidence of any complications, including dissociation or breakage of the polyethylene liner or component loosening at last follow up (5.1±0.6years). Four knees, however, required re-operation, three for distal femoral fracture, and one for infection. The estimated 5-year prosthesis survival rates without revision for any reason and for prosthesis-associated problems were 96.2% and 100%, respectively. The e.-motion floating platform, with a cruciate retaining design under navigation guidance, demonstrated excellent clinical results and 5-year survival rate.
    The Journal of arthroplasty 04/2013; 28(10). DOI:10.1016/j.arth.2013.03.002 · 2.37 Impact Factor
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    ABSTRACT: OBJECTIVE: The purpose of this study was to describe the radiological healing process after open reduction and internal fixation (ORIF) of humeral shaft fractures with plate. MATERIALS AND METHODS: We reviewed the data of 53 consecutive patients who had undergone rigid plate fixation of OTA 12 A or B humeral shaft fracture. The mean age of the patients at the time of surgery was 39.4 (range 16-82). Quality of reduction and healing process was analysed on radiographs. Clinical symptom and disabilities of the arm, shoulder and hand (DASH) scores were recorded at follow-up visits. RESULTS: There were 28 compression and 25 neutralization platings. The mean gap size on the postoperative radiograph was 1.4 (range 0.1-6.1). 50 cases (94.3 %) healed, while three cases ended up with non-union. 28 (52.8 %) cases showed primary healing and 22 cases (41.5 %) showed secondary healing with callus bridging. Among the cases with secondary healing, callus formation with resorption was identified in 13 cases. The type of fracture, mode of compression and size of gap on radiographs after rigid plate fixation were found to be statistically significant factors for healing type (p = 0.026, 0.002, and <0.001, respectively). Three cases with non-union showed no improvement in DASH scores. CONCLUSION: Both primary and secondary healing processes were observed after rigid plate fixation of OTA 12 A or B humeral shaft fractures. Our study revealed that size of gap, mode of compression, type of fracture could affect the type of healing, and that periosteal callus formation can occur after rigid plate fixation.
    Archives of Orthopaedic and Trauma Surgery 03/2013; DOI:10.1007/s00402-013-1727-4 · 1.36 Impact Factor
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    Seung-Beom Han · Young-Soo Shin
    01/2013; 26(2):156. DOI:10.12671/jkfs.2013.26.2.156
  • Dae-Hee Lee · Kyung-Wook Nha · Sung-Joon Park · Seung-Beom Han
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    ABSTRACT: PURPOSE: To determine whether navigation-assisted intraoperative lower limb alignment in open wedge high tibial osteotomy (HTO) correlates with preoperative and postoperative radiographic alignment. METHODS: This prospective study involved 35 patients (39 knees) who underwent navigation HTO for primary medial osteoarthritis. The mechanical axis (MA) and weight-bearing line (WBL) ratio were calculated from preoperative radiographs, intraoperative navigation, and postoperative (6 months) radiographs. Reliability between navigation and radiographic alignment was analyzed by use of intraclass correlation coefficients (ICCs) with thresholds as follows: good, greater than 0.75; fair, 0.4 to 0.75; and poor, less than 0.4. The surgical target for the MA was a final valgus overcorrection of 2° to 8°, and the WBL ratio target was between 50% and 70%. Outliers for differences between intraoperative navigation and postoperative radiographic results were defined as greater than ±3° for the MA and greater than ±10% for the WBL ratio. RESULTS: The MA target was achieved in 33 of 39 knees (84.6%), and the WBL ratio target was achieved in 30 of 39 knees (74.4%). ICCs for navigational reliability were good for preoperative MA and WBL ratio and fair for postoperative MA and WBL ratio. The ICCs for the MA were better than those for the WBL ratio for both preoperative and postoperative measurements. The differences between the number of outliers between the navigation and radiographic MA and WBL were greater postoperatively than preoperatively. In addition, the postoperative differences in the extent of the outliers between navigation and radiographic measurements were greater for WBL ratios than the MA (P = .023). CONCLUSIONS: This study found that use of a navigation system achieved the target value for MA lower limb correction in over 80% of open wedge HTO cases, using radiographic data as the gold standard for alignment. Because the navigational measurements of lower limbs during open wedge HTO did not correlate with postoperative radiographic alignment, corrections should not be based solely on navigational results. In assessing the reliability of navigational open wedge HTO for correction of lower limb alignment, the MA is a better radiologic parameter than the WBL ratio. LEVEL OF EVIDENCE: Level IV, therapeutic case series.
    Arthroscopy The Journal of Arthroscopic and Related Surgery 08/2012; 28(12). DOI:10.1016/j.arthro.2012.05.881 · 3.19 Impact Factor