Publications (2)2.39 Total impact
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ABSTRACT: Magnesium deficiency has been implicated as a factor in numerous chronic diseases and previous studies suggest a greater prevalence of occult magnesium deficiency among older adults. Serum is the choice for the assessment of most analyses used in clinical medicine, although serum magnesium concentrations have been shown to be poor predictors of intracellular magnesium concentration. The aim of this study was to compare intracellular and extracellular magnesium concentrations in geriatric outpatients. Moreover, we examined whether a significant correlation between magnesium parameters and clinical outcome existed. Cross-sectional study. Geriatric medicine outpatient clinic of a university hospital. A total of 246 patients with a mean age of 71.9 ± 5.7 years were involved. Intra-erythrocyte magnesium levels were analyzed with atomic absorption spectrophotometry. Serum magnesium levels were within normal range in all patients, whereas intra-erythrocyte magnesium measurements were low in 57% of the patients. Increase in serum levels were together with just only a slightly increase in intra-erythrocyte measurements and the relationship was very weak. Intra-erythrocyte Mg levels were not significantly correlated with many laboratory or clinical parameters. Our results confirm that intra-erythrocyte Mg does not correlate with serum levels and clinical parameters in geriatric outpatients, but further studies are needed to define the correlation.The Journal of Nutrition Health and Aging 10/2010; 14(10):810-4. · 2.39 Impact Factor
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ABSTRACT: Objectives. Resveratrol is a natural polyphenol present in red wine and various foods. The aim of this study was to investigate its effects on body weight, several biochemical parameters, blood pressure, and heart rate in rats. Material and Methods. In this preliminary study, rats were divided into two equal groups according to body weight (n = 20 each) to investigate the effects of resveratrol on two different weight groups, one relatively higher than the other. The first group constituted 10− to 12−week−old male Sprague−Dawley rats with a mean body weight of 235 g and the second rats weighing approximately 284 g. Both groups were divided into control (n = 10) and experimental (n = 10) groups. In the two experimental groups, resveratrol was administered (20 mg/kg) in drink− ing water for 24 weeks. After one week of training, systolic arterial blood pressure and heart rate were recorded in all the groups. Changes due to resveratrol administration in body weight and blood glucose, total cholesterol, aspar− tate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma−glutamyl transpeptidase (GGT), and uric acid (UA) levels were compared with the controls. Results. There were statistically significant decreases in weight gain, total cholesterol, and blood pressure in both experimental groups. In the lighter group, ALT level (p = 0.003) and in the heavier ALP (p = 0.049) and UA lev− els (p = 0.030) were decreased slightly compared with the controls. Conclusions. The results suggest that resveratrol ameliorated total cholesterol levels and decreased body weights with subsequent changes in systolic blood pressure while not leading to any deterioration in biochemical parame− ters (Adv Clin Exp Med 2009, 18, 4, 323-328).
Ankara, Ankara, Turkey
- Department of Internal Medicine