N Soraa

Cadi Ayyad University, Maraksh, Marrakech-Tensift-Al Haouz, Morocco

Are you N Soraa?

Claim your profile

Publications (7)1.9 Total impact

  • [Show abstract] [Hide abstract]
    ABSTRACT: In neonatal intensive care units, the incidence of nosocomial infection is high. This study aimed to determine the epidemiology of a nosocomial bacterial infection in the neonatal intensive care unit of Mohamed VI university hospital. A total of 702 newborns were included in this study. Of the 702 neonates studied, 91 had developed a nosocomial infection. The incidence rate was 13% and incidence density was 21.2 per 1000 patient-days. The types of infection were: bloodstream infections (89%), pneumonia (6.6%), meningitis (3.3%), and urinary tract infections (1.1%). Nosocomial infection was particularly frequent in cases of low birth weight, prematurity, young age at admission, umbilical venous catheter, and mechanical ventilation. Multiresistant bacteria included enterobacteria producing betalactamase (76.9%), especially enterobacteria that were dominated by Klebsiella pneumoniae (39.7%). The mortality rate was 52.7% in nosocomial infections, 19 (20.87%) of whom had septic shock. The results of this study show that nosocomial infection is an intrahospital health problem that could be remedied by a prevention strategy.
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie. 06/2014;
  • [Show abstract] [Hide abstract]
    ABSTRACT: IntroductionThe available microbiological data on community-acquired peritonitis in children are inadequate, and antibiotic therapy is not consensual. Our work aims to study the bacteriology of peritonitis in children in our region and discuss the appropriate antibiotherapy.Patients and methodsA descriptive study spread over one year. We collected cases of peritonitis in which a microbiological study of peritoneal fluid was performed.ResultsOf 38 cases, the most frequently isolated bacteria is Escherichia coli (E. coli) (50%). Its sensitivity was 64% to amoxicillin–clavulanate, 93.33% to third generation cephalosporins (C3G) and 100% to ertapenem and aminozides.Conclusion We find a high rate of resistance of E. coli to amoxicillin–clavulanic acid. This prompts us to reconsider our therapeutic approach. We believe that the association C3G + aminoglycoside + metronidazole should be used first-line in the pediatric peritonitis in our context.
    Annales francaises d'anesthesie et de reanimation 01/2013; 32(1):60–62. · 0.77 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: INTRODUCTION: The available microbiological data on community-acquired peritonitis in children are inadequate, and antibiotic therapy is not consensual. Our work aims to study the bacteriology of peritonitis in children in our region and discuss the appropriate antibiotherapy. PATIENTS AND METHODS: A descriptive study spread over one year. We collected cases of peritonitis in which a microbiological study of peritoneal fluid was performed. RESULTS: Of 38 cases, the most frequently isolated bacteria is Escherichia coli (E. coli) (50%). Its sensitivity was 64% to amoxicillin-clavulanate, 93.33% to third generation cephalosporins (C3G) and 100% to ertapenem and aminozides. CONCLUSION: We find a high rate of resistance of E. coli to amoxicillin-clavulanic acid. This prompts us to reconsider our therapeutic approach. We believe that the association C3G+aminoglycoside+metronidazole should be used first-line in the pediatric peritonitis in our context.
    Annales francaises d'anesthesie et de reanimation 11/2012; · 0.77 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: The healthy carrier of Streptococcus pneumoniae (S. pneumoniae) has been studied very little at the national level. With the emergence of antibiotic-resistant strains worldwide, and the emergence of new serotypes, an epidemiological survey is needed before the vaccine can be introduced in Morocco. This study's objective was to determine the prevalence and risk factors of pneumococcal nasopharyngeal carriage in children less than 2 years of age in the Marrakech region and to assess the antibiotic susceptibility of the isolates and the serotypes present prior to the introduction of the conjugate pneumococcal vaccine. From 2008 to 2009, 660 nasopharyngeal samples were collected on children under 2 years of age during scheduled visits to dispensaries for routine immunization in the Marrakech region. S. pneumoniae carriage was found in 45.8% of children. Of the 660 samples, 302 strains were isolated. The percentage of pneumococcal strains with reduced susceptibility to penicillin (PRSP) was 34.7%. Among these strains, 87.1% showed low-level resistance and 12.9% high-level resistance. Resistance to amoxicillin was found in 3.3% of the strains and no strains were resistant to cefotaxime. Several risk factors for pneumococcal carriage were identified, the main ones being breastfeeding less than 2 months, the presence of more than one sibling, passive smoking, and low socioeconomic level. The most frequent serotypes were 19F, 6, 14, 23, 18, and 9. The study of the vaccine serotype distribution showed that the theoretical vaccine coverage of the 7 valent vaccines was at 57% for all the isolates. These data show the frequency and the risk factors on nasopharyngeal carriage, and report the status of penicillin resistance of strains carrying children less than 2 years of age in the Marrakech region. The fluctuation of circulating serotypes at the national level underscores the importance of epidemiological surveillance carried out before the introduction of the heptavalent vaccine in Morocco.
    Archives de Pédiatrie 12/2011; 18(12):1265-70. · 0.36 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: The healthy carrier of Streptococcus pneumoniae (S. pneumoniae) has been studied very little at the national level. With the emergence of antibiotic-resistant strains worldwide, and the emergence of new serotypes, an epidemiological survey is needed before the vaccine can be introduced in Morocco. Objectives This study's objective was to determine the prevalence and risk factors of pneumococcal nasopharyngeal carriage in children less than 2 years of age in the Marrakech region and to assess the antibiotic susceptibility of the isolates and the serotypes present prior to the introduction of the conjugate pneumococcal vaccine. Patients and methods From 2008 to 2009, 660 nasopharyngeal samples were collected on children under 2 years of age during scheduled visits to dispensaries for routine immunization in the Marrakech region. Results S. pneumoniae carriage was found in 45.8% of children. Of the 660 samples, 302 strains were isolated. The percentage of pneumococcal strains with reduced susceptibility to penicillin (PRSP) was 34.7%. Among these strains, 87.1% showed low-level resistance and 12.9% high-level resistance. Resistance to amoxicillin was found in 3.3% of the strains and no strains were resistant to cefotaxime. Several risk factors for pneumococcal carriage were identified, the main ones being breastfeeding less than 2 months, the presence of more than one sibling, passive smoking, and low socioeconomic level. The most frequent serotypes were 19F, 6, 14, 23, 18, and 9. The study of the vaccine serotype distribution showed that the theoretical vaccine coverage of the 7 valent vaccines was at 57% for all the isolates. Conclusion These data show the frequency and the risk factors on nasopharyngeal carriage, and report the status of penicillin resistance of strains carrying children less than 2 years of age in the Marrakech region. The fluctuation of circulating serotypes at the national level underscores the importance of epidemiological surveillance carried out before the introduction of the heptavalent vaccine in Morocco.
    Archives De Pediatrie - ARCHIVES PEDIATRIE. 12/2011;
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: To evaluate the clinical and the immune status of newly HIV diagnosed patients, in Marrakech city and its neighboring area, in Morocco. We performed a retrospective study on 235 patients who have been previously confirmed for HIV infection, and underwent a CD4 T cells using flow cytometry (FacsCount, Becton Dickinson®). The mean age of patients was 34,3 ± 8,4 years (range: 14-55), with a male predominance (sex-ratio M/F=1.4). On basis of clinical data of the patients, 62% (n=146) of them were categorized as "category C", 18.4% (n=43) as "category B", and 19.6% (n=46) as "category A" according to CDC (Center for Disease Control) HIV classification. Among all of them, 60.4% (n=142) had less than 200 CD4T cells, 26% (n=61) had between 200 and 499 CD4T cells, and only 13.6% (n=32) showed a number of CD4T cells less or equal to 500/mm(3). The results of this study reflect a significant delay in the diagnosis of HIV infected patients. Therefore, this delay may compromise timely management of HIV infected individuals and enhances propagation of the epidemic in our country. These data confirm the need for intensifying prevention efforts among high-risk population. Moreover, continuing education in HIV/AIDS among healthcare providers should be reinforced.
    African health sciences 12/2010; 10(4):325-31.
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Aimto analyse western-blot HIV profiles and assess their association with clinical stages in a Moroccan HIV-1 infected population.Material and methodsWe performed a retrospective study about 124 of patients for whom the HIV infection diagnosis has been confirmed by a western-blot technique (HIV BLOT 2.2, MP Diagnostics). We used WHO (World Health Organisation) criterion to interpret the WB profiles.ResultsWe observed an overall band pattern including GP160, GP120, P66, P55, P51, GP41, P39, P31, P24 and P17 proteins in 80% of cases (99/124). Among all WB patterns, P17 band was lacking in 12% (15/124) of cases versus 6,4% (8/124) for P66, P55 and P39 respectively, and 4,8% (6/124) for P51 and 3,2% (4/124) for P31 bands.Related to the clinical stages of patients according to CDC 93 (Center for disease control) classification, we noticed that 79% (19/24) of category A, 82% (18/22) of category B and 79,5% (62/78) of category C had an overall band pattern. Compared to other clinical categories, we reported various incomplete patterns among the patients of group C: P17 was lacking in 11 of 16 cases, followed by P66 (8 cases), P55, P51 and P39 (5 cases), P31 (2 cases) and P24 (1 case), whereas, few bands were lacking among both A and B categories profiles. P17 was the only missing band in 4 of 5 incomplete patterns among category A. P39 and P55 bands were the most lacking (3/4 cases) in category B. We also described only one indeterminate profile in category A.Conclusion The Interpretation of WB band patterns in considering clinical stages may be used as an occasional tool to predicting the status of HIV infection. Nevertheless, a good and objective association requires the combination of the immune status of patients.
    Revue Francophone des Laboratoires 01/2009; 2009(416):19-22.