[Show abstract][Hide abstract] ABSTRACT: In a prospective study design, we sought to assess the effect of dipyridamole on coronary flow parameters in patients with isolated coronary artery ectasia (CAE) as compared to subjects with normal coronaries.
We enrolled 30 patients with ectasia of the left anterior descending (LAD) artery (study group), and 10 subjects with normal coronaries (control group). All subjects underwent transesophageal echocardiography to record flow velocities in the proximal LAD coronary artery, and velocity time integrals were calculated. The diameter of the proximal LAD coronary artery was measured and flow was calculated. Dipyridamole (0.56 mg/kg) was administered intravenously and measurements were repeated 5 minutes later.
At baseline, systolic and diastolic velocities, systolic, diastolic, and total velocity time integrals were significantly higher in the control group (P < 0.05 for all), yet, systolic, diastolic, and total coronary flow were significantly higher in the study group (P < 0.05 for all). Following dipyridamole administration, systolic, diastolic, and total coronary flow were still significantly higher in the study group (P < 0.05 for all), yet, there was no significant difference between the two groups regarding the other parameters, and regarding coronary reserve values (P > 0.05 for all).
We concluded that patients with isolated CAE have a higher resting coronary flow as compared to control subjects with normal coronaries. Intravenous dipyridamole administration in these patients maintained a significantly higher coronary flow, with a coronary flow reserve similar to controls.
[Show abstract][Hide abstract] ABSTRACT: Throwing competition is considered one of the field events in athletics, where the competitors aim is to achieve the greatest horizontal distance. Each stage of the movement stages has great importance in achieving the motor outcome, the athletics international regulations verifies that the throwing circle diameter is 2.50 meters, where the player performs a turn and a half. When developing the record level the world is directed to develop the physical fitness level or reaches the technical performance mechanism, therefore the progress in the record level is slow due to the close level of fitness among the players in all countries. The researcher endeavored to simulate the evolution of the record level through introducing Novelty technical performance to the throwing discus competition where the record level could be developed in a manner which depends less on the progress of the physical fitness level and mechanically increase the level of skill performance to increase the record level and in the same time does not conflict with the competition's regulations, represented in linking between the hammer turn and the discus turn as a Novelty technical performance. The descriptive method was used on a sample of one compound player.