[show abstract] [hide abstract]
ABSTRACT: In this study, results obtained by following up the changes in hematological parameter values in Wistar rats irradiated with 4 Gy and treated with calves thymic extract Thymex-L are presented. Following irradiation, white blood picture parameters were dramatically decreased and gradually increased from day 14. This elevation was higher in the Thymex-L treated group and the differences were statistically significant for total leukocyte, lymphocyte and neutrophyl granulocyte count starting from day 14. A significant increase of the monocyte count was observed only at day 28. Parameters of the red blood picture (erythrocyte count, hemoglobin concentration and packed red blood cell volume) were increased starting from day 21. We were able to conclude that treatment of irradiated Wistar rats with thymic extract results in a significant improvement of hematological parameter values.
Acta Veterinaria. 01/2006;